Gene Information

Name : irp1D (CDHC01_2029)
Accession : YP_005136818.1
Strain : Corynebacterium diphtheriae HC01
Genome accession: NC_016786
Putative virulence/resistance : Virulence
Product : Fe3+-siderophore ABC transporter ATP-binding protein
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.34
Position : 2152564 - 2153367 bp
Length : 804 bp
Strand : -
Note : ABC-type sugar transport systems, ATPase components

DNA sequence : 
TTGTCCGCTCAACTTACTTCCCGTTCTCTTTCTTCTGGGTATGGGGCAGATCCCATTGTGAAAGATGTAACCCTGTCGTT
TGAGTCCGGCAAGATTACGTCGATTGTCGGGCCGAATGGTTGCGGCAAGTCAACGTTTCTGCGGACACTAGCGAGGTTGA
TTCGGCCTACAGCCGGTTCCGTTGAGCTGAATGGCAAGCCACTGGGAGCATATTCTTCGCGCGAGTTGGCAAAGCGGCTC
GGGCTTCTTCCGCAGACACCGGTTGCGCCCGATGGAATCACCGTCGCTGACCTGGTAGGGCGAGGCCGCACGCCTTACCA
AGGAATTTTGGGTAGGTGGACTGCGTCCGACTACGACATCGTCGCCGAAGCGATGGCGTCCACCCAGGTGGCGGAATTGG
CAGATCGGAGCATCGAAGAGCTTTCCGGCGGCCAGCGGCAGCGCGTATGGATTGCGATGGCGCTCGCGCAGCAGACCGAC
GTATTGCTTCTCGACGAACCGACCACCTACCTCGACTTGAAACACCAGTTAGAAGTCCTGGATTTACTGACCGACCTCAA
TCAACGTCGTGGCACCACCATCATCATGGTGCTGCACGACCTGAATTTGGCCGCCCGCTACTCCGACAACCTCGTAGCTA
TGCGCGATGGTCGCTTGCATTCGGTGGGCAGGCCCGTCGACGTGCTCACGCAAGACCTCACCCGCGAGGCGTTTGACCTC
GAATCGCTCGTTATTACCGATCCTGTGTCAGGACTGCCGACGGTGACTCCCATCGGCCGTCATCACACGCAACTAGTTCA
CTAG

Protein sequence : 
MSAQLTSRSLSSGYGADPIVKDVTLSFESGKITSIVGPNGCGKSTFLRTLARLIRPTAGSVELNGKPLGAYSSRELAKRL
GLLPQTPVAPDGITVADLVGRGRTPYQGILGRWTASDYDIVAEAMASTQVAELADRSIEELSGGQRQRVWIAMALAQQTD
VLLLDEPTTYLDLKHQLEVLDLLTDLNQRRGTTIIMVLHDLNLAARYSDNLVAMRDGRLHSVGRPVDVLTQDLTREAFDL
ESLVITDPVSGLPTVTPIGRHHTQLVH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 1e-66 53
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 5e-69 50
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 5e-69 50
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 2e-55 49
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 3e-56 47
ciuD YP_005681255.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 3e-57 45
ciuD YP_005683346.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 3e-57 45
ciuD YP_003783391.1 iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 3e-57 45
ciuD YP_005685432.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 3e-57 45
CDCE8392_1767 YP_005134301.1 iron complex transport system ATP-binding protein Virulence Not named Protein 1e-34 42
phuC YP_005682167.1 Iron(III) dicitrate transport permease-like protein yusV Virulence PiCp 7 Protein 9e-32 41
phuC YP_005684259.1 Iron(III) dicitrate transport permease-like protein yusV Virulence PiCp 7 Protein 9e-32 41
cpfrc_01918 YP_003784318.1 hypothetical protein Not tested PiCp 7 Protein 9e-32 41
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 2e-52 41
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 2e-52 41
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 2e-52 41
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 2e-52 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
irp1D YP_005136818.1 Fe3+-siderophore ABC transporter ATP-binding protein BAC0164 Protein 1e-55 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
irp1D YP_005136818.1 Fe3+-siderophore ABC transporter ATP-binding protein VFG1042 Protein 1e-55 49
irp1D YP_005136818.1 Fe3+-siderophore ABC transporter ATP-binding protein VFG0925 Protein 8e-64 49