Gene Information

Name : Clocl_0547 (Clocl_0547)
Accession : YP_005045186.1
Strain : Clostridium clariflavum DSM 19732
Genome accession: NC_016627
Putative virulence/resistance : Virulence
Product : chaperone ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 624302 - 626734 bp
Length : 2433 bp
Strand : +
Note : PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA)

DNA sequence :
ATGTATGGACGTTTTACCGAAAAGGCAGAGAGAGCTGTAAACCTCTCACAGGAAAGCGCGATGGCTTTAGGTCATAATTA
TGTTGGAACAGAGCATTTGCTGCTTGGTTTGATAAAAGAAGGAAGCGGAGTTGCTGCAAAGGTTCTTCAAAATCAGGGAA
TAACTGAAGAAAAGGTACTTAAGGAAATAGAGGAGTTAATAGGGCATGGAGAGTATACCGGTGAGCAGCCGTTAGGTTTT
ACTCCAAGAACAAAAAGAGTGCTTGAGCTTAGCTTCAGGGAAGCCAGAAGAATGGGACATAATTATATCGGAACAGAGCA
TCTTTTAATAGGTATACTGAAAGAAGGAGAAAGTGTAGCTGTCAGAATTTTAATGGATTTGGGATTAGAACCGCAAAAAC
TGTATTCTGAAGTTCTGAAGATGTTTACAGAAGAGGCTCCGGGGGCAGCAGGAGTTCCCAAAAACCATTCTGCCAGTTCA
AACACTCCAACTCTTAATCAGTTTGGAAGAGATTTAACTGAGATGGCCAGAGAGGCAAAGTTTGACCCGGTTATAGGAAG
AGATAAAGAAATTGAAAGGGTAATTCAGATTTTGAGCAGGAGAACCAAAAACAATCCTTGCTTAATAGGGGAACCGGGAG
TTGGAAAGACAGCAATAGCTGAAGGATTGGCTCAAAAGATTGTTGAAGGAAATATACCGGAAATATTAAAGGATAAAAGA
GTAGTAACCTTAGACTTGTCCTCCATGGTAGCTGGGGCAAAGTATAGGGGTGAATTTGAGGAAAGGCTGAAAAAGGCTCT
TGAAGAGATAAAGAAAGCAGGAAACGTAATACTTTTCATTGATGAGATGCACACAATCATCGGAGCTGGTGCTGCCGAAG
GTGCCATTGATGCCTCCAATATTTTGAAGCCATCCCTTGCAAGAGGTGAAATACAGGTAATAGGTGCAACCACTCTCGAC
GAATACAGAAAGCATGTTGAAAAAGATGCTGCTTTAGAGAGAAGGTTTCAGCCTATTATAGTGGGAGAACCTACTGTAGA
AGAAGCTATTGAGATATTAAAGGGTATTAGGGATAAATATGAAGCACACCATAGGGTGAAAATAACTGATGAAGCACTTG
TGGCTGCAGTGAAACTTTCGGACAGATATATAACCGATCGCTTCCTGCCGGACAAGGCCATAGATTTGATTGACGAAGCG
GCTTCGAAAGTCAGACTAAGATCTTTTACTGCACCGCCCAATTTAAAACAGTTGGAAGAGCAAGTGGAAAGACTGAGAAA
AGAAAAAGAGGATTCTATAATATGCCAGGAGTTTGAAAAAGCGGCTCGTATAAGGGATGAAGAGCAGCGATTGAAGAATG
AGCTGGAAAAAGCAAAGAATGACTGGCAGCAAAAGAATCAGACCACTACCAATACTGTTACTGAAGAAGAAGTAGCAGGA
ATTGTAGCTGACTGGACCGGAATACCTGTTAAGCGTCTTGCTGAAGAAGAATCAGAAAGACTTATGAAAATGGAAGAAAT
TCTCCATAATAGGGTAATCGGTCAGGAAGAGGCGGTTAAAGCTGTATCCAAAGCTATTAGGAGAGGAAGAGTCGGCCTGA
AAGATCCTAAGAGACCGGTGGGTTCATTTATATTCTTAGGACCGACAGGGGTTGGGAAAACCGAACTTAGCAAGGCTCTT
GCCGAGGCTTTGTTTGGAGATGAAAACGCTATTATCAGAATTGATATGTCCGAGTACATGGAGAAGCACAGTGTATCGCG
TTTGGTGGGATCACCTCCGGGATATGTGGGATATGAAGAAGGAGGACAGCTTACAGAAAAAGTAAGAAGGAAGCCTTATT
CAGTGGTATTGTTCGATGAGATTGAAAAGGCACATCCCGATGTATTTAATTTGCTGCTTCAAATACTGGAAGACGGAAGG
CTTACCGACTCACAGGGAAGAGTTGTTGACTTTAAGAATACTGTAATCATAATGACATCAAACGTTGGGGCAAGGCTTAT
AACCGAGCCTAAAAGACTGGGATTTGCTTCGGCAAATGTTGATAAAGCAAAGAATTATAACGACATGAAAAATAATGTTA
TGGGTGAACTTAAAAATACCTTCAGACCTGAGTTCTTAAACAGAGTGGATGAAATAATAGTGTTCCATCCATTGGAGGAA
GAACATCTGAAACGCATTGTAGGACTTATGATTGACAACCTTGCAAAGAGACTTAAAGAGAATGCAATTGAGTTAGAGGT
AACGGAAGATGCAAAATTACTTTTAGCTAAAAAAGGTTTTGACCAGGTTTATGGAGCAAGACCTTTAAGAAGAGCTATAC
AGAGTATGGTGGAAGACAAATTGGCAGAAGAAATGCTTGAAGGAAGAGTCAAAGCAGGAGATAAAGTGGTAATTGAAAGC
AAGGATGAAGAGTTGGTATTGAATAAAGTATAA

