Gene Information

Name : AciX8_0046 (AciX8_0046)
Accession : YP_005055436.1
Strain : Granulicella mallensis MP5ACTX8
Genome accession: NC_016631
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 53003 - 55636 bp
Length : 2634 bp
Strand : -
Note : TIGRFAM: Chaperonin ClpB; PFAM: ATPase, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; Clp ATPase, C-terminal; KEGG: aca:ACP_2407 ATP-dependent chaperone protein ClpB; SMART: ATPase, AAA+ type, core

DNA sequence :
ATGGCTATCAAGTGGGACAAATTTACAGTGAAGTCGCAGGAAGCGATCCAGGGAGCGCAGGGGCATGCCGCCGAAAACGG
CAACCCTGAGGTATTACCGCTGCACCTGATGGCGGCCCTGCTGGAAGACAAAGAAGGAGTGGTGTTGCCGGTGCTCGAGA
AAGTCGGCGTGCCAGCACAGCAGTTGCTCGCGCAGGTGAATGCCGCCATCGACAAGCTGCCGAAGGTGCAGGGAGCGGCG
CAGCCGGGGCTGGGCAGTGCGATGCAGAAGGTTTTGGACGGCGCGTTCAAGGAAGCGGAGAACTTCAAGGACGACTACGT
GTCGACAGAACATCTCCTGCTCGCACTAAGCGCGAGCAAAGGTGAGCCGGTGCAGACCGCGCTGGCTGCGTTTGGCGCGG
ACCATACGGCGATCCTGAAGGCCTTGCAGGCCGTGCGCGGCTCGCAGCGTGTGACCGACCAGAATCCCGAGGGCAAGTTC
CAGGCTCTGGCGAAGTATGCCAAGGACCTCACGGAGCAGGCGCGGCGCGGCAAGCTCGATCCCGTGATCGGGCGCGACGA
GGAGATTCGGCGTGTGATCCAGGTGCTCTCGCGGCGCACGAAGAACAACCCCGTCCTGATCGGCGAACCCGGCGTTGGAA
AGACAGCCATCGTCGAAGGTCTGGCGCGGCGCATCTTCCAGGGCGACGTGCCGGAGATCCTGCGCGACAAGCGCGTGATC
TCGCTCGACCTGGGCTCGATGCTGGCGGGCGCAAAGTTTCGCGGTGAGTTCGAAGACCGCCTGAAGGCTGTGCTCAAGGA
GATCGAGGAGTCGAACGGACAGATCATCCTGTTCATCGACGAGCTGCATACCCTGGTAGGCGCGGGCGCCGCCGAGGGCT
CCATCGACGCGAGCAACATGCTCAAGCCGGCGCTGGCACGCGGCGAGCTGCGCGCCATCGGCGCGACGACGCTGAACGAG
TATCGCAAGTACATCGAGAAGGATGCGGCGCTGGAACGGCGCTTCCAGATCGTCTTCGTCGGAGAACCGAACGTCGAAGA
CACGATTGCGATTCTGCGCGGGCTAAGGGAAAGATACGAAACGCACCACAAGGTGCGGATCAAGGATTCGGCCATCGTAG
CCGCAGCGGAGCTGTCGCATCGCTACATCAGCGACCGGTTCCTGCCGGACAAGGCCATCGACCTCGTCGATGAAGCCGCG
GCAGCGCTGGCAATTCAGATCGGCAGCGTGCCGGTGGAGATCGACGACCTGGAACGGCGGGCGACCTCGCTCGAGATCGA
GCGCGCAGCCCTGCAGCGTGAGGACGACGTGAACTCGAAGGAGCGTCTGCACGACGTCGAGCGCGAGCTCGCCGAGGTGC
AGGAGAAGGCCTCCGGTCTGCGCGCTCGCTGGCAGAAAGAGCGCGGCGCCATCGGTCAGGTGGCGGAGTTGAAGCAGAAG
CTGGAAGCCCTGCGCTTCGAGGCGGAAGACGCCACCCGCAAGGGCAATCTGCAACGCGCGGCGGAGCTGCAGTACGGCGA
GATTCCGAAGCTGGAACGTGAGCTGAAGGAGTTGACCGCCACCCAGGACGCCGGTGTTGCCGACGCCAAGTCGGGCGACA
GCGCCTCGCGCTTGTTGAAAGAAGAGGTTGACGAGGAGGATATCGCGAAGATCGTCTCTAAGTGGACGGGCATTCCTATC
GCGAAGATGCTCGAAGGCGAGGTCCAGAAGCTGACGCAGATGGAGCAGCGTCTGCGCGAGCGTGTGGTCGGCCAGGACGA
GGCACTGGTAGTGGTCGCGAATGCGATTCGCCGCTCCCGTGCGGGTCTCAGCGATCCGAAGCGGCCGATCGGAAGCTTCA
TCTTCCTCGGTCCTACCGGTGTCGGCAAGACCGAGACGGCGCGTGCGCTGGCGGAGTTTCTCTTCGACGACGAGCAGGCG
ATGGTACGCATCGACATGTCGGAGTACATGGAGAAGCACGCCGTAGCACGGCTGATCGGCGCGCCCCCGGGATACGTTGG
CTTCGATGAGGGCGGACAGCTGACCGAGGCCATCCGGCGCAGGCCGTATGCTGTGGTGCTGTTCGACGAGATCGAGAAGG
CGCACCCGGATGTCTTCAACGTGCTGCTGCAGGTGCTCGACGACGGGCGTTTGACCGACTCCAAGGGCCGTACCGTGGAC
TTCAAGAACACGGTGCTGATCATGACCTCGAACCTCGGCGCGGGGCAGCTTTCGACCGCCTGGGCCGAGGGCGAGGACGG
CTTCGCAGAGGCGAAGAACCGCGTGATGGAAGAGCTGCGCAAGCACTTCCGTCCGGAGTTCCTGAACCGCGTGGACGACA
CGGTTGTCTTCCATCCGCTGGGCGAGAGCCAGTTGACGCACATCGTCGACCTGCGGCTGGCGGACCTGCAGAAGATGCTC
GCAGACCGCCGCATTACGCTGACCCTGACGGACGCGGCGCGCACTGCGATCTTCAAGGCAGGTTACGACCGCGCCTATGG
AGCAAGGCCGCTGAAGCGGGCGATCCAGCGCCTGGTACAGGACCCGCTGGCGATGCGGATCCTCGACGGGCGCGTGCTCC
ACGGCGACCGCGTGAAGGTCGAAGCGGACAAGAAGGGCGTGCTGGAGTTCGTGGTGGAGAACCGCGAGGCGTAA

