Gene Information

Name : clpA (SMA_2088)
Accession : YP_005095647.1
Strain : Streptococcus macedonicus ACA-DC 198
Genome accession: NC_016749
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2029217 - 2031658 bp
Length : 2442 bp
Strand : -
Note : -

DNA sequence :
ATGAGTGAGTATTCGATAAAAATGCAAGAGGTTTTCAGTGTTGCTCAATACCAAGCAGCGCGTTTTGAAAGCCCATATTT
AGAAAGTTGGCACGTCCTTTTAGCTATGGTTGCTATCCATGACTCAGTCGCAGGGCTAACATTTGCGGAATACCAAACTA
AAATTGCTTATGAAGAATATGAAGCGGCAGCTGTTTTAGCCATTGGGAAATCACCGTTAACGGATGTTGACAGAGTTCAC
TTTGTGGAACAATCTAAAGCTCTTAGTGATGTTTTAGCATTTGCTGAGTCTATTTGTCAGGTGACTGGTGGTAACGAAAT
CGGGACAGAACACGTGCTTTATGCGATGTTGTTAAACCTTGATTTATTTGCCACACGTTTGTTAGAGGTTGCTGGTTTTA
AAAACAAAGAAGACGGTGACGCTGCTCGTTTGATTGATTTGCGTAAGAGTTTGGCACGTAATGCTGGTTTTACAAAGGAA
AATATCAAAGCTATTCATGAACTTCGTAAGCCGAAAAAATCGACAATGGGCGGTGCTTTTTCTGAAATGCTGAAACCACA
GTCAACAGCGGAGGATTTGTCAGATTTCACGCGTGATTTGACAGAGATGGCACGTCAAGGAAAATTAGAACCTGTTATTG
GTCGTGAAAAAGAAATTTCTCGTATGGTGCAGGTGCTTAGCCGCAAAACGAAAAACAATCCAGTTTTAGTAGGGGAAGCT
GGTGTTGGTAAAACGGCTCTTGCTTACGGTTTGGCACAGCGAATTGTCAATGGTGCGATTCCGTATGAACTCCAAGACAT
GCGTGTTTTAGAGCTTGATATGATGAGCGTTGTGGCTGGTACGCGATTCCGTGGTGATTTTGAAGAACGCATGAACCAAA
TCATCTCAGATATTGAGGAAGACGGTCATATTATTCTATTCATTGACGAAGTGCATACGATTATGGGTTCAGGCTCTGGA
ATTGACAGCACTTTGGATGCGGCTAATATTTTAAAACCAGCACTTGCGCGTGGTACGCTTCATATGGTTGGTGCGACAAC
GCAAGAAGAATATCAAAAACATCTCGAAAAAGATGCGGCGCTTTCTCGCCGTTTTGCTAAGATTACCATTGAAGAACCAA
GTGTTGAAGATGCTTACCAAATCTTGCTTGGACTAAAGAAATCATATGAAGATTTTCATAATGTGGTGATTTCTGATGAA
GCTGTTTTAACGGCTGTCAAAGCTGCGCATCGCTATTTGACAAGTAAAAATCTTCCTGATTCAGCGATTGATTTGCTTGA
TGAAGCAAGTGCAACGGTTCAAGGTTTGGTGAAAAAAGAAGCGCCAGCTACTTTGACACCTGCTGATAAAGCTATTTTGG
AAGGTGATTTCAAATTGGCAACGAAATTGCTGAAAGAGTCACGCAAGAAGCCAAATCGTAAACCAACTGCTGTGACAGAA
GATGATATTATGGCAACGCTCAGTCGTTTGTCAGGTATTCCTGTTGAGAAAATGACACAGGCAGATAGTAAGAAATACTT
GAACCTCGAAAAAGAATTCCATAAGCGTGTGATTGGCCAAGATTCAGCTATTTCAGCGATTAGTCGTGCTATTCGTCGTA
ATCAAGCGGGCATTCGTACAGGCAAACGTCCGATTGGCTCGTTTATGTTCTTGGGTCCAACGGGTGTTGGTAAAACAGAG
TTGGCTAAGGCACTAGCAGAATTGCTATTTGATGATGAATCTGCTCTTATCCGTTTTGATATGTCTGAGTACATGGAAAA
ATTTGCGGCGAGCCGTCTTAACGGAGCTCCTCCAGGGTATGTCGGTTATGAAGAAGGTGGCGAATTGACTGAAAAAGTTC
GCAACAAACCTTATTCTGTGCTTCTATTTGATGAAATTGAAAAAGCCCACCCAGATATTTTCAATGTGCTTCTCCAAGTG
TTGGATGACGGTGTGCTGACGGATAGTCGTGGTCGTAAAGTTGATTTTTCAAACACGATTATTATCATGACATCAAATCT
TGGGGCAACCGCTTTGCGTGATGAAAAGACAGTTGGTTTTGGTGCGCGTGATATGGCTCATGATTATGAGGCAATGCAAA
AACGCATCATGGAAGAACTCAAAAAAACTTACCGACCTGAATTCATCAACCGTATTGATGAAAAAGTTGTTTTCCACAAC
TTAACTCAAGAAAATATGCGTGATGTCGTGAAAATCATGGTTAAACCATTGATTGCGACACTAGCTGAAAAAGATATTAC
GCTAAAATTCCAACCATCAGCATTGAAATATTTAGCCGAAATTGGATACGACCCAGAAATGGGAGCTCGTCCGCTCCGCC
GTACTCTGCAAGATAAAGTTGAAGATGAATTATCAGAGCTTATTCTATCAGGCGAATTGGCAAGTGGAAATACCCTTAAA
ATCGGTGTTTCTAAAGGGCAACTCAAATTTGATATTGCTTAA

Protein sequence :
MSEYSIKMQEVFSVAQYQAARFESPYLESWHVLLAMVAIHDSVAGLTFAEYQTKIAYEEYEAAAVLAIGKSPLTDVDRVH
FVEQSKALSDVLAFAESICQVTGGNEIGTEHVLYAMLLNLDLFATRLLEVAGFKNKEDGDAARLIDLRKSLARNAGFTKE
NIKAIHELRKPKKSTMGGAFSEMLKPQSTAEDLSDFTRDLTEMARQGKLEPVIGREKEISRMVQVLSRKTKNNPVLVGEA
GVGKTALAYGLAQRIVNGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIISDIEEDGHIILFIDEVHTIMGSGSG
IDSTLDAANILKPALARGTLHMVGATTQEEYQKHLEKDAALSRRFAKITIEEPSVEDAYQILLGLKKSYEDFHNVVISDE
AVLTAVKAAHRYLTSKNLPDSAIDLLDEASATVQGLVKKEAPATLTPADKAILEGDFKLATKLLKESRKKPNRKPTAVTE
DDIMATLSRLSGIPVEKMTQADSKKYLNLEKEFHKRVIGQDSAISAISRAIRRNQAGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEIEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDEKTVGFGARDMAHDYEAMQKRIMEELKKTYRPEFINRIDEKVVFHN
LTQENMRDVVKIMVKPLIATLAEKDITLKFQPSALKYLAEIGYDPEMGARPLRRTLQDKVEDELSELILSGELASGNTLK
IGVSKGQLKFDIA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 1e-134 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpA YP_005095647.1 ATP-dependent Clp protease ATP-binding subunit ClpA VFG0080 Protein 7e-118 47
clpA YP_005095647.1 ATP-dependent Clp protease ATP-binding subunit ClpA VFG0079 Protein 2e-148 45