Protein sequence :
MYGRFTEKAERAVNLSQESAMALGHNYVGTEHLLLGLIKEGSGVAAKVLQNQGITEEKVLKEIEELIGHGEYTGEQPLGF
TPRTKRVLELSFREARRMGHNYIGTEHLLIGILKEGESVAVRILMDLGLEPQKLYSEVLKMFTEEAPGAAGVPKNHSASS
NTPTLNQFGRDLTEMAREAKFDPVIGRDKEIERVIQILSRRTKNNPCLIGEPGVGKTAIAEGLAQKIVEGNIPEILKDKR
VVTLDLSSMVAGAKYRGEFEERLKKALEEIKKAGNVILFIDEMHTIIGAGAAEGAIDASNILKPSLARGEIQVIGATTLD
EYRKHVEKDAALERRFQPIIVGEPTVEEAIEILKGIRDKYEAHHRVKITDEALVAAVKLSDRYITDRFLPDKAIDLIDEA
ASKVRLRSFTAPPNLKQLEEQVERLRKEKEDSIICQEFEKAARIRDEEQRLKNELEKAKNDWQQKNQTTTNTVTEEEVAG
IVADWTGIPVKRLAEEESERLMKMEEILHNRVIGQEEAVKAVSKAIRRGRVGLKDPKRPVGSFIFLGPTGVGKTELSKAL
AEALFGDENAIIRIDMSEYMEKHSVSRLVGSPPGYVGYEEGGQLTEKVRRKPYSVVLFDEIEKAHPDVFNLLLQILEDGR
LTDSQGRVVDFKNTVIIMTSNVGARLITEPKRLGFASANVDKAKNYNDMKNNVMGELKNTFRPEFLNRVDEIIVFHPLEE
EHLKRIVGLMIDNLAKRLKENAIELEVTEDAKLLLAKKGFDQVYGARPLRRAIQSMVEDKLAEEMLEGRVKAGDKVVIES
KDEELVLNKV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 58
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 3e-96 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Clocl_0547 YP_005045186.1 chaperone ATPase VFG0079 Protein 0.0 64
Clocl_0547 YP_005045186.1 chaperone ATPase VFG0080 Protein 1e-155 53