Gene Information

Name : KOX_22805 (KOX_22805)
Accession : YP_005020518.1
Strain : Klebsiella oxytoca KCTC 1686
Genome accession: NC_016612
Putative virulence/resistance : Virulence
Product : outer membrane usher protein LpfC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4909955 - 4912492 bp
Length : 2538 bp
Strand : -
Note : COG3188 P pilus assembly protein, porin PapC

DNA sequence :
ATGACAATAAAAAATAATAAGTTGCGACCTGCTCGTCTGGCTACGCTTATCGCCATAGCGTTAACCGGTTTCTCTCCGGA
ACTGTATGCCAGTGATTCGTTTAATACGGCCCTGGTAGAGTTAGATAATCCCGGCGTGGGCAAAGCGGATTTATCGGCTT
TTGAATCGGGCTCTCAGGCGCCGGGAACATACCATGTGGATATTATTCTTGATGACCAGTTAATGGACACCCGGGATATT
CCTTTTTCGATGGCAAAAAACGGGGGTGGTAATGAGGTATTACAGCCCTGTCTGAGCGTGGAACAATTAAAACAGTGGGG
AGTGAAAACCGAACTTTTTCCCCAGCTGTCGGTAGAAAATAGTGATTGCGCCAATCTCCAGGCTATTCCGCAAGCCAGCG
CTGATTTTCAGTTTGGCGCCCAGCGGCTGGTTATCAGTATTCCCCAGGCGGCGATCGACCTGCCGGCCAGGGGCTATGTA
CCGCCGGAAATGTGGGATGAGGGGATTACTGCGGCATTGCTCAATTACAGCCTGAGCGGAGCGAACACTCGGGCGAAAAC
GGGCCAGGGCGGCAGAAGCGACAGCCAGTATGCGAACCTGCGTCCGGGGATCAATATCGGACCCTGGCGTTTTCGCAACT
ATACCACCTGGTCACGGGAGTCCTCCGGCCAGGATAAATGGGATACCGTTTATACCTATGCGCAGCGGGCCATTATTCCT
CTGAAAGCCCAGCTTACCGTTGGCGACAGCTCTGCGCCTGCCGACGTGTTCGACAGTATGCCGTTTCGCGGCGGCCAGTT
GGCATCCGATGACGACATGCTGCCGGATTCTCTTAAGGGCTATGCGCCCGTAGTACGCGGCATTGCCCGAACCAATGCGC
AGGTCGTGGTGCGCCAGAACGGCTACCAGATCTACCAAAGCTACGTTGCGCCGGGCGCCTTTGAAATCACGGATATGTAT
CCTACCGGTGGGGCAGGCGATCTCGACGTGACGATTAAAGAAGCCGATGGCAGCGAACAGCACTTCACGCTGCCCTACGC
CTCGCTGCCTGTACTGCAGCGGGAAGCCCGGTTCAAATACGCCATCACCGGCGGGCAGTATCGTTCATATAACAGCAGCG
TGGATAAAACCCCTTTCGGGCAGACAACGGCAATTTATGGCCTGCAGCATGGCTTTACCCTCTATGGCGGCCTGCAGGAG
TCAAGCAAATATCAGTCGCTGGCATTCGGCGTGGGTAAAAATATGGGGGCGTTAGGCGCTATCTCCACGGATGTCACGCA
GGCCTGGTCAACGCCGGATAAAACGGATAAATCGCGCGGCCAATCCTGGCGAGCGCGATACAGCAAAAACTTCATCGATA
CCGGGACCAACTTTTCCATTGCGGGATACCGCTATTCCACCAGCGGCTATTACGGGATGCAGGAAGTTCTGGATTCATAT
GGAGACAGCAGCGCGCTGCAGGACCGCAGGCGTAACCGCGCGGAGCTGACGATGAGCCAGACGCTGAGCCGCGAACTGGG
ATCGCTAACCCTCAGCGCGGCGAGGGAAGATTACTGGAACTCCGCCAGGTCGATGGCTTCCTGGAGCGTCGGATACAACA
ACTACTGGCGCAATATCAGCTACGGCCTGACCTGGACATACAGCAAAAATGGTAGCGCGACGTCAAACGACAGCGCGAGT
AACAGCGCCCACGACCAGCTGCTGGCGTTTAACGTCAGCGTACCGTTGGATAAATTCCTCCCGCAAACGTGGGCCAGCTA
TGGCATGAACGCCAGCAAGAATGGTGGAACGACGCATAATATCGGCATGAACGGCGTCGCGCTGGAGAACAACTCGCTGA
ACTGGAACGTCCAGCAGGGTTACGGTACGGATGGCGTGGGTTACACCGGCAATATGAACGGTGACTATAAAGGGACGTAC
GGCGAAGTGACGGCGGGGTATAGCTACGACAAAAACAGCGAGCGTCTTAATTATGGTCTGCAGGGGGGCGTTATCGCCCA
CGCCGATGGCATCACGCTTTCCCAACCGCTCGGTGAAACCAATGCCCTGATAAAAGCCCCCGGCGCACACGGCGTGAATA
TTCGCAACCAACCCGGCGCGCGCACGGACTACCGGGGATATACGGTCGTCAGCAATATTTCCGTCTATCGAAAAAACGAC
CTGACGCTCGATCCGCAAAATATGCCTGAGGACGTAGAGCTGGAGATAAACACCGACACGGTTACCCCGACGCGAGGTGC
GGTGGTGCGCGCCGATTATCTTTCCAAAGTGGGGCGCAGGGTCCTGATGACCTTAACCGACAATAACCGCTTCGTGCCGT
TCGGGGCGGTGGTGACGCTTGCGGATGATAATAAGAGCAGCTTTATCGTTGGCGATCGCGGCCAGGTTTTTTTAAGCGGA
ATGCGCGAGCAGGGGGCAATCATCGTCACGTGGGGTCGCGAGTCCAGCCAACAGTGCCGTGCTGATTTCAGCCTGCCGAA
ACAATCAACCTACGCTGGAATAACAGAAGTTAGCGCCAGTTGTCACCAGGAACGTTAA

