Gene Information

Name : GU3_14280 (GU3_14280)
Accession : YP_005093359.1
Strain : Oceanimonas sp. GK1
Genome accession: NC_016745
Putative virulence/resistance : Resistance
Product : acriflavin resistance protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3102218 - 3105262 bp
Length : 3045 bp
Strand : -
Note : COG0841 Cation/multidrug efflux pump

DNA sequence :
ATGAATATTGCCGAACATACCCTGGCCAGGCGCACCATTGCCTGGATGACCTGCCTGCTGTTGCTGGTGGGCGGTTACAT
CAGTTATCAGAGCCTGGGCCGGTTTGAAGATCCGGAGTTTGTGATCCGTCAGGCGGTGATCTCCACTCCTTACCCCGGCG
CGCTGCCGGCGCAGGTGGCGGAAGAGGTCACCGAAGTCATTGAAGAGGCCGTGCAGCAATTGCAGGAGCTGAAAGAAGTG
ACCTCGGTATCGCGCATGGGTGACTCGCTGGTGAAGGTGGAAATCGACATGCGCTTTGCCCACAGCGCCCGGGAGCTGGA
GCAGGTGTGGGACAAGCTCCGGCGCAAGGTGAACGACGCCCAGCGTCAGCTGCCGCCGGGGGCGGGGCCGTCGGTAGTGA
ACGACGACTTTGGCGATGTGTATGCGCTGTTTTTTGCGGTCATCGGCGAAGGCTTTACCCTGCAGCAAATCAAGGACTAT
CTGCACGGGCTGGAGCGGGAACTGCTGCAGGTGCCGGGCGTGGCCCGGGTCACGACCCTGGGGGCCCCTCAGGAAGCCAT
TTATCTGGAAATTTCTGCCGCCCAGGCGGCCCGCCTGGACGTGCCTCTGGGCAACATCTACCAGACCCTGCGTCAGCAAA
ACGTGATAAGCGATGCGGGCAACCTGCGGATCGGCCCTCAGCGGGTCTATTTCAGCCCCGAAGGCCAGGCCGACTCGGTG
GCGGCCCTGGGCAATCTGGCCATTACTTCTCAGGATGGCGATCGAGTGGTGTTCCTTAAAGATTTGGCCACCATTACCCG
GGCCGAGAGCGAACCGCCCCGGGCGCTGATGAAGTATGACGGCCAGCCGGCCATTGGCCTGGGCATTTCCCAGGTGGCTG
GCGGCAACGTGGTGAACATGGGCGATGCGGTGCGGGCCCGGCTGGCAGAGCTGGACGGCGAACGCCCCATTGGCATGGTG
CTGAACGAAGTGTCCTATCAGTCCGACTCGGTGCGCGAGGCGGTGGACGGCTTTGTGGCCAACCTGGCGGCGGCGGTGGC
CATAGTGGTGCTGGTACTGGTGCTGTTTATGGGCCTGCGCAGCGGCATCATTGTGGGGGCCGTGCTGCTGCTCACCGTGG
CCGGCACGCTAATCGCCATGAAGCTCGACGGTATTGCCATGCAGCGGGTGTCACTCGGGGCGCTGATCATTGCCCTGGGA
ATGCTGGTGGATAACGCCATTGTGGTGACCGACGGCATTCTGGTGCGCATGCAAAGGGGCGAGCGGGCCGACAACGCCGC
TGCCGCCGTGGTGCAGGCGACCCAGTGGCCGCTTTTGGGCGGTACCGCCGTGGGCATTCTGGCGTTCAGCGCCATTGGTC
TGTCGCCGACCGACATGGGGGAATACGCCGGCTCGCTGTTCTGGGTCATTCTTTACTCCATGCTGCTGAGCTGGCTGTTT
GCGGTGACCCTCACGCCGCTGTTGTGTGTGACCTTGCTGAAAGTGTCACCGGCAGCGGCCAATGCTCCCGAATCGCGTGT
GCTGGCCCGTTATCGCGGAATATTGCGCAGCGCGCTGCAGCACAGGGCCATCACCGGCGGCCTGCTGCTGGCGCTGCTGG
CCGGGGCCATTTTTGGCTTTAACTGGGTGCAGCCTGGCTTTATGCCCGAGTCGGCCCGGCCCCAGTTTGTGGTGGACATG
TATCTGCCTCAGGGTACGGACATTCGGGAAACCGAAGCGGAGCTGTCGCGCATGGGCGACTTTGTGCAACAGCAGGAAGG
GGTCACCCATGTGACCAGCTTTATCGGTCAGGGGGGCTTGCGCTTTATGCTCACCTACGGCCCTGAAGATCCCAACACCA
GTTATGGCCAGCTGCTGGTGGATGTGGAGGATCCCGGCCACATTGCCGACATGGTGGAAGAGCTGCAGCGGCAGCTGTCC
GAGCGGCATCCGCTGGCCGACATCAAGGTATGGAAATTCATGCTGGGCCGGGGCGGCGGCAAGAAAATAGAAGCCGCCTT
TATGGGGCCGGAGCCGGCGGTGCTGCGCCGGCTGGCGGAAGAGGCCAAGGCCATCATAGCGAAGGACGACGGTGCCATTG
CCATTCAGGACGACTGGCGTGAAAAAGTGCCGGTGCTGCGCCCGGTGGTGGATGAAGTGGCCGCCCGCCGGGCCGGACTG
ACCCTGGCCGACATCAGCCAGGCCATTAACCGTGCCTTTAGTGGTGAGCAGATTGGCGTGTACCGGGAAGAGGATCAGCT
TATCCCTATCATTTCCCGGGCACCGGCAGCCGAGCGCACCAGCGCCGACATGGTGGAGAACGTGCAGGTCTACAGTCCCA
CCGCCAGGCAATATGTGCCGGTGAGTCAGCTGGTCACATCGGTGCAGCTGGAATGGGTGGATGCCATTATTCGCCGAGTG
GACAGGTTCCCCACCATTAAGGCCCAGGCGGATCCGCTGCCCGGTGAGCTTTCCGGGCCGCTGCTGGAACGGCTGCGCCC
CGAGATTGAAGCCATGACGCTGCCGCCCGGTTATCGGCTGGAATGGCACGGAGAAGATAAAGCCTCCAAAGAAGCCAATG
AAGGGCTTGCCCTGTCGGCCCCCTATGGTTTCAGCGCCATGATACTGGCGGTGGTGGTGATGTTTAACGCCCTGCGCCAG
CCGCTGGTGATCTGGCTGACTGCGCCCCTGGCCATTATTGGCGTGACCCTGGGGCTGGTGTTATTCCAGGTGCCATTTGA
GTTTATGGCGATTCTCGGCCTGCTCAGTCTGATTGGCATGCTGGTAAAAAACGCCATTGTGCTGGTGGATCAGGCCGATG
TCGAGAGAGCCGACGGCAAGCCGGGTTTTGCCGCCGTGGTGGATGCCGCCGTCAGCCGGGCCCGGCCGGTATTTCTGGGG
GCCTTTACCACCATACTGGGGGTAGCGCCGCTGCTGATGGATCCCTTCTTCAAGAGCATGGCGGTCACCATCATGTTTGG
TCTGGCCTTTGCCACCGTGCTGACCTTGATTGTGGTGCCGCTGCTTTATGTGGCTATCTTTCGCATCAGGCCCGTCGGAT
CATGA

