Gene Information

Name : HPL003_03450 (HPL003_03450)
Accession : YP_005073691.1
Strain : Paenibacillus terrae HPL-003
Genome accession: NC_016641
Putative virulence/resistance : Resistance
Product : arsenical pump membrane protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 712670 - 713959 bp
Length : 1290 bp
Strand : -
Note : COG1055 Na+/H+ antiporter NhaD and related arsenite permeases

DNA sequence : 
TTGGTTTTACTGGCATGCATTATATTCTTAGCGACTTTAGTATTGGTGATCTGGCAGCCCAAAAATCTGTCTATTGGCTG
GTCAGCCTGCGGAGGAGCTATACTTGCCCTGCTGGTGGGTGTCGTCGATTTGCATGACGTTTGGGAAGTTACTCAAATTG
TTTGGAATGCGACCCTGGCTTTTGTGACCATTATTCTGATTTCGTTGGTGCTCGATAAAATCGGCTTCTTCGAATGGGCA
GCACTTCACATAGTATGGGCTGCGCGGGGAAGCGGAGCACGGATGTTTGTTTATGTGACCATTCTGGGTGCCGTTGTTGC
TGCCTTTTTTGCGAATGACGGTGCAGCCTTAATTCTGACACCCATTGTACTCGCGATGGTGCGAGCATTGAAATTTGAGG
AGAAAGTGGTTTTCCCGTTCATCATAGCGAGTGGATTTATTGCAGACACAACCTCGCTTCCGCTTGTGGTCAGCAATTTG
GTGAATATTGTATCAGCCGATTTCTTTGGGATCACGTTTATGGAATATGCGAGTCGCATGATTGTGCCTAATTTATTTTC
CTTAGCGGCTAGTATCGTGGTACTGTATCTCTTTTTCCGCAAAAGGATTCCGAAAGAATTTGATGCTTCACAGTTAATAA
CGCCTGCAGAAGCGATTAAAGACCCAAAAATGTTCCGCATGTCCTGGTTTGTTCTCGCGGTGCTGTTGGTTGGCTACTTT
GTGTGCGAATTTTTTAACATTCCTGTTTCTGTGGTAGCTGGCGTGATTGCCGTATTTTTCTTGCTGATGGCGAGAAGAAG
CACTGTGGTACCGATAAAAGAAGTTCTTAAAGGCGCTCCATGGACCATCGTATTTTTCTCCATCGGGATGTATGTTGTGG
TGTATGGCCTGCGTAATGCAGGTTTGACAGATCTGCTGGCTCATGTGATTCAAGCGGCTGCTGATCAAGGCATGTTTGTG
GCCACCGTTGGTATGGGCTTTATCGCGGCAGTCATCTCGTCAGTGATGAATAACATGCCTACGGTCATGATTAATGCGCT
TGCCATTGATGCCACGCATACCACCGGCATGATCAAAGAGGCGCTGATTTATGCCAATGTGATTGGATCGGATTTGGGGC
CGAAAATAACCCCGATTGGTTCATTGGCGACATTATTATGGCTGCATGTGCTTGGCTCTAAAGGCGTGAAAATTTCTTGG
GGAGCTTATTTTAAAACAGGCATTATTTTAACGATTCCTACACTTTTTATTACTCTTTTAGGCCTGTATCTGTGGCTGGT
CATTTCATAA

Protein sequence : 
MVLLACIIFLATLVLVIWQPKNLSIGWSACGGAILALLVGVVDLHDVWEVTQIVWNATLAFVTIILISLVLDKIGFFEWA
ALHIVWAARGSGARMFVYVTILGAVVAAFFANDGAALILTPIVLAMVRALKFEEKVVFPFIIASGFIADTTSLPLVVSNL
VNIVSADFFGITFMEYASRMIVPNLFSLAASIVVLYLFFRKRIPKEFDASQLITPAEAIKDPKMFRMSWFVLAVLLVGYF
VCEFFNIPVSVVAGVIAVFFLLMARRSTVVPIKEVLKGAPWTIVFFSIGMYVVVYGLRNAGLTDLLAHVIQAAADQGMFV
ATVGMGFIAAVISSVMNNMPTVMINALAIDATHTTGMIKEALIYANVIGSDLGPKITPIGSLATLLWLHVLGSKGVKISW
GAYFKTGIILTIPTLFITLLGLYLWLVIS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 7e-126 68
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 8e-129 68
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 2e-131 67
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 1e-106 59

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPL003_03450 YP_005073691.1 arsenical pump membrane protein BAC0574 Protein 2e-128 68
HPL003_03450 YP_005073691.1 arsenical pump membrane protein BAC0575 Protein 8e-132 67
HPL003_03450 YP_005073691.1 arsenical pump membrane protein BAC0578 Protein 3e-106 60
HPL003_03450 YP_005073691.1 arsenical pump membrane protein BAC0576 Protein 4e-106 60
HPL003_03450 YP_005073691.1 arsenical pump membrane protein BAC0577 Protein 4e-104 59
HPL003_03450 YP_005073691.1 arsenical pump membrane protein BAC0031 Protein 2e-102 59