Gene Information

Name : clpC (CDCE8392_1852)
Accession : YP_005134386.1
Strain : Corynebacterium diphtheriae CDCE 8392
Genome accession: NC_016785
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1950954 - 1953590 bp
Length : 2637 bp
Strand : -
Note : -

DNA sequence :
ATGTTCGAGCGGTTTACCGATCGTGCACGTCGCGTTATCGTTCTGGCACAGGAAGAAGCGCGCGGCCTCAATCACAATTA
CATCGGCACCGAGCACATCCTGCTCGGACTTATTCACGAGGGTGAGGGCGTGGCCGCTAAGGCGCTCGAGTCCATGGGCA
TCTCCCTTGAAGCGGTACGCCAAGAGGTAGAAGAAATCATCGGCCACGGCTCCGAGCCACCAGCTGGCCACATTCCTTTT
ACTCCACGTGCCAAGAAGGTACTTGAGCTCTCCTTGCGTGAGGGTCTGCAGATGGGACATAAGTACATCGGTACTGAGTT
CCTGCTGCTCGGCCTTATCCGTGAGGGCGATGGCGTAGCCGCACAAGTTTTGGTCAAGCTCGGCGCTGACCTGCCCCGTG
TACGCCAGCAGGTTATTCAGCTTCTTTCCGGCTACGAGGGTGGCGAAAGCCCAGAAAACAATAACGACGGCGAGGCTGTG
GGTGCTGGTACTGGCGCTGGCCGTGCTGGCCGCGGTGGTGGCGCAGGCGAGCGCTCCAACTCCTTGGTTTTGGACCAGTT
TGGTCGCAACCTCACCCAGGCTGCTAAGGAAGGCAAGCTGGATCCTGTGGTGGGGCGTGAGCAGGAAATTGAGCGCATCA
TGCAGGTGCTCTCACGTCGTACCAAGAACAACCCAGTTCTTATCGGAGAGCCAGGTGTTGGTAAGACCGCTGTTGTAGAA
GGCCTAGCTCTAGACATCGTTAATGGAAAGGTGCCAGAAACGCTGAAAGACAAGCAGGTTTACTCTCTTGACCTCGGCTC
CTTGGTGGCAGGTTCGCGCTACCGTGGTGACTTCGAAGAGCGCCTGAAGAAGGTCCTCAAGGAGATCAATCAGCGTGGCG
ACATCATCTTGTTCATCGATGAGATCCACACCCTCGTCGGTGCCGGTGCCGCAGAAGGCGCTATCGACGCTGCCAGCTTG
CTCAAACCTAAACTGGCTCGTGGTGAGCTACAGACCATCGGTGCTACCACTTTGGACGAGTACCGCAAGCACATCGAAAA
GGACGCCGCACTTGAGCGTCGTTTCCAGCCAGTGCAGGTTCCAGAGCCTTCCGTCGATATGACCATCGAGATCCTCAAGG
GTCTACGTGACCGCTACGAGGCACACCACCGCGTCTCCATCACTGATGGGGCTCTCGCAGCAGCAGCACAGCTGTCCGAT
CGCTACATCAACGATCGCTTCTTGCCAGATAAGGCTGTTGACCTTATCGACGAAGCCGGCGCACGCATGCGTATCAAGCG
CATGACCGCACCGGAATCCATCCGCAAGGTTGACGATCAGATAGCGGAAGTCCGTCGTGAGAAGGAAGCCGCAATCGATG
CCCAAGACTTTGAAAAGGCCGCAGGCCTGCGCGACACCGAGCGCAAGTTAGGCGAAGAGCGCGCTGAGAAAGAAAAGCAG
TGGCGCTCCGGCGACCTAGAAGACATCGCAGAAGTCGGCGAGGAGCAAATCGCTGAGGTTCTGGGTAACTGGACTGGCAT
CCCAGTGTTCAAGCTGACCGAGGAAGAATCCTCCCGTCTGCTGCACATGGAAGAGGAGCTACACACGCGCATCATCGGCC
AAGACGATGCCGTCAAGAGTGTTTCTCGCGCCATCCGCCGCACCCGCGCTGGCCTCAAGGACCCACGCCGTCCTTCCGGC
TCCTTCATCTTCGCCGGCCCATCTGGTGTGGGTAAGACCGAGCTATCCAAGTCGCTGGCCAACTTCCTGTTCGGCGACGA
CGACGCCCTAATCCAGATCGACATGGGCGAGTTCCACGACCGCTTCACCGCATCCCGTCTGTTCGGTGCCCCTCCAGGAT
ATGTGGGTTACGACGAGGGCGGTCAGCTCACCGAGAAGGTCCGCCGCAAGCCATTCTCCGTGGTGCTTTTCGACGAAATC
GAAAAGGCCCACAAGGAGATCTACAACACCTTGCTGCAGGTCCTCGAAGAAGGTCGCCTCACCGACGGCCAAGGCCGCGT
TGTGGACTTCAAGAACACCGTGCTGATCTTCACCTCCAACCTGGGTACCCAAGACATCTCTAAGGCTGTGGGCATGGGCT
TTAGCTCTGTCGGCGAGCACGATGCCGACGGTCAGTACGACCGCATGAAGCAGAAGGTCAACGACGAGCTGAAGAAGCAC
TTCCGCCCTGAGTTCCTCAACCGTATCGACGAAATCGTGGTCTTCCACCAGCTCACCCAAGAGCAGATCGTCGAAATGGT
GGACCTGCTCATCGGACGCGTATCCAAGGCACTTGCTCAAAAAGACATGGGCATCGAGCTTACGGAGAAGGCCAAGAACC
TGCTGGCAAAGCGTGGATTCGATCCAGTACTGGGTGCACGACCATTGCGTCGCACCATCCAGCGCGAGATCGAAGACGTA
CTCTCCGAGAAGATCCTCTTCGGTGAGGTCGGCGCTGGTGAGATCGTCACCGTGGATGTTGAAGGCTGGGACGGCGAATC
CAAGGAAACCGACAAGGCTTCCTTCACCTTCACCCCACGCGTGAAGCCGCTGCCAGACGAGTTCGAAGAGGCAACCCCAT
CTGAGGAAGCTCAAGAAGCAGTGATTAACGCTGCTGAGACTGAGGTTCCAGAAGAAGAAGCCAACATCGAGAACTAA

