Gene Information

Name : TBSG_02365 (TBSG_02365)
Accession : YP_005100833.1
Strain : Mycobacterium tuberculosis KZN 4207
Genome accession: NC_016768
Putative virulence/resistance : Unknown
Product : lysyl-tRNA synthetase 2 lysX
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2567344 - 2570868 bp
Length : 3525 bp
Strand : +
Note : -

DNA sequence :
GTGGGAGTGGGACTCCACTTAACTGTCCCTGGCCTTCGCCGGGATGGTCGCGGCGTCCAGTCTAACAGCCATGACACGTC
ATCTAAGACAACGGCCGACATCAGCCGGTGCCCTCAGCACACCGATGCGGGGCTACAAAGGGCTGCAACGCCGGGCATTT
CCCGGCTTTTGGGAATATCCTCGCGGTCTGTGACACTCACCAAACCTCGCTCGGCCACCAGGGGAAACTCCCGGTATCAC
TGGGTTCCCGCGGCAGCCGGCTGGACCGTCGGCGTGATCGCGACCCTGTCACTACTGGCCAGTGTGTCGCCGTTGATTCG
GTGGATCATCAAGGTTCCGCGCGAATTCATCAACGATTATCTGTTCAACTTCCCCGACACCAACTTCGCGTGGTCCTTCG
TGCTGGCATTGCTGGCCGCCGCGTTAACGGCACGCAAACGCATTGCCTGGTTGGTCTTGCTGGCAAATATGGTCCTGGCC
GCCGTGGTCAACGCCGCCGAGATCGCAGCGGGCGGCAACACCGCCGCCGAGAGCTTCGGGGAGAATCTCGGATTCGCCGT
GCATGTTGTGGCAATCGTCGTTCTGGTGCTGGGCTATCGGGAGTTCTGGGCCAAGGTCCGCAGGGGCGCGCTGTTTCGGG
CGGCTGCGGTGTGGCTTGCCGGCGCGGTGGTCGGAATCGTGGCGTCTTGGGGTCTGGTCGAACTGTTTCCGGGATCACTA
GCGCCGGACGAGCGGTTGGGTTACGCGGCCAACCGGGTGGTCGGATTCGCCCTCGCCGATCCCGATCTGTTCACCGGCAG
ACCGCACGTCTTCCTCAACGCGATCTTCGGGTTGTTCGGCGCGTTCGCGTTGATCGGGGCTGCGATCGTCTTGTTCCTAT
CTCAGCGCGCTGACAATGCGCTGACCGGAGAGGACGAATCCGCTATCCGCGGGTTATTGGATTTGTATGGGAAGGACGAC
TCACTGGGCTACTTCGCCACCCGTCGCGACAAGTCGGTGGTATTCGCATCCAGCGGCCGCGCCTGTATCACCTACCGTGT
CGAGGTCGGTGTCTGCCTAGCCAGCGGCGACCCGGTAGGCGACCACAGAGCATGGCCGCAGGCCGTCGACGCGTGGCTGC
GGCTGTGCCAGACCTACGGCTGGGCACCCGGCGTGATGGGCGCCAGTTCACAAGGGGCTCAGACATATCGCGAAGCGGGC
CTAACCGCGCTCGAGCTGGGCGATGAGGCCATCCTGCGGCCAGCCGATTTCAAGTTGTCCGGCCCGGAGATGCGCGGGGT
GCGCCAGGCCGTGACGCGGGCCCGGCGGGCGGGGTTGACGGTGCGCATCCGGCGGCATCGCGACATTGCCGAAGACGAGA
TGGCGCAGACCATCACACGGGCGGATTCCTGGCGCGACACCGAGACCGAGCGCGGCTTCTCGATGGCGCTGGGCCGCCTC
GGCGACCCCGCGGACTCCGACTGCCTGCTGGTGGAGGCGATTGATCCGCACAACCAGGTGCTGGCAATGCTGTCGCTGGT
GCCGTGGGGAACCACCGGTGTCTCCCTGGATTTGATGCGTCGTTCTCCACAATCCCCGAACGGCACTATCGAACTTATGG
TCAGCGAACTCGCCTTGCACGCTGAAAGCCTTGGTATCACTCGTATTTCGTTGAACTTCGCGGTGTTTCGCGCGGCCTTC
GAGCAGGGCGCCCAACTCGGCGCCGGCCCGGTTGCCCGGTTGTGGCGGGGGCTGCTGGTCTTCTTCTCACGGTGGTGGCA
GCTCGAGACGCTCTACCGCTCCAACATGAAGTACCAACCCGAATGGGTACCGCGCTACGCCTGCTACGAAGACGCCCGAG
TGATTCCCCGAGTGGGCGTCGCCTCGGTGATCGCAGAGGGGTTCCTCGTGCTGCCGTTCAGCCGGCGCAACCGAGTACAC
ACGGGGCATCATCCGGCAGTGCCCGAGCGGTTGGCGGCCACCGGCCTATTGCATCACGACGGCTCGGCACCGGACGTGAG
CGGGCTGCGGCAAGTAGGCCTCACCAATGGCGACGGGGTCGAGCGGCGGCTACCCGAGCAGGTGCGAGTTCGGTTCGACA
AGCTAGAGAAGCTGCGGAGCAGCGGCATTGACGCCTTTCCCGTGGGCCGGCCGCCCAGTCACACGGTGGCACAGGCGCTG
GCCGCAGACCACCAGGCTAGCGTGTCGGTGTCCGGACGCATCATGCGAATACGTAACTACGGTGGTGTGTTGTTCGCCCA
GCTGCGCGACTGGTCGGGCGAAATGCAAGTGCTGCTGGATAATTCACGCCTGGACCAGGGCTGCGCGGCCGACTTCAACG
CGGCGACCGATCTGGGTGATCTGGTGGAGATGACCGGACACATGGGCGCCAGCAAGACCGGAACTCCATCGTTGATCGTC
AGCGGCTGGCGCCTGATCGGTAAGTGTTTGCGACCGTTGCCGAATAAGTGGAAGGGGCTACTGGATCCCGAAGCCCGAGT
CCGGACCCGTTACCTCGACCTGGCGGTCAACGCTGAGTCCCGTGCGCTGATCACCGCTCGCAGCAGCGTGCTGCGCGCTG
TGCGCGAGACGCTGTTCGCAAAGGGATTCGTCGAGGTCGAAACGCCGATCCTACAGCAGCTGCACGGCGGCGCCACCGCC
CGACCGTTCGTCACGCACATCAACACGTATTCCATGGATCTGTTCCTGCGCATCGCACCAGAGCTCTACCTCAAGCGCCT
GTGCGTCGGCGGCGTGGAACGGGTATTCGAGCTCGGCCGTGCCTTTCGCAACGAGGGCGTCGACTTCAGCCACAACCCGG
AGTTCACCCTACTGGAGGCCTATCAAGCACACGCCGACTACCTTGAGTGGATTGACGGCTGCCGCGAACTCATCCAGAAC
GCCGCCCAGGCCGCCAACGGGGCGCCCATCGCCATGCGGCCCCGGACGGACAAGGGTTCCGACGGCACCCGCCACCACCT
CGAACCGGTCGACATCTCCGGGATATGGCCGGTGCGGACGGTGCATGATGCGATCTCGGAAGCACTCGGTGAACGCATCG
ACGCCGATACCGGCTTGACCACTCTCCGCAAGCTGTGCGACGCCGCCGGTGTCCCCTATCGGACCCAATGGGATGCCGGC
GCGGTCGTGCTCGAGCTATACGAGCACCTGGTGGAGTGCCGCACCGAGCAACCGACGTTCTACATCGACTTTCCGACATC
GGTGTCACCGTTGACCCGACCGCATCGCAGCAAGCGCGGTGTCGCCGAGCGTTGGGACCTGGTGGCGTGGGGTATCGAGC
TGGGCACCGCCTACAGCGAGCTGACCGACCCGGTGGAGCAACGGCGCCGCCTGCAGGAGCAGTCCCTGCTGGCCGCCGGC
GGAGACCCCGAGGCGATGGAACTCGACGAAGACTTCCTGCAAGCGATGGAGTACGCCATGCCGCCCACCGGCGGCTTGGG
CATGGGCATTGACCGGGTGGTCATGCTGATCACTGGGCGCAGCATTCGCGAAACACTGCCCTTTCCGTTGGCAAAACCGC
ATTAG

