Gene Information

Name : clpC (CD241_1876)
Accession : YP_005126133.1
Strain : Corynebacterium diphtheriae 241
Genome accession: NC_016782
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1987306 - 1989942 bp
Length : 2637 bp
Strand : -
Note : -

DNA sequence :
ATGTTCGAGCGGTTTACCGATCGTGCACGTCGCGTTATCGTTCTGGCACAGGAAGAAGCGCGCGGCCTTAATCACAATTA
CATCGGCACCGAGCACATCCTGCTCGGACTTATTCACGAGGGCGAGGGCGTGGCCGCTAAGGCGCTCGAGTCCATGGGCA
TCTCCCTTGAAGCAGTACGCCAAGAGGTAGAAGAAATCATCGGCCACGGCTCCGAGCCACCAGCCGGCCACATTCCTTTT
ACTCCACGTGCCAAGAAGGTACTTGAGCTCTCCTTGCGTGAGGGTCTACAGATGGGACATAAGTACATCGGTACTGAGTT
CCTGCTGCTCGGCCTTATCCGCGAGGGCGACGGCGTAGCCGCACAAGTTTTGGTCAAGCTCGGCGCTGACCTGCCCCGTG
TACGCCAGCAGGTTATCCAGCTTCTTTCCGGCTACGAGGGTGGCGAAAGCCCAGAAAACAATAACGACGGCGAGGCTGTG
GGTGCTGGTACTGGCGCTGGCCGTGCTGGCCGCGGTGGTGGCGCAGGCGAGCGCTCCAACTCCTTGGTTTTGGACCAGTT
TGGTCGCAACCTCACCCAGGCTGCTAAGGAAGGCAAGCTGGATCCTGTGGTGGGTCGTGAGCAGGAAATTGAGCGCATCA
TGCAGGTGCTCTCACGTCGTACCAAGAACAACCCAGTTCTTATCGGAGAGCCAGGTGTTGGTAAGACCGCTGTTGTAGAA
GGCCTAGCTCTAGACATCGTTAATGGCAAGGTGCCAGAAACACTGAAAGACAAGCAGGTTTACTCTCTTGACCTCGGCTC
CTTGGTGGCAGGTTCGCGCTACCGTGGTGACTTCGAAGAGCGCCTGAAGAAGGTCCTCAAGGAGATCAACCAGCGTGGCG
ACATCATCTTGTTCATCGATGAGATCCACACCCTCGTCGGTGCCGGTGCCGCAGAAGGCGCTATCGACGCTGCCAGCTTG
CTCAAACCAAAACTGGCTCGTGGTGAGCTACAGACCATCGGTGCTACCACTTTGGACGAGTACCGCAAGCACATCGAAAA
GGACGCCGCACTTGAGCGTCGTTTCCAGCCAGTGCAGGTTCCAGAGCCTTCCGTCGATATGACCATCGAGATCCTCAAGG
GTCTACGCGACCGCTACGAGGCACACCACCGCGTCTCCATCACCGATGGGGCTCTCGCAGCAGCAGCACAGCTGTCCGAT
CGCTACATCAACGATCGCTTCTTGCCAGATAAGGCCGTTGACCTTATCGACGAAGCCGGCGCACGCATGCGTATCAAGCG
CATGACCGCACCGGAATCCATCCGCAAGGTAGACGATCAGATCGCGGAAGTCCGTCGTGAGAAGGAAGCCGCAATCGATG
CCCAAGACTTTGAAAAGGCCGCAGGCCTGCGCGACACCGAGCGCAAGTTAGGCGAAGAGCGTGCTGAGAAAGAAAAGCAG
TGGCGCTCCGGCGACCTAGAAGACATCGCCGAGGTCGGCGAGGAACAAATCGCTGAGGTCCTGGGTAACTGGACTGGTAT
CCCAGTGTTCAAGCTGACCGAGGAAGAATCCTCCCGTCTGCTGCACATGGAAGAGGAGCTACACAAGCGCATCATCGGCC
AAGACGATGCCGTCAAGAGTGTTTCTCGCGCCATCCGCCGCACCCGCGCTGGCCTCAAGGACCCACGCCGTCCTTCCGGC
TCCTTCATCTTCGCCGGCCCATCTGGTGTGGGTAAGACCGAGCTATCCAAGTCACTGGCCAACTTCCTGTTCGGCGACGA
CGACGCCCTAATCCAGATCGACATGGGCGAGTTCCACGACCGCTTCACCGCATCCCGTCTCTTCGGTGCCCCTCCAGGAT
ATGTGGGCTACGACGAGGGCGGTCAGCTCACCGAGAAGGTCCGCCGCAAGCCATTCTCCGTGGTGCTTTTCGACGAAATC
GAAAAGGCCCACAAGGAGATCTACAACACCTTGCTGCAGGTCCTCGAAGAAGGTCGCCTCACCGACGGCCAAGGCCGCGT
TGTGGACTTCAAGAACACCGTGCTGATCTTCACCTCCAACCTGGGTACCCAAGACATCTCTAAGGCTGTGGGCATGGGCT
TTAGCTCTGTCGGCGAGCACGACGCCGACGGTCAGTACGACCGCATGAAGCAGAAGGTCAACGACGAGCTGAAGAAGCAC
TTCCGCCCTGAGTTCCTCAACCGTATCGACGAAATCGTGGTATTTCACCAGCTCACCCAAGAGCAGATCGTCGAAATGGT
GGACCTGCTCATCGGACGCGTATCCAAGGCACTTGCTCAAAAAGACATGGGCATCGAGCTCACCGAAAAGGCCAAGAACC
TGCTGGCAAAGCGTGGATTCGATCCAGTACTGGGTGCACGACCATTGCGTCGCACCATCCAGCGCGAGATCGAAGACGTA
CTCTCCGAGAAGATCCTCTTCGGTGAGGTCGGCGCTGGTGAGATCGTCACCGTGGATGTTGAAGGCTGGGACGGCGAATC
CAAGGAAACCGACAAGGCTTCCTTCACCTTCACCCCACGCGTGAAGCCGCTGCCAGACGAGTTCGAAGAGGCAACCCCAT
CTGAGGAAGCTCAAGAAGCAGTGATTAACGCTGCTGAGACTGAGGTTCCAGAAGAAGAAGCCAACATCGAAAACTAA