Protein sequence :
MFERFTDRARRVIVLAQEEARGLNHNYIGTEHILLGLIHEGEGVAAKALESMGISLEAVRQEVEEIIGHGSEPPAGHIPF
TPRAKKVLELSLREGLQMGHKYIGTEFLLLGLIREGDGVAAQVLVKLGADLPRVRQQVIQLLSGYEGGESPENNNDGEAV
GAGTGAGRAGRGGGAGERSNSLVLDQFGRNLTQAAKEGKLDPVVGREQEIERIMQVLSRRTKNNPVLIGEPGVGKTAVVE
GLALDIVNGKVPETLKDKQVYSLDLGSLVAGSRYRGDFEERLKKVLKEINQRGDIILFIDEIHTLVGAGAAEGAIDAASL
LKPKLARGELQTIGATTLDEYRKHIEKDAALERRFQPVQVPEPSVDMTIEILKGLRDRYEAHHRVSITDGALAAAAQLSD
RYINDRFLPDKAVDLIDEAGARMRIKRMTAPESIRKVDDQIAEVRREKEAAIDAQDFEKAAGLRDTERKLGEERAEKEKQ
WRSGDLEDIAEVGEEQIAEVLGNWTGIPVFKLTEEESSRLLHMEEELHTRIIGQDDAVKSVSRAIRRTRAGLKDPRRPSG
SFIFAGPSGVGKTELSKSLANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYDEGGQLTEKVRRKPFSVVLFDEI
EKAHKEIYNTLLQVLEEGRLTDGQGRVVDFKNTVLIFTSNLGTQDISKAVGMGFSSVGEHDADGQYDRMKQKVNDELKKH
FRPEFLNRIDEIVVFHQLTQEQIVEMVDLLIGRVSKALAQKDMGIELTEKAKNLLAKRGFDPVLGARPLRRTIQREIEDV
LSEKILFGEVGAGEIVTVDVEGWDGESKETDKASFTFTPRVKPLPDEFEEATPSEEAQEAVINAAETEVPEEEANIEN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 99
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 3e-98 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_005134386.1 ATP-dependent Clp protease ATP-binding subunit VFG0079 Protein 0.0 58
clpC YP_005134386.1 ATP-dependent Clp protease ATP-binding subunit VFG0080 Protein 1e-150 50