Gene Information

Name : aldA (CDPW8_2073)
Accession : YP_005143621.1
Strain : Corynebacterium diphtheriae PW8
Genome accession: NC_016789
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2186411 - 2187931 bp
Length : 1521 bp
Strand : -
Note : -

DNA sequence :
ATGACTATTTATGCATATCCAGGAATGCCAGGTGCTGTAGCCAACTACAAGAAGCGCTATGACAACTACATCGGCGGCCA
ATGGGTTCCGCCGGTAGGTGGCGAATACTTGGACAACATCACCCCAGTCACCGGTGAAGTGTTCTGTCAAGTGGCACGAG
GAACCGCTGCCGACGTGGAAAAGGCCTTGGATGCAGCGCATGATGCAGCAAAAACATGGGGTCATAGCTCGCCGGCTGAG
CGCGCACTTATTCTGCACCGCATTGCCGATCGCATGGAAGAACATCTCGAAGAAATCGCCGTTGCCGAAACATGGGATAA
CGGCAAGGCGGTACGTGAAACTCTCGCCGCCGATATTCCACTGGCCATCGACCACTTCCGCTACTTTGCCGGTGCAATCC
GTGCCCAAGAATCGCGAACCTCGCAGATCGACCACAACACGGTGGCCTACCACTTCCATGAGCCCATCGGCGTAGTCGGT
CAGATCATTCCGTGGAACTTCCCACTGCTCATGGCTGCATGGAAGATCGCCCCAGCTCTTGCTGCGGGTAACACGATTGT
GTTGAAGCCCGCGGAGCAAACTCCTGCGTCCATTCTGTTCTGGATCGACATTGTTGGCGATCTGCTTCCTAACGGTGTGC
TCAACATCGTCAACGGCCTCGGCGAGGAGGCTGGCGTGGCGCTATCCTCTTCCAACCGCATTGGCAAGATTGCCTTTACT
GGTTCCACGCAGGTGGGCAAGATTATCAACCGTGCTGCCGCCGACAAGATCATCCCCGTCACCTTGGAGCTAGGCGGTAA
GTCGCCGTCGATCTTCTTCGCGGACATCATGGATTACGACGACCCCTTCCGTGAGAAGTGCATTGAGGGCCTTGCCATGT
TCGCACTCAATCAGGGTGAGGTATGTACCTGCCCGTCGCGTGCGTTGGTGCATGAGTCCATTGCGGACGAGTTCCTTGAG
CTGGGTGTCCAACGTGTGAAGAACATCAAGCTCGGCAACCCGCTGGACACGGAAACCATGATGGGTGCCCAGGCTTCCAT
TGAACAAATGGATAAGATCAGTGGCTACCTCGATATTGGCCCGAAGGAGGGCGCTAAGGTGCTCACCGGTGGTCACGTGA
ACAAGATCGACGGTTTGGAAAATGGCTACTATATCGAGCCCACGGTGTTTAAGGGCACGAATGACATGACCATTTTCCGT
GAGGAAATCTTCGGCCCAGTGCTTTCGGTTGCTACCTTCAAGGATTTTGATGAGGCAATCCGCATTGCTAATGACACCAA
CTACGGCCTGGGCGCTGGTGTGTGGACTCGCCATCAGAACACTGCGTATCGTGCCGGACGCGCCATCCAAGCTGGTCGCG
TGTGGGTGAATCAATACCACAATTACCCAGCGCACGCAGCATTCGGAGGCTATAAGGAGTCCGGAATTGGGCGTGAGAAT
CACCTCATGATGTTGGATCACTACCAGCAGACAAAGAACCTTCTTGTCTCGTATGATGAGAATCCAACAGGCTTATTTTA
A

Protein sequence :
MTIYAYPGMPGAVANYKKRYDNYIGGQWVPPVGGEYLDNITPVTGEVFCQVARGTAADVEKALDAAHDAAKTWGHSSPAE
RALILHRIADRMEEHLEEIAVAETWDNGKAVRETLAADIPLAIDHFRYFAGAIRAQESRTSQIDHNTVAYHFHEPIGVVG
QIIPWNFPLLMAAWKIAPALAAGNTIVLKPAEQTPASILFWIDIVGDLLPNGVLNIVNGLGEEAGVALSSSNRIGKIAFT
GSTQVGKIINRAAADKIIPVTLELGGKSPSIFFADIMDYDDPFREKCIEGLAMFALNQGEVCTCPSRALVHESIADEFLE
LGVQRVKNIKLGNPLDTETMMGAQASIEQMDKISGYLDIGPKEGAKVLTGGHVNKIDGLENGYYIEPTVFKGTNDMTIFR
EEIFGPVLSVATFKDFDEAIRIANDTNYGLGAGVWTRHQNTAYRAGRAIQAGRVWVNQYHNYPAHAAFGGYKESGIGREN
HLMMLDHYQQTKNLLVSYDENPTGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-146 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-154 62
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-154 62
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-154 62
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-154 62

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldA YP_005143621.1 aldehyde dehydrogenase VFG0082 Protein 2e-146 63