Gene Information

Name : CDHC01_2201 (CDHC01_2201)
Accession : YP_005136990.1
Strain : Corynebacterium diphtheriae HC01
Genome accession: NC_016786
Putative virulence/resistance : Unknown
Product : putative type I restriction/modification system DNA methylase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2357159 - 2358766 bp
Length : 1608 bp
Strand : -
Note : -

DNA sequence :
ATGGTACGGAAGAAGAAGGAAGTGGCGCAGGTCCCTTCCACCTCTAAGGAAATCAAGGACACATTGTGGAAGTCCGCGGA
TAAGCTTCGCGGTTCTATGGATGCGTCGCAGTACAAGGATGTTGCTCTGGGGCTGGTGTTCCTAAAGTATGTATCGGATT
CCTTTGAGGAACGTCAGAAGGAAATCCGCGCGGAGCTAGAAGGCAAGGGCTTCGATGAGGAATACATCCTAGAAGATCTT
GCCGACGTTGACGCTTACACCAGCGAGAATGTTTTTTGGGTGGCGTCGAATGCCCGTTGGGACTTTCTAAAGAAGTATTC
CAAGGGCATGGATCTGGAAGGAAAACACAAGTCTATCGGCAAGTTGATCGATGAGGCTATGCAGCAGCTCATGGCGGATA
ACGAATCGCTACTGGGCACGCTGCCGCAGATTTATGGCAAGGACAATATCGACCAGCGCCGTCTCGGTGAATTAGTGGAC
CTGTTTAGCTCTACGTATTTTGCCAGCACTAAGGATAAGAAGGCCCGCGACCTGCTTGGGGAGGTTTACGAGTACTTTCT
GGATAAGTTCGCCAAGGCCGAGGGTAAGAGGGGTGGCGAGTTTTATACGCCGCAGCCGGTCGTGCGGACGTTGGTAGAAA
TCCTTGAGCCGACTGAGGGGCGTGTGTATGACCCATGCTGTGGTTCGGGTGGCATGTTTGTGCAGGCGGAAAAGTTCTTG
GAGGTTACCAAGCGTGACCGCAGCAACATTGCGGTTTATGGCCAAGAACTCAATGAGCGTACTTGGCGAATGGCGAAGAT
GAACTTGGCTATTCACGCCATTAGTTCGTCCGGTTTGGGTGAGCGTTGGGGTGACACGTTTGCTCGCGATATTCATGCGG
GCACCAAGATGGACTACATCATGGCTAATCCGCCGTTCAACATTAAGGATTGGATTTGCAACGAGGAGGACGCCCGTTGG
AAGTACGGTGTGCCTCCGGCGAAGAATGCGAACTTTGCGTGGATGCAGCACATTATTTCGAAGCTGAAGGATCACGGCGA
GGCTGGTGTTGTGATGGCGAATGGCACGATGACGTCGCAAAGCTCTGGTGAGGGCGAGATCCGTAAAAACATGGTGGAAG
ATGATGTTGTTTCGTGTGTGATTGCGTTGCCGGCGCAGTTGTTCCGTGGCACGGGCATTCCGGTGTGCGTGTGGTTTTTT
GCTAAGGATAAGTCGGCGGGTGCTGGTGGCAGCGTTGATCGCCGTGGTGAGGTGTTGCTTATCGACGCCCGCCAGCTCGG
CCACATGATCGACCGCACGGAGCGGGCGTTTAGTGATGAGGACATCGCCAAGATTGCTAATGCGTTCCGAACCTGGCGTG
GGCGTAAGTCCGCGGAGGGGGAGTACGAGGATGAGGCGGGATTCTGTAAGTCCGCGACGATTGAGGAGATCCGCGAAGCT
GGCTATGCGCTAACACCTGGCCGCTACGTGGGCATGCCTGAGGCCGAAGAAGACGATGAGCCTATCGACGAAAAGATCGC
ACGTCTAACCGCAGAATTGACTGCTGCATTGGACGAGTCTGCACGTTTGGACGCTGTCGTTCGCGAGCAGCTGGGGAGGT
TGAAGTGA

Protein sequence :
MVRKKKEVAQVPSTSKEIKDTLWKSADKLRGSMDASQYKDVALGLVFLKYVSDSFEERQKEIRAELEGKGFDEEYILEDL
ADVDAYTSENVFWVASNARWDFLKKYSKGMDLEGKHKSIGKLIDEAMQQLMADNESLLGTLPQIYGKDNIDQRRLGELVD
LFSSTYFASTKDKKARDLLGEVYEYFLDKFAKAEGKRGGEFYTPQPVVRTLVEILEPTEGRVYDPCCGSGGMFVQAEKFL
EVTKRDRSNIAVYGQELNERTWRMAKMNLAIHAISSSGLGERWGDTFARDIHAGTKMDYIMANPPFNIKDWICNEEDARW
KYGVPPAKNANFAWMQHIISKLKDHGEAGVVMANGTMTSQSSGEGEIRKNMVEDDVVSCVIALPAQLFRGTGIPVCVWFF
AKDKSAGAGGSVDRRGEVLLIDARQLGHMIDRTERAFSDEDIAKIANAFRTWRGRKSAEGEYEDEAGFCKSATIEEIREA
GYALTPGRYVGMPEAEEDDEPIDEKIARLTAELTAALDESARLDAVVREQLGRLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 3e-126 50
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 1e-126 49
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 4e-126 49
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 3e-110 45