Gene Information

Name : ureC (KOX_03095)
Accession : YP_005016599.1
Strain : Klebsiella oxytoca KCTC 1686
Genome accession: NC_016612
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 651428 - 653131 bp
Length : 1704 bp
Strand : +
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAGTGACATTTCACGTCAGGCCTATGCCGACATGTTCGGCCCCACCACCGGCGATAAAGTTCGCCTGGCGGACACCGA
GCTGTGGATCGAGGTCGAAGATGATTTGACCACCTACGGCGAAGAGGTCAAATTCGGCGGTGGCAAAGTGATCCGCGACG
GTATGGGCCAGGGACAGATGCTTTCCGCCGGGTGCGTGGATCTGGTGCTGACCAATGCCCTGATCGTCGATTACTGGGGG
ATCGTCAAAGCCGATATCGGCGTCAAAGACGGGCGGATCTTCGCGATCGGCAAAGCCGGCAACCCGGATATTCAGCCAAA
CGTCACGATCGCGATCGGCGCGGCCACGGAAATTATTGCGGCGGAAGGCAAGATCGTCACCGCCGGCGGCGTCGATACGC
ATATTCACTGGATCTGTCCGCAGCAGGCGGAAGAGGCGCTGGTCTCCGGCGTCACCACCATGATCGGCGGCGGGACCGGC
CCGGCGGCGGGCACCAACGCCACGACCTGCACGCCCGGGCCGTGGTACATCTCGCGGATGCTGCAGGCCGCGGACAGCCT
GCCGGTCAATATTGGCCTGCTGGGTAAAGGCAATGGTTCGAATCCGGATGCGCTGCGTGAGCAGGTCGCGGCCGGGGTTA
TCGGCCTGAAAATTCACGAAGACTGGGGCGCGACCCCGGCGGCAATCGACTGCGCGCTGACGGTGGCCGACGAAATGGAC
GTACAGGTCGCTCTGCACAGCGACACCCTCAATGAGTCCGGATTCGTTGAGGATACCCTGGCGGCCATCGGCGGGCGCAC
TATCCATACTTTCCATACCGAAGGGGCGGGCGGCGGCCATGCGCCGGATATTATTACCGCCTGCGCGCACCCCAATATTC
TGCCCTCGTCGACCAACCCGACGCTGCCCTATACCGTCAACACCATTGACGAACATCTGGATATGCTGATGGTTTGCCAT
CATCTCGACCCGGATATCGCCGAGGACGTGGCGTTTGCCGAATCGCGCATTCGGCGGGAAACCATTGCCGCGGAAGACGT
CCTGCACGATCTGGGCGCCTTCTCCCTCACCTCGTCTGATTCGCAGGCGATGGGCCGCGTCGGCGAAGTGGTGTTGCGCA
CCTGGCAGGTGGCGCACCGGATGAAGGTCCAGCGCGGCCCGCTGGCGGAAGAGAGCGGCGATAACGACAACTTCCGTGTG
AAGCGCTATATCGCCAAATACACCATTAATCCGGCGTTAACCCACGGTATCGCCCATGAAGTCGGTTCGATTGAAGTGGG
GAAACTGGCGGATCTGGTGCTGTGGTCCCCGGCGTTCTTCGGCGTGAAGCCGGCGACGATCGTCAAAGGCGGCATGATCG
CGATGGCGCCGATGGGCGACATCAACGCCTCTATCCCGACGCCGCAGCCGGTGCACTATCGCCCGATGTTCGGCGCGCTG
GGCAGCGCTCGCCACCGCTGCCGTTTGACCTTTCTGTCGCAGGCGGCGGCGGAAAACGGCGTCGCTGAACGGCTGAACCT
GCACAGCGCGACGGCGGTGGTTAAAGGCTGCCGCACGGTACAAAAAGGCGATATGCACCACAACGGCCTGCTGCCCACTA
TTACCGTGGATTCGCAAACCTACGAGGTGCGCATCGACGGCGAACTGATAACCAGCGAACCGGCGGACGTGTTACCGATG
GCGCAACGTTATTTCCTGTTTTAA

Protein sequence :
MSDISRQAYADMFGPTTGDKVRLADTELWIEVEDDLTTYGEEVKFGGGKVIRDGMGQGQMLSAGCVDLVLTNALIVDYWG
IVKADIGVKDGRIFAIGKAGNPDIQPNVTIAIGAATEIIAAEGKIVTAGGVDTHIHWICPQQAEEALVSGVTTMIGGGTG
PAAGTNATTCTPGPWYISRMLQAADSLPVNIGLLGKGNGSNPDALREQVAAGVIGLKIHEDWGATPAAIDCALTVADEMD
VQVALHSDTLNESGFVEDTLAAIGGRTIHTFHTEGAGGGHAPDIITACAHPNILPSSTNPTLPYTVNTIDEHLDMLMVCH
HLDPDIAEDVAFAESRIRRETIAAEDVLHDLGAFSLTSSDSQAMGRVGEVVLRTWQVAHRMKVQRGPLAEESGDNDNFRV
KRYIAKYTINPALTHGIAHEVGSIEVGKLADLVLWSPAFFGVKPATIVKGGMIAMAPMGDINASIPTPQPVHYRPMFGAL
GSARHRCRLTFLSQAAAENGVAERLNLHSATAVVKGCRTVQKGDMHHNGLLPTITVDSQTYEVRIDGELITSEPADVLPM
AQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 0.0 95
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 0.0 95
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-162 64
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-162 64
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 2e-162 64
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-162 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_005016599.1 urease subunit alpha VFG0270 Protein 1e-151 63