Gene Information

Name : Clocl_3625 (Clocl_3625)
Accession : YP_005048018.1
Strain : Clostridium clariflavum DSM 19732
Genome accession: NC_016627
Putative virulence/resistance : Unknown
Product : type I restriction-modification system methyltransferase subunit
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4252348 - 4253850 bp
Length : 1503 bp
Strand : -
Note : PFAM: N-6 DNA Methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM)

DNA sequence :
ATGGCAACGGTGAATTTGGGCTTTGAAAATAATCTATGGGAAATGGCCGATAAACTACGCGGCAACATTGAAGCATCGGA
ATATAAGCATGTGGTACTGGGACTCATTTTCCTTAAATACATCTCCGATGCTTTTGAAGAGAGATATAATGAACTGGTTG
CAGAAGGAGAAGGCTTTGAGGAAGATATAGATGCTTATACTGAGGTGAATGTTTTTTACGTACCGAAAGAGGCCCGTTGG
GATTATATAAAAGCAAATGCAAAACAGCCAACGATTGGACAGATTATTGATGAAGCAATGATAGCGATTGAAAAGGAAAA
CGCCTCTCTTAAAGGAGTGCTTCCTAAAAACTATGCCCGCCCGGAGATAGACAAAACCAAGCTCGGCGAGCTTATTGACC
TGTTTTCCTTCAAAGTTGGCGATAAAGAAGCAAGGGCACAGGATGTTCTTGGCAGGGTTTATGAATATTTCCTTGGTAAG
TTTGGCTCTTCGGAAGGTGAATTCTATACTCCGCCCTCAATTGTAAAATTGCTTGTTGAAATGATAGAACCATATAAAGG
CAGGGTGTATGACCCCTGTTGCGGGTCCGGTGGTATGTTTGTGCAGAGCCAGAGATTTGTTGAAGAGCATAGCGGAAGAA
AGGATGATATCCATATATTTGGGCAGGAGTATACCGCTACCACATGGCGTCTATGCAAGATGAACCTTGCTATTCGAGGA
ATTGACGGAAATCTCGGAGAAAGGGATGCAGATACATTTTCCAATGACCTTCATAAGATGCTGAAGGCGGATTATATACT
TGCAAATCCCCCCTTTAACATCAAGGACTGGGGAGCTAACAGGCTTGTTGATGACGTTCGCTGGAAGTATGGCATGCCAC
CGGCAGGAAATGCTAACTATGCCTGGATACAGCATATAATTTCCAAGCTTTCACCGAACGGGGTAGCAGGCTTTGTCATG
GCCAACGGTGCCATGTCCACCAATACAACAAGTGAAGCCGAAATAAGAAAGAACATTATCGAGGACAAGTTGGTGGACTG
TATCATCACTCTGCCGCCCAATCTTTTCTACAATGTCACCATTCCTGCTTGCCTGTGGTTCCTGACAAGAAACAAAAAAT
CCGATGGCCGGGATCGCAGCAACGAAATCCTTTTTATAGATGCCCGTAAGATGGGGACAATGATTGACCGCAAGCACAGA
GAACTAGACTATGAAACTGAGATAAAATATATAGCCGACACCTACCATAGGTGGAAAAAAGGTGAAGGGTACGAGGATAT
CAAGGGATTTTGCAAATCTGCCACTCTGGATGAAGTTCGCTCCCATGAATATATTCTTACTCCCGGTAGGTATGTGGGGA
TTGAGGAAAAAGCTGATGACGGGGAGCCTTTCGATGAAAAGATGACCAGGCTGACCGGAGAACTTGCAGAGATGTTTGCA
AAGCGTAAGTCTTTGGAAGACGAAATCCGCAAAAGACTGGGGGCAATCGGTTATGACTTTTAA

Protein sequence :
MATVNLGFENNLWEMADKLRGNIEASEYKHVVLGLIFLKYISDAFEERYNELVAEGEGFEEDIDAYTEVNVFYVPKEARW
DYIKANAKQPTIGQIIDEAMIAIEKENASLKGVLPKNYARPEIDKTKLGELIDLFSFKVGDKEARAQDVLGRVYEYFLGK
FGSSEGEFYTPPSIVKLLVEMIEPYKGRVYDPCCGSGGMFVQSQRFVEEHSGRKDDIHIFGQEYTATTWRLCKMNLAIRG
IDGNLGERDADTFSNDLHKMLKADYILANPPFNIKDWGANRLVDDVRWKYGMPPAGNANYAWIQHIISKLSPNGVAGFVM
ANGAMSTNTTSEAEIRKNIIEDKLVDCIITLPPNLFYNVTIPACLWFLTRNKKSDGRDRSNEILFIDARKMGTMIDRKHR
ELDYETEIKYIADTYHRWKKGEGYEDIKGFCKSATLDEVRSHEYILTPGRYVGIEEKADDGEPFDEKMTRLTGELAEMFA
KRKSLEDEIRKRLGAIGYDF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 5e-172 66
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 2e-171 66
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 1e-170 66
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 2e-117 46