Gene Information

Name : aldA (CD241_2008)
Accession : YP_005126263.1
Strain : Corynebacterium diphtheriae 241
Genome accession: NC_016782
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2120107 - 2121627 bp
Length : 1521 bp
Strand : -
Note : -

DNA sequence :
ATGGCTGTTTATGCATATCCAGGAACGCCAGATGCCGTAGCCAACTACAAGAATCGCTACGACAACTACATCGGCGGCCA
GTGGGTACCACCGGTGGGTGGTGAATACCTCGATAACATCACACCAGTTACTGGCGAAGTGTTCTGCCAAGTGGCGCGAG
GAACTGCTGCTGATGTGGAAAAAGCCTTGGATGCAGCGCATCATGCAGCAAAAACATGGGGCCACAGTTCACCGGCCGAG
CGTGCACTCATCCTGCACCGCATTGCCGATCGCATGGAAGAGCATCTCGAAGAAATCGCCGTTGCCGAAACATGGGACAA
CGGCAAGGCTGTGCGTGAGACGCTCGCCGCCGACATTCCACTGGCCATCGACCACTTCCGCTACTTTGCCGGTGCAATCC
GTGCCCAAGAATCACGAACCTCGCAGATCGACCACAACACGGTGGCCTACCACTTCCATGAGCCCATCGGCGTAGTCGGT
CAGATCATTCCGTGGAACTTCCCACTGCTCATGGCCGCATGGAAGATCGCTCCAGCTCTTGCTGCGGGTAACACGATTGT
GTTGAAGCCTGCGGAGCAAACCCCTGCGTCCATCCTGTTCTGGATCGACATTGTGGGTGACTTGCTTCCTGATGGCGTGC
TCAACATCGTCAACGGTCTGGGTGAGGAAGCTGGTGTGGCGCTATCCTCCTCCAACCGTATTGGCAAGATTGCCTTTACT
GGTTCCACACAGGTGGGCAAGATTATCAATCGTGCCGCTGCCGACAAGATCATCCCCGTCACCTTGGAGCTAGGCGGTAA
GTCGCCGTCGATCTTCTTCGCGGACATCATGGATTACGACGACCCCTTCCGTGAGAAGTGCATTGAGGGCCTTGCTATGT
TCGCACTCAATCAGGGTGAGGTATGTACCTGCCCGTCGCGTGCGTTGGTGCATGAGTCCATCGCGGACGAGTTCCTTGAG
CTGGGTGTCCAACGTGTGAAGAACATCAAGCTCGGCAACCCGCTGGACACGGAAACCATGATGGGTGCCCAAGCCTCCAT
GGAACAAATGGATAAGATCAGTGGCTACCTCGATATTGGCCCGAAGGAGGGCGCTGAGGTGCTCACCGGTGGCCACGTGA
ACAAGATTGACGGTTTGGAAAATGGCTACTATATCGAGCCCACGGTGTTTAAGGGCACGAATGACATGACCATTTTCCGT
GAGGAGATCTTCGGCCCAGTGCTTTCGGTTGCTACCTTCAAGGATTTTGATGAGGCAATCCGCATTGCTAATGACACCAA
CTATGGCCTCGGCGCTGGTGTGTGGACTCGCCATCAGAACACTGCGTATCGTGCCGGACGTGCCATCCAAGCTGGTCGCG
TGTGGGTGAATCAATACCATAATTACCCAGCGCACGCAGCATTCGGAGGCTATAAGGAGTCTGGAATTGGGCGTGAGAAT
CACCTCATGATGTTGGATCACTACCAGCAGACAAAGAACCTTCTTGTCTCGTATGATGAGAATCCAACAGGCTTATTTTA
A

Protein sequence :
MAVYAYPGTPDAVANYKNRYDNYIGGQWVPPVGGEYLDNITPVTGEVFCQVARGTAADVEKALDAAHHAAKTWGHSSPAE
RALILHRIADRMEEHLEEIAVAETWDNGKAVRETLAADIPLAIDHFRYFAGAIRAQESRTSQIDHNTVAYHFHEPIGVVG
QIIPWNFPLLMAAWKIAPALAAGNTIVLKPAEQTPASILFWIDIVGDLLPDGVLNIVNGLGEEAGVALSSSNRIGKIAFT
GSTQVGKIINRAAADKIIPVTLELGGKSPSIFFADIMDYDDPFREKCIEGLAMFALNQGEVCTCPSRALVHESIADEFLE
LGVQRVKNIKLGNPLDTETMMGAQASMEQMDKISGYLDIGPKEGAEVLTGGHVNKIDGLENGYYIEPTVFKGTNDMTIFR
EEIFGPVLSVATFKDFDEAIRIANDTNYGLGAGVWTRHQNTAYRAGRAIQAGRVWVNQYHNYPAHAAFGGYKESGIGREN
HLMMLDHYQQTKNLLVSYDENPTGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-147 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-155 62
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-155 62
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-155 62
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-155 62

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldA YP_005126263.1 aldehyde dehydrogenase VFG0082 Protein 3e-147 63