Protein sequence :
MGVGLHLTVPGLRRDGRGVQSNSHDTSSKTTADISRCPQHTDAGLQRAATPGISRLLGISSRSVTLTKPRSATRGNSRYH
WVPAAAGWTVGVIATLSLLASVSPLIRWIIKVPREFINDYLFNFPDTNFAWSFVLALLAAALTARKRIAWLVLLANMVLA
AVVNAAEIAAGGNTAAESFGENLGFAVHVVAIVVLVLGYREFWAKVRRGALFRAAAVWLAGAVVGIVASWGLVELFPGSL
APDERLGYAANRVVGFALADPDLFTGRPHVFLNAIFGLFGAFALIGAAIVLFLSQRADNALTGEDESAIRGLLDLYGKDD
SLGYFATRRDKSVVFASSGRACITYRVEVGVCLASGDPVGDHRAWPQAVDAWLRLCQTYGWAPGVMGASSQGAQTYREAG
LTALELGDEAILRPADFKLSGPEMRGVRQAVTRARRAGLTVRIRRHRDIAEDEMAQTITRADSWRDTETERGFSMALGRL
GDPADSDCLLVEAIDPHNQVLAMLSLVPWGTTGVSLDLMRRSPQSPNGTIELMVSELALHAESLGITRISLNFAVFRAAF
EQGAQLGAGPVARLWRGLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYEDARVIPRVGVASVIAEGFLVLPFSRRNRVH
TGHHPAVPERLAATGLLHHDGSAPDVSGLRQVGLTNGDGVERRLPEQVRVRFDKLEKLRSSGIDAFPVGRPPSHTVAQAL
AADHQASVSVSGRIMRIRNYGGVLFAQLRDWSGEMQVLLDNSRLDQGCAADFNAATDLGDLVEMTGHMGASKTGTPSLIV
SGWRLIGKCLRPLPNKWKGLLDPEARVRTRYLDLAVNAESRALITARSSVLRAVRETLFAKGFVEVETPILQQLHGGATA
RPFVTHINTYSMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYLEWIDGCRELIQN
AAQAANGAPIAMRPRTDKGSDGTRHHLEPVDISGIWPVRTVHDAISEALGERIDADTGLTTLRKLCDAAGVPYRTQWDAG
AVVLELYEHLVECRTEQPTFYIDFPTSVSPLTRPHRSKRGVAERWDLVAWGIELGTAYSELTDPVEQRRRLQEQSLLAAG
GDPEAMELDEDFLQAMEYAMPPTGGLGMGIDRVVMLITGRSIRETLPFPLAKPH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysX YP_003784331.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 1e-155 43
lysS1 YP_005686365.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 1e-155 43
lysS1 YP_005682181.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 3e-155 43
lysS1 YP_005684273.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 1e-155 43