Gene Information

Name : guaA (CDHC01_0532)
Accession : YP_005135333.1
Strain : Corynebacterium diphtheriae HC01
Genome accession: NC_016786
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 520692 - 522308 bp
Length : 1617 bp
Strand : +
Note : GMP synthase, PP-ATPase domain/subunit

DNA sequence :
GTGAGGGATTATGCGGGCACGTCAGGTAAGATTTTGGCCGTGACGCAGCAAACTTCCCAAAAACACAATCCAGTCTTGGT
TGTAGACTTTGGCGCGCAATACGCCCAGCTGATCGCTCGGCGCGTGCGCGAAGCCAACATCTACTCCGAGGTCGTCCCAC
ATACCGCCACGGTTGAAGAGATCAAGGCCAAAAACCCGGCGGCGTTAATCCTGTCCGGTGGCCCATCATCGGTTTACGCC
GACGGCGCACCATCGCTTGACCCACAGGTTCTCGAACTCGGCATCCCCGTCTTCGGCATCTGCTACGGCTTCCAAGCTAT
GACCCACGCCCTAGGCGGCACCGTGGCCAACACCGGCAACCGTGAATACGGTCGCACCGAAATGACCGTCGATGGCGGCA
TTCTCCACGCTGACCTCGAAGAAACCCACAAAGTATGGATGAGCCACGGCGACGCTGTCTCCGTTGCACCAGAGGGATTC
GTTGTCACCGCCCACTCCGAAGGTGCACCCGTCGCAGCCTTCGAATGCGCCGAAAAGCGCATGGCAGGCGTGCAATACCA
CCCAGAGGTTCTGCACTCGCCACACGGCCAAGAAGTCATGGTGCGCTTCCTCACCGAGATCGCCGGCCTTGAGCAAAACT
GGACCGCAGCCAACATCGCCGAAGAGCTTATCGACGCAGTCCGCGCACAGGTCGGACCAGAAGGCCGCGCTATCTGTGGT
CTTTCCGGTGGTGTTGACTCTGCAGTCGCAGCAGCACTCGTCCAGCGCGCCATCGGCGACCGCCTCACCTGCGTATTCGT
CGATCATGGCTTGCTGCGTGCAGGCGAACGCGAACAGGTCCAAACCGATTTCGTCGCCGCAACCGGCGCAAAACTCGTCA
CCGTTGACGAGCGAGAAGCATTCCTGAACAAGCTCGCAGGTGTCACCGAACCAGAAGCTAAGCGCAAAGCCATCGGCGCA
GAATTCATCCGCTCCTTCGAACGCGCAGTCGCCGGCATTCTCGACGACGCCCCCGAAGGCTCCACCGTGGACTTTCTCGT
CCAAGGCACCCTCTACCCAGACGTTGTAGAATCCGGCGGCGGCTCTGGTACCGCCAACATCAAGAGCCACCACAACGTGG
GTGGCCTGCCCGACGACGTAGAATTCCAACTCGTCGAACCACTACGCTTACTGTTCAAAGACGAAGTACGCGCAGTGGGT
CGCGAACTCGGTCTGCCTGAAGAAATCGTCAACCGCCAGCCCTTCCCAGGCCCCGGCCTCGGCATCCGCATCATCGGCGA
AGTCACCGAAGAGCGCCTCGAAACACTACGCGCAGCCGACCTCATCGCCCGCACCGAGCTGACCGCAGCTGGCCTCGACA
GCGAAATCTGGCAGTGCCCAGTAGTTTTGCTTGCCGACGTCCGCTCCGTCGGCGTCCAAGGCGACGGCCGCACTTACGGA
CATCCCATCGTCCTACGCCCCGTCTCCTCCGAAGACGCCATGACCGCAGACTGGACCCGACTGCCCTACGACGTGCTCGA
GAAAATCTCCACACGTATCACCAACGAGGTCTCAGACGTCAACCGCGTCGTCCTCGACTGCACCTCCAAGCCACCAGGAA
CCATCGAGTGGGAATAA

Protein sequence :
MRDYAGTSGKILAVTQQTSQKHNPVLVVDFGAQYAQLIARRVREANIYSEVVPHTATVEEIKAKNPAALILSGGPSSVYA
DGAPSLDPQVLELGIPVFGICYGFQAMTHALGGTVANTGNREYGRTEMTVDGGILHADLEETHKVWMSHGDAVSVAPEGF
VVTAHSEGAPVAAFECAEKRMAGVQYHPEVLHSPHGQEVMVRFLTEIAGLEQNWTAANIAEELIDAVRAQVGPEGRAICG
LSGGVDSAVAAALVQRAIGDRLTCVFVDHGLLRAGEREQVQTDFVAATGAKLVTVDEREAFLNKLAGVTEPEAKRKAIGA
EFIRSFERAVAGILDDAPEGSTVDFLVQGTLYPDVVESGGGSGTANIKSHHNVGGLPDDVEFQLVEPLRLLFKDEVRAVG
RELGLPEEIVNRQPFPGPGLGIRIIGEVTEERLETLRAADLIARTELTAAGLDSEIWQCPVVLLADVRSVGVQGDGRTYG
HPIVLRPVSSEDAMTADWTRLPYDVLEKISTRITNEVSDVNRVVLDCTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 0.0 99
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-132 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-132 51
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-132 51