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Name : KOX_20630 (KOX_20630) Accession : YP_005020087.1 Strain : Klebsiella oxytoca KCTC 1686 Genome accession: NC_016612 Putative virulence/resistance : Virulence Product : yersiniabactin synthetase, HMWP2 component Function : - COG functional category : - COG ID : - EC number : - Position : 4458862 - 4464960 bp Length : 6099 bp Strand : + Note : COG1020 Non-ribosomal peptide synthetase modules and related proteins DNA sequence : ATGATTTCTGGCGCCCCCTCTCAGGATCCGCTGTTATCGGACAACGGCGAAGCGGCCGATTATCAACAATTACGCGAACT GTTAATACAGGAACTGAATGTAGCGCCGCAGCAGTTACAGGAAGAGAGCAATCTGATCCAGGCGGGCCTGGACTCCATAA GATTAATGAGATGGTTACACTGGTTTCGTAAAAAGGGCTACCGCCTCACCCTTCGCGAGCTGTATGCCGCCCCCACGTTG GCAGCATGGCGCCAGCTGATGCGCAGCCGTTCGGGTGAAAAACCGGATGATGCAAGCTCCCCGGCGGAGGCGGCGTGGCC AGTCATGAGCGAGGGTACCCCCTTCCCGCTGACGCCGGTACAGCATGCCTATCTGACGGGCCGAATGCCCGGACAGACGC TGGGCGGCGTCGGTTGCCATCTGTATCAGGAGTTTGCCGGCCATTATCTGACGGCGCCAAAGCTGGAGCAGGCTATCACG ATCTTACTGCAACGCCACCCGATGCTGCATATCGCCTTTCGCGCCGACGGGCAGCAGGTCTGGCTACCGCAGCCATACTG GAACGGCGTCACCGTTCATGATTTACGCCAGACCGACGAGGCAAGCCGCCAGGCCTATCTGGAAACATTGCGCCAGCGCC TGAGCCACCGTCTTTTACGCGTGGAAATGGGCGAAACCTTTGATTTCCAGTTGACGCTCTTGCCGGACAATTGCCACCGC CTCCATGTCAATATCGACCTGCTGATTATGGATGCTTCCAGCTTTACGCTGTTTTTCGATGAACTTAACGCCCTGCTGGC CGGAGAGTCGCTGCCGCCCGGCGACCCCCGCTATGATTTCCGCGCTTATCTGCTGCACCAGCAGAAGATCAATCAGCCGC TGCTCGACAAAGCGCGCGCGTACTGGCTGGCGAAAGCATCAATGCTGCCACCCGCGCCGGTTTTACCGCTAGCCTGCGAA CCCGCCACGCTGCGTGAAGTCCGTAATACCCGACGCCGCATGATTGTCCCGACAACACGCTGGAACGCCTTTAGCCAACG GGCCGGTGAGAATGGCGTGACGCCGACAATGGCGCTGGCGACCTGTTTTGCTGCCGTTCTGGGGCGCTGGGGCGGCCTGA CGCGGCTGCTGCTCAATATCACGTTATTTGACCGCCAGCCGCTGCACCCGGCGGTTGACGAAATGCTTGCCGACTTCACC AATATTCTTCTGCTGGATACCGCCTGCGATGGCGATACCGTCAGCAACCTGGCGCGTAAAAACCAGCTCACGTTTACTGA GGACTGGGAGCATCGCCACTGGTCCGGCGTCGAGCTCCTTCGTGAACTCAAACGCCAGCAAAGCCATCCCCACGGCGCCC CGGTGGTATTTACCAGCAATCTGGGGCGCTCCCTGTACAGCAGCCGCCCCGAGTCGCCGCTGGGCGAACCGGAATGGGGC ATCTCGCAGACGCCGCAGGTCTGGATAGATCATCTGGCGTTCGAGCATCGGGGCGAGGTCTGGCTACAATGGGATAGCAA TGACGCGTTGTTCCCTCCGGCGCTGGTCGAGACGTTGTTCAACGCCTACTGCCAGCTGATTAACCAACTCTGCGATGATG AAAGCGCCTGGAAGAAGCCGTTCGCGGACAGGATGCCCCAAAGCCAGCGGGAGATACGTCAACGGGTTAACGCAACCGAC GCACCCGTTCCTCAGGGCTTGCTGCATGAAGGCATTTTCCGCATCGCCCTCCGGCAACCGCAGGCGCTGGCGGTAACGGA CGCGCATTATCAGTGGAATTATCGTGAGCTGACCGAGAACGCACGCCGCTGCGCTGGCAGGTTAATCGCGTGCGGGGTTC AGCCCGGCGACAATGTCGCTATTACAATGTCGAAAGGCGCGGGGCAGCTGGTTGCGGTCCTCGCCGTTCTGCTGTCCGGG GCGGTGTACGTTCCGGTTTCGCTCGACCAGCCCGCCGCGCGGCGCGGGAAAATCTACGCTGACGCCAACGTCCGGCTGGT GCTCACCTGCCAGCACGACGCCAGCGCCTGGTCAGACGATATTCCCCACCTGACCTGGCAGCAGGCCATTGAGGCGGAGC CGCTAGCCGACCAGGCGGCGCACGCGCCGACGCAGCCGGCCTACATTATCTATACCTCCGGGTCGACCGGCACGCCGAAA GGCGTGGTCATTTCTCACCGTGCAGCGCTGAATACCTGCTGCGATATCAATAGCCGTTACCAGGTGGGTCCCGGAGACAG AGTGCTGGCCCTCTCCGCCCTGCATTTTGATTTATCGGTTTACGACATTTTTGGCGTTCTGAGCGCCGGCGGCTCGCTGG TTATCGTTATGGAAAATCAACGGCGCGATCCCCGCGCATGGTGCGAATTGATCCAGCGTCATCAGGTTACGCTCTGGAAC AGCGTCCCGGCGCTGTTCGATATGCTGTTGACCTGGTGTGAAGGTTTCGCCGACGCCGCGCCGGAGