Gene Information

Name : irp2E (CD31A_2085)
Accession : YP_005158779.1
Strain : Corynebacterium diphtheriae 31A
Genome accession: NC_016799
Putative virulence/resistance : Virulence
Product : siderophore biosynthetic protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2153162 - 2154793 bp
Length : 1632 bp
Strand : +
Note : Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

DNA sequence :
ATGAGAGGGCGCGATATCGACCGCAACAGTGTGTTGAAGCATTACGAAGGCACCGGCCACCTGGCCCGAAAAAGCCTGTG
CCAGGAACTGTTCGAATCATCCGAGATTTATTCGGACCATGTAGCTGTCATCGCTGACGACGCACACCTGACCTACGCAC
AACTCGAGCAATCACTTTGTGTGTTCACCGAGGAGCTACGAGAAAGCGGCCTCTCGCCAGGAGACCACGTGCTACTGCAA
CTGCCAAACACCGCAGCGTATGTGGTGACTCTGCTTGCGCTGATGCGCGTGGGTGCTATCCCAACCCTGCTGCTTCCCGC
GCATAGAGAGGCCGAAGTTGCAGCGTTGTGTGAGTCTTTACACCCAGTTGCTTATATCGGTGGCCGCGACCATCTCGGTT
TTGACACCGTAGCCATGGTAGAGGCTATGGGACCCGGCGAGCTCGGACTCAAAGAACTGTGGGCCGATAACGGACCCACG
CACGACAAGGAGTCCTCGTACCGAGTTCTGCCAGGTCTCTTCACTGCCCCGATTTCTACCAAATGTTCTCCGCCTACTAA
GTGGCCGGATCCACGCAGCGTTGCGCTGAATCTTTTGTCTGGCGGAACCACGAACATGCCAAAAATAATTCCCCGGGTAC
ATGAGGCGTATGCATATAACACCCGTGCGGCGGCACAGTGCTGCGGCGTCGGGCCAGATACGGTATACTTGGCGGTTCTA
TCTACCTCTCATGATTTCGCCTTAGCTCAGCCCGGGATTCTGGGCACCTTGCTTTCGGGCGGCACTGTGGTTCTGTGCAC
CAGCGCAGCCTTCGATGAGGCGTTTCCGGCCATTGCGACCCACGGGGTCACGCTGACTGCACTAGTTCCTGCGGTAGCCC
AGGTGTGGGTGGAGGCCGCAGAGTGGTTTCCCGCAGATTTCTCTTCCTTGGAGCGAATTATCATTGGCGCAGCGGCGCTT
AACGACGGCTTAGGTGAGGCAATACAGGATCGTTTCGGTGTGCGTATCCACCAGGGTTATGGCATGGGTGAAGGCATCAC
TACGTTCACGCGTATTGATGACCCTCCAGCGGTGATTCTTGGCACGCAAGGTCGTCCCATCTCCGATGCTGACGAGTTGG
TAATCGATGGCCCGGGAGGCGAGCCGGGAGAGATACTAGAAAAGGGCCCTTATACTTTCTTCGGCTACGAAGGAAACCGC
GATACCCCGGACTGTTTCACCGAGGATGGTTTCTTCCGCACCGGTGACCGTGGCTACCTTACCGAGGACGGCAACCTGGT
GCTGTGCGGGCGCGTGGTTGAACAGATCAATCGCCTGGGCGAAAACGTCTCCCCTTCTGAGGTCGAGACACTCTTGTCTG
GAACTCCAGGCATTAGTGCTGCAGCCGTCTTCCCAATGCCAGATAGAGCACTGGGAGAGCGCACCGTTGCAGCCATCGTC
GCCCAACCAGGCGTTAACCGCTCCGCCATTCTGGATGATTTCCTCACCCGAGGCGTAGCCCGATACAAGGTGCCGGACCA
GGTGATCACTGTCGACGAAATTCCACTGATCAACATCGGCAAGGTCGACAAGAAAAAGCTGCGTGCTCTCGCGGCAGCGC
AATTTACTGACCGTGAATCCGAACAAAGCTGA

Protein sequence :
MRGRDIDRNSVLKHYEGTGHLARKSLCQELFESSEIYSDHVAVIADDAHLTYAQLEQSLCVFTEELRESGLSPGDHVLLQ
LPNTAAYVVTLLALMRVGAIPTLLLPAHREAEVAALCESLHPVAYIGGRDHLGFDTVAMVEAMGPGELGLKELWADNGPT
HDKESSYRVLPGLFTAPISTKCSPPTKWPDPRSVALNLLSGGTTNMPKIIPRVHEAYAYNTRAAAQCCGVGPDTVYLAVL
STSHDFALAQPGILGTLLSGGTVVLCTSAAFDEAFPAIATHGVTLTALVPAVAQVWVEAAEWFPADFSSLERIIIGAAAL
NDGLGEAIQDRFGVRIHQGYGMGEGITTFTRIDDPPAVILGTQGRPISDADELVIDGPGGEPGEILEKGPYTFFGYEGNR
DTPDCFTEDGFFRTGDRGYLTEDGNLVLCGRVVEQINRLGENVSPSEVETLLSGTPGISAAAVFPMPDRALGERTVAAIV
AQPGVNRSAILDDFLTRGVARYKVPDQVITVDEIPLINIGKVDKKKLRALAAAQFTDRESEQS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp2E YP_005163485.1 siderophore biosynthetic protein Virulence Not named Protein 0.0 100
irp2E YP_005134497.1 siderophore biosynthetic protein Virulence Not named Protein 0.0 99
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 3e-68 43
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 4e-68 43
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-67 42
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-67 42
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-67 42
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 2e-67 42
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-67 42
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-67 42
ybtE CAA21394.1 - Virulence HPI Protein 2e-67 42