Protein sequence :
MAIKWDKFTVKSQEAIQGAQGHAAENGNPEVLPLHLMAALLEDKEGVVLPVLEKVGVPAQQLLAQVNAAIDKLPKVQGAA
QPGLGSAMQKVLDGAFKEAENFKDDYVSTEHLLLALSASKGEPVQTALAAFGADHTAILKALQAVRGSQRVTDQNPEGKF
QALAKYAKDLTEQARRGKLDPVIGRDEEIRRVIQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIFQGDVPEILRDKRVI
SLDLGSMLAGAKFRGEFEDRLKAVLKEIEESNGQIILFIDELHTLVGAGAAEGSIDASNMLKPALARGELRAIGATTLNE
YRKYIEKDAALERRFQIVFVGEPNVEDTIAILRGLRERYETHHKVRIKDSAIVAAAELSHRYISDRFLPDKAIDLVDEAA
AALAIQIGSVPVEIDDLERRATSLEIERAALQREDDVNSKERLHDVERELAEVQEKASGLRARWQKERGAIGQVAELKQK
LEALRFEAEDATRKGNLQRAAELQYGEIPKLERELKELTATQDAGVADAKSGDSASRLLKEEVDEEDIAKIVSKWTGIPI
AKMLEGEVQKLTQMEQRLRERVVGQDEALVVVANAIRRSRAGLSDPKRPIGSFIFLGPTGVGKTETARALAEFLFDDEQA
MVRIDMSEYMEKHAVARLIGAPPGYVGFDEGGQLTEAIRRRPYAVVLFDEIEKAHPDVFNVLLQVLDDGRLTDSKGRTVD
FKNTVLIMTSNLGAGQLSTAWAEGEDGFAEAKNRVMEELRKHFRPEFLNRVDDTVVFHPLGESQLTHIVDLRLADLQKML
ADRRITLTLTDAARTAIFKAGYDRAYGARPLKRAIQRLVQDPLAMRILDGRVLHGDRVKVEADKKGVLEFVVENREA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 2e-120 45
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 4e-113 43
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 3e-113 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
AciX8_0046 YP_005055436.1 ATP-dependent chaperone ClpB VFG2076 Protein 1e-125 43
AciX8_0046 YP_005055436.1 ATP-dependent chaperone ClpB VFG2084 Protein 9e-117 42