Protein sequence :
MNIAEHTLARRTIAWMTCLLLLVGGYISYQSLGRFEDPEFVIRQAVISTPYPGALPAQVAEEVTEVIEEAVQQLQELKEV
TSVSRMGDSLVKVEIDMRFAHSARELEQVWDKLRRKVNDAQRQLPPGAGPSVVNDDFGDVYALFFAVIGEGFTLQQIKDY
LHGLERELLQVPGVARVTTLGAPQEAIYLEISAAQAARLDVPLGNIYQTLRQQNVISDAGNLRIGPQRVYFSPEGQADSV
AALGNLAITSQDGDRVVFLKDLATITRAESEPPRALMKYDGQPAIGLGISQVAGGNVVNMGDAVRARLAELDGERPIGMV
LNEVSYQSDSVREAVDGFVANLAAAVAIVVLVLVLFMGLRSGIIVGAVLLLTVAGTLIAMKLDGIAMQRVSLGALIIALG
MLVDNAIVVTDGILVRMQRGERADNAAAAVVQATQWPLLGGTAVGILAFSAIGLSPTDMGEYAGSLFWVILYSMLLSWLF
AVTLTPLLCVTLLKVSPAAANAPESRVLARYRGILRSALQHRAITGGLLLALLAGAIFGFNWVQPGFMPESARPQFVVDM
YLPQGTDIRETEAELSRMGDFVQQQEGVTHVTSFIGQGGLRFMLTYGPEDPNTSYGQLLVDVEDPGHIADMVEELQRQLS
ERHPLADIKVWKFMLGRGGGKKIEAAFMGPEPAVLRRLAEEAKAIIAKDDGAIAIQDDWREKVPVLRPVVDEVAARRAGL
TLADISQAINRAFSGEQIGVYREEDQLIPIISRAPAAERTSADMVENVQVYSPTARQYVPVSQLVTSVQLEWVDAIIRRV
DRFPTIKAQADPLPGELSGPLLERLRPEIEAMTLPPGYRLEWHGEDKASKEANEGLALSAPYGFSAMILAVVVMFNALRQ
PLVIWLTAPLAIIGVTLGLVLFQVPFEFMAILGLLSLIGMLVKNAIVLVDQADVERADGKPGFAAVVDAAVSRARPVFLG
AFTTILGVAPLLMDPFFKSMAVTIMFGLAFATVLTLIVVPLLYVAIFRIRPVGS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 0.0 62

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GU3_14280 YP_005093359.1 acriflavin resistance protein BAC0425 Protein 0.0 62
GU3_14280 YP_005093359.1 acriflavin resistance protein BAC0428 Protein 5e-169 45
GU3_14280 YP_005093359.1 acriflavin resistance protein BAC0519 Protein 8e-170 44
GU3_14280 YP_005093359.1 acriflavin resistance protein BAC0526 Protein 4e-164 42