Gene Information

Name : copB (SMA_0270)
Accession : YP_005093984.1
Strain : Streptococcus macedonicus ACA-DC 198
Genome accession: NC_016749
Putative virulence/resistance : Resistance
Product : lead, cadmium, zinc and mercury transporting ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 273719 - 275830 bp
Length : 2112 bp
Strand : +
Note : -

DNA sequence :
ATGAGGAATAACAAAAAACATTCGTCACATAGTCATCATAATCACGGTGACATGGATCACTCAAAACACGACCATAATGA
AATGGAACATAGTCAGATGGATCACAGCAAGATGAATCATAGTGCGATGGATCACAGTGAAATGGATCATGGCGCAATGG
GAGGGCATGCCCACCACCATCACGGAAGCTTTAAGGAACTTTTCTTAAAGTCATTGCCACTAGGAATCATTATTATGCTC
TTAGTCCCTTTGCATGGATTTGAACTACCATTCCAGTTTACTTTTCCATATTCTGATATTGTAGTAGCTATTTTATCTAC
TATATTAATTATTTATGGTGGACGTCCATTCTATCAAGGTGCAGTTGACGAATTTAAACAAAAAAAACCTGGAATGATGG
CACTCGTTTCTTTAGGTATAAGTGTTTCATATTTATACAGTATTTATGCTGTGATCATTACCTACGTAACGGGTGAACAC
GTGATGGACTATTTCTTTGAATTTGCTTCATTACTATTAATCATGTTATTAGGTCACTGGATTGAGATGAAAGCTATTGG
AGAAGCAGGAGACGCACAAGCAGAATTGGCTAAGTTAGTGCCGAAAGATGCTCACGTTGTATTAGAAGACGATTCAATTG
AAACACGACCAGTTGCTGACTTAAAGGTAGGTGATTTAATTCGTGTTCAAGCCGGAGAAAATGTGCCAGCAGACGGGATT
ATCGAGCGTGGCGAATCACGTTTAAATGAAGCTCTTTTGACTGGAGAATCAAAAGCAGTTAAAAAAGGCCCTGGCGATGA
AGTAATCGGGGGCTCAACAAATGGAGAAGGGGTTCTTTATATTAAAGTGAATGAGACAGGTGATCAATCCTTCATCTCTC
AAGTTCAGAATTTAATCAGCCAAGCTCAAAGTCAGCCTTCCAGAGCAGAAAATATTGCTCAAAAAGTTGCAGGGTGGCTC
TTCTATATTGCTGTTATTGTCGCGCTAATTGCCTTTGTAGTGTGGATGGTTATAGAAGATATACCAACGGCAGTTATATT
TACTATTACTACATTAGTTATTGCTTGTCCGCACGCATTGGGTTTGGCTATTCCATTGGTAACCGCCCGTAGCACGAGCT
TAGGAGCTAGCCGTGGCTTACTAGTAAAAGACCGCCAAGCCTTAGAAATAGCTCAAGATGCAGATGTGATGATTTTAGAT
AAAACGGGTACTTTAACAACTGGTGAATTTAAAGTATTAGATGTAAAACTTCTTAATGACAAATATACAAAAGAGGAAAT
CATTGCCTTATTGGCAGGTATTGAAGGAGGATCTAGCCACCCAATTGCTCAATCAATTATAAGTTTCGCCGAGCAGCAAA
ATATACGTCCAGCATCTTTTGATTCGATTGATGTGATTTCCGGTGCTGGAGTAGAGGGCGAAGCAGGTGGGCACCGTTAC
CAACTAATCAGTCAAAAAGCCTATGGACGTAATCTTGATATGGATATTCCAAAGGGAGCAACTCTTAGTGTCTTAGTAGA
AAACGATGATGCCATTGGTGCTGTAGCTTTAGGGGACGAATTAAAACCAAAGAGTAAAGAGTTAATTAAAGCTCTTAAAA
AGAACAATATTCAACCAATTATGGCAACAGGTGATAATGAAAAAGCAGCTCAAGGCGCGGCAGTAGATTTAGGGATTGAA
TATAGATCAAATCAATCTCCACAAGACAAATATGAGTTAGTTAAAACACTTAAAGATGAAGGAAAGAAAGTTATCATGGT
AGGTGATGGTGTAAATGATGCTCCTTCTCTTGCCTTAGCAGATGTTGGTATAGCTATAGGTGCTGGAACTCAAGTTGCAT
TGGATTCAGCTGATGTCATATTGACTCAATCCGATCCAGGAGATATTGAATCATTCATTGAATTAGCACACAAAACAACT
CGTAAGATGAAACAAAACCTATTTTGGGGAGCTGGTTATAACTTTATAGCTATCCCTCTAGCTGCAGGAATTTTGGCTCC
TATTGGTATCACATTAAGCCCTGCATTAGGAGCAATCCTAATGTCTGTGTCAACAGTCATCGTCGCCATTAATGCTATGT
TATTAAGTTTAGATCCAAAAAATAACGGTTAA

Protein sequence :
MRNNKKHSSHSHHNHGDMDHSKHDHNEMEHSQMDHSKMNHSAMDHSEMDHGAMGGHAHHHHGSFKELFLKSLPLGIIIML
LVPLHGFELPFQFTFPYSDIVVAILSTILIIYGGRPFYQGAVDEFKQKKPGMMALVSLGISVSYLYSIYAVIITYVTGEH
VMDYFFEFASLLLIMLLGHWIEMKAIGEAGDAQAELAKLVPKDAHVVLEDDSIETRPVADLKVGDLIRVQAGENVPADGI
IERGESRLNEALLTGESKAVKKGPGDEVIGGSTNGEGVLYIKVNETGDQSFISQVQNLISQAQSQPSRAENIAQKVAGWL
FYIAVIVALIAFVVWMVIEDIPTAVIFTITTLVIACPHALGLAIPLVTARSTSLGASRGLLVKDRQALEIAQDADVMILD
KTGTLTTGEFKVLDVKLLNDKYTKEEIIALLAGIEGGSSHPIAQSIISFAEQQNIRPASFDSIDVISGAGVEGEAGGHRY
QLISQKAYGRNLDMDIPKGATLSVLVENDDAIGAVALGDELKPKSKELIKALKKNNIQPIMATGDNEKAAQGAAVDLGIE
YRSNQSPQDKYELVKTLKDEGKKVIMVGDGVNDAPSLALADVGIAIGAGTQVALDSADVILTQSDPGDIESFIELAHKTT
RKMKQNLFWGAGYNFIAIPLAAGILAPIGITLSPALGAILMSVSTVIVAINAMLLSLDPKNNG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SH0105 YP_252020.1 hypothetical protein Not tested SCCmec Protein 2e-95 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
copB YP_005093984.1 lead, cadmium, zinc and mercury transporting ATPase BAC0383 Protein 0.0 83
copB YP_005093984.1 lead, cadmium, zinc and mercury transporting ATPase BAC0079 Protein 3e-138 49
copB YP_005093984.1 lead, cadmium, zinc and mercury transporting ATPase BAC0629 Protein 4e-103 45