Gene Information

Name : frgC (CDHC01_0967)
Accession : YP_005135766.1
Strain : Corynebacterium diphtheriae HC01
Genome accession: NC_016786
Putative virulence/resistance : Virulence
Product : iron-siderophore uptake system ATP-binding component
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 985656 - 986477 bp
Length : 822 bp
Strand : -
Note : -

DNA sequence : 
ATGACCAGCACTTCCCCCATTCTTCGTACCAATTCCGTCACATTGGCGTGGGATAAGCACACAGTAAGTACTGACCTCAC
TGTCGAGGTGCCGCAAGGACAATTCACAGCCATCATTGGGCCAAATGGTTGTGGAAAATCCACACTATTAAAAAGCTTCG
CCCGAATTCTTCAACCACACACTGGGCAAGTGTATCTAGGTGACAACCCGCTGGATTCTTTGCACACAAAATACATAGCC
CAACGTATCGCTTTGCTGCCACAAACAGCACTTGCACCAGCTGATATTACTGTCGAAGAACTCGTAGGCAGAGGTCGTTT
CCCCTACCAAACCCTTCTGCGACAGTGGTCAGCTAGGGATGCTCAAGCAGTTGATTCCGCCCTCCTAGCAACCGGCACGG
CACAACTACGCCACCGCCGCGTTACTGAACTTTCTGGCGGCCAACGTCAACGAGTCTGGCTCGCAATGGTGCTGGCCCAA
AACACACCCGTAGTTCTCCTAGACGAGCCCACAACGTATCTCGATGTAGCCCACCAATACCAGCTTTTGGAGCTCGCCCG
AGCACTGCGGCAACAGCTCGGACGAACAATTGTGACCGTCTTGCACGATTTACAACAGGCTGTTAGATATGCCGACCATC
TTATTGTGATGAAAGATGGCGCAGTCTATGCCGAAGGCGCTCCAAGCAGCATCATGACACCACAATTGATTTCCGAGGTA
TTTGAAATCAATGTTGATGTTCATACCATCGACGATCATGTGGTGATCGTGCCCAAAACCATGCCTCAACCTGATGTATC
AGTCCTAGAAAATCTGCAATAG

Protein sequence : 
MTSTSPILRTNSVTLAWDKHTVSTDLTVEVPQGQFTAIIGPNGCGKSTLLKSFARILQPHTGQVYLGDNPLDSLHTKYIA
QRIALLPQTALAPADITVEELVGRGRFPYQTLLRQWSARDAQAVDSALLATGTAQLRHRRVTELSGGQRQRVWLAMVLAQ
NTPVVLLDEPTTYLDVAHQYQLLELARALRQQLGRTIVTVLHDLQQAVRYADHLIVMKDGAVYAEGAPSSIMTPQLISEV
FEINVDVHTIDDHVVIVPKTMPQPDVSVLENLQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 8e-78 65
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 8e-78 65
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 8e-78 65
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 8e-78 65
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 6e-53 52
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 5e-52 46
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 2e-45 41
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 2e-45 41
ciuD YP_005681255.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 2e-43 41
ciuD YP_005683346.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 2e-43 41
ciuD YP_003783391.1 iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 2e-43 41
ciuD YP_005685432.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 2e-43 41
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 1e-38 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
frgC YP_005135766.1 iron-siderophore uptake system ATP-binding component BAC0164 Protein 4e-53 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
frgC YP_005135766.1 iron-siderophore uptake system ATP-binding component VFG1042 Protein 4e-53 52
frgC YP_005135766.1 iron-siderophore uptake system ATP-binding component VFG0925 Protein 6e-57 52