Protein sequence :
MFERFTDRARRVIVLAQEEARGLNHNYIGTEHILLGLIHEGEGVAAKALESMGISLEAVRQEVEEIIGHGSEPPAGHIPF
TPRAKKVLELSLREGLQMGHKYIGTEFLLLGLIREGDGVAAQVLVKLGADLPRVRQQVIQLLSGYEGGESPENNNDGEAV
GAGTGAGRAGRGGGAGERSNSLVLDQFGRNLTQAAKEGKLDPVVGREQEIERIMQVLSRRTKNNPVLIGEPGVGKTAVVE
GLALDIVNGKVPETLKDKQVYSLDLGSLVAGSRYRGDFEERLKKVLKEINQRGDIILFIDEIHTLVGAGAAEGAIDAASL
LKPKLARGELQTIGATTLDEYRKHIEKDAALERRFQPVQVPEPSVDMTIEILKGLRDRYEAHHRVSITDGALAAAAQLSD
RYINDRFLPDKAVDLIDEAGARMRIKRMTAPESIRKVDDQIAEVRREKEAAIDAQDFEKAAGLRDTERKLGEERAEKEKQ
WRSGDLEDIAEVGEEQIAEVLGNWTGIPVFKLTEEESSRLLHMEEELHKRIIGQDDAVKSVSRAIRRTRAGLKDPRRPSG
SFIFAGPSGVGKTELSKSLANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYDEGGQLTEKVRRKPFSVVLFDEI
EKAHKEIYNTLLQVLEEGRLTDGQGRVVDFKNTVLIFTSNLGTQDISKAVGMGFSSVGEHDADGQYDRMKQKVNDELKKH
FRPEFLNRIDEIVVFHQLTQEQIVEMVDLLIGRVSKALAQKDMGIELTEKAKNLLAKRGFDPVLGARPLRRTIQREIEDV
LSEKILFGEVGAGEIVTVDVEGWDGESKETDKASFTFTPRVKPLPDEFEEATPSEEAQEAVINAAETEVPEEEANIEN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 99
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-98 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_005126133.1 ATP-dependent Clp protease ATP-binding subunit VFG0079 Protein 0.0 58
clpC YP_005126133.1 ATP-dependent Clp protease ATP-binding subunit VFG0080 Protein 2e-150 50