Gene Information

Name : irp1D (CDPW8_2097)
Accession : YP_005143645.1
Strain : Corynebacterium diphtheriae PW8
Genome accession: NC_016789
Putative virulence/resistance : Virulence
Product : Fe3+-siderophore ABC transporter ATP-binding protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2219228 - 2220073 bp
Length : 846 bp
Strand : -
Note : ABC-type sugar transport systems, ATPase components

DNA sequence : 
GTGTTGCTGTCACTACTACCTGGAACCAAGGAGTTACTCACTTTGTCCGCTCAACTTACTTCCCGTTCTCTTTCTTCTGG
GTATGGGGCAGATCCCATTGTGAAAGATGTAACCCTGTCGTTTGAGTCCGGCAAGATTACGTCGATTGTCGGGCCGAATG
GTTGCGGCAAGTCAACGTTTCTGCGGACACTAGCGAGGTTGATTCGGCCTACAGCCGGTTCCGTTGAGCTGGATGGCAAG
CCACTGGGAGCCTATTCTTCGCGCGAGTTGGCAAAGCGGCTCGGGCTTCTTCCGCAGACACCGGTTGCGCCCGATGGAAT
CACCGTCGCTGACCTGGTAGGGCGAGGCCGCACGCCTTACCAGGGAATTTTGGGTAGGTGGACTGCGTCCGACTACGACA
TCGTCGCCGAAGCGATGGCGTCCACCCAGGTGGCGGAATTGGCAGATCGGAGCATCGAAGAGCTTTCCGGCGGCCAGCGG
CAGCGCGTATGGATTGCGATGGCGCTCGCGCAGCAGACCGACGTATTGCTTCTCGACGAACCGACCACCTACCTCGACTT
GAAACACCAGTTAGAAGTCCTGGATTTACTGACCGACCTCAATCAACGTCGTGGCACCACCATCATCATGGTGCTGCACG
ACCTGAATTTGGCCGCCCGCTACTCCGACAACCTCGTAGCTATGCGCGATGGTCGCTTGCATTCGGTGGGCAGGCCCGTC
GACGTGCTCACGCAAGACCTCACCCGCGAGGCGTTTGACCTCGAATCGCTCGTTATTACCGATCCTGTGTCAGGGCTGCC
GACGGTGACTCCCATCGGCCGTCATCACACGCAACTAGTTCACTAG

Protein sequence : 
MLLSLLPGTKELLTLSAQLTSRSLSSGYGADPIVKDVTLSFESGKITSIVGPNGCGKSTFLRTLARLIRPTAGSVELDGK
PLGAYSSRELAKRLGLLPQTPVAPDGITVADLVGRGRTPYQGILGRWTASDYDIVAEAMASTQVAELADRSIEELSGGQR
QRVWIAMALAQQTDVLLLDEPTTYLDLKHQLEVLDLLTDLNQRRGTTIIMVLHDLNLAARYSDNLVAMRDGRLHSVGRPV
DVLTQDLTREAFDLESLVITDPVSGLPTVTPIGRHHTQLVH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 8e-67 54
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 6e-69 51
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 6e-69 51
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 3e-55 49
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 3e-56 47
ciuD YP_005681255.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 4e-57 45
ciuD YP_005683346.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 4e-57 45
ciuD YP_003783391.1 iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 4e-57 45
ciuD YP_005685432.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 4e-57 45
CDCE8392_1767 YP_005134301.1 iron complex transport system ATP-binding protein Virulence Not named Protein 8e-35 42
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 2e-52 41
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 2e-52 41
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 2e-52 41
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 2e-52 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
irp1D YP_005143645.1 Fe3+-siderophore ABC transporter ATP-binding protein BAC0164 Protein 2e-55 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
irp1D YP_005143645.1 Fe3+-siderophore ABC transporter ATP-binding protein VFG1042 Protein 2e-55 49
irp1D YP_005143645.1 Fe3+-siderophore ABC transporter ATP-binding protein VFG0925 Protein 6e-64 49