Gene Information

Name : frgC (CDHC04_0973)
Accession : YP_005140284.1
Strain : Corynebacterium diphtheriae HC04
Genome accession: NC_016788
Putative virulence/resistance : Virulence
Product : iron-siderophore uptake system ATP-binding protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1010672 - 1011493 bp
Length : 822 bp
Strand : -
Note : -

DNA sequence : 
ATGACCAGCACTTCCCCCATTCTTCGTACCGATTCCGTCACATTGGCGTGGGATAAGCACACAGTAAGTACTGATCTCAC
GGTCGAGGTGCCGCAAGGACAATTCACGGCCATCATTGGGCCAAATGGTTGTGGAAAATCCACACTATTAAAAAGCTTCG
CCCGAATTCTTCAACCACACACTGGGCAAGTATATCTATGTGACAACCCGCTGGATTCTTTGCACACAAAATACATAGCC
CAACGTATAGCTTTGCTGCCACAAACAGCACTTGCACCAGCTGATATTACTGTCGAAGAACTCGTAGGCAGAGGTCGTTT
CCCCTACCAAACCCTTCTGCGACAGTGGTCAACTAAGGATGCTCAAGCAGTTGATTCCGCCCTCCTAGCAACCGGCACGG
CACAACTACGCCACCGCCGCGTTACTGAACTTTCTGGCGGCCAACGTCAACGAGTCTGGCTCGCAATGGTGCTGGCCCAA
AACACACCCGTAGTTCTCCTAGACGAGCCCACAACGTATCTCGATGTAGCCCACCAATACCAGCTTTTAGAGCTCGCCCG
AGCACTGCGACAACAGCTCGGACGAACTATTGTGACCGTCTTGCACGATCTACAACAGGCTGTTAGATATGCCGACCATC
TTATCGTGATGAAAGGTGGCGCAGTCTATGCTGAAGGCGCTCCAAGCAGCATCATGACACCACAATTGATTTCCGAGGTA
TTTGAAATCAATGTTGATGTTCATACCATCGACGATCATGTGGTGATCGTGCCCAAAACCATGCCTCAACCTGATGTATC
AGTCCTAGAAAATCTGCAATAG

Protein sequence : 
MTSTSPILRTDSVTLAWDKHTVSTDLTVEVPQGQFTAIIGPNGCGKSTLLKSFARILQPHTGQVYLCDNPLDSLHTKYIA
QRIALLPQTALAPADITVEELVGRGRFPYQTLLRQWSTKDAQAVDSALLATGTAQLRHRRVTELSGGQRQRVWLAMVLAQ
NTPVVLLDEPTTYLDVAHQYQLLELARALRQQLGRTIVTVLHDLQQAVRYADHLIVMKGGAVYAEGAPSSIMTPQLISEV
FEINVDVHTIDDHVVIVPKTMPQPDVSVLENLQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 4e-77 65
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 4e-77 65
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 5e-77 65
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 5e-77 65
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 2e-51 51
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 4e-51 45
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 3e-44 41
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 3e-44 41
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 5e-38 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
frgC YP_005140284.1 iron-siderophore uptake system ATP-binding protein BAC0164 Protein 1e-51 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
frgC YP_005140284.1 iron-siderophore uptake system ATP-binding protein VFG0925 Protein 3e-56 52
frgC YP_005140284.1 iron-siderophore uptake system ATP-binding protein VFG1042 Protein 9e-52 51