Protein sequence :
MTIKNNKLRPARLATLIAIALTGFSPELYASDSFNTALVELDNPGVGKADLSAFESGSQAPGTYHVDIILDDQLMDTRDI
PFSMAKNGGGNEVLQPCLSVEQLKQWGVKTELFPQLSVENSDCANLQAIPQASADFQFGAQRLVISIPQAAIDLPARGYV
PPEMWDEGITAALLNYSLSGANTRAKTGQGGRSDSQYANLRPGINIGPWRFRNYTTWSRESSGQDKWDTVYTYAQRAIIP
LKAQLTVGDSSAPADVFDSMPFRGGQLASDDDMLPDSLKGYAPVVRGIARTNAQVVVRQNGYQIYQSYVAPGAFEITDMY
PTGGAGDLDVTIKEADGSEQHFTLPYASLPVLQREARFKYAITGGQYRSYNSSVDKTPFGQTTAIYGLQHGFTLYGGLQE
SSKYQSLAFGVGKNMGALGAISTDVTQAWSTPDKTDKSRGQSWRARYSKNFIDTGTNFSIAGYRYSTSGYYGMQEVLDSY
GDSSALQDRRRNRAELTMSQTLSRELGSLTLSAAREDYWNSARSMASWSVGYNNYWRNISYGLTWTYSKNGSATSNDSAS
NSAHDQLLAFNVSVPLDKFLPQTWASYGMNASKNGGTTHNIGMNGVALENNSLNWNVQQGYGTDGVGYTGNMNGDYKGTY
GEVTAGYSYDKNSERLNYGLQGGVIAHADGITLSQPLGETNALIKAPGAHGVNIRNQPGARTDYRGYTVVSNISVYRKND
LTLDPQNMPEDVELEINTDTVTPTRGAVVRADYLSKVGRRVLMTLTDNNRFVPFGAVVTLADDNKSSFIVGDRGQVFLSG
MREQGAIIVTWGRESSQQCRADFSLPKQSTYAGITEVSASCHQER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fim2D AFH78429.1 putative fimbrial usher protein Virulence KpGI-5 Protein 2e-142 41
lpfC YP_006098365.1 fimbrial outer membrane usher protein Not tested Tn2411 Protein 6e-142 41
lpfC NP_839216.1 long polar fimbriae Not tested SHI-2 Protein 1e-142 41
lpfC NP_709462.1 long polar fimbriae Not tested SHI-2 Protein 1e-142 41
sfaF CAC16953.2 SfaF protein Virulence PAI III 536 Protein 4e-147 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
KOX_22805 YP_005020518.1 outer membrane usher protein LpfC VFG0454 Protein 9e-167 45
KOX_22805 YP_005020518.1 outer membrane usher protein LpfC VFG0876 Protein 3e-155 43
KOX_22805 YP_005020518.1 outer membrane usher protein LpfC VFG0446 Protein 2e-147 43
KOX_22805 YP_005020518.1 outer membrane usher protein LpfC VFG1645 Protein 2e-147 41
KOX_22805 YP_005020518.1 outer membrane usher protein LpfC VFG0912 Protein 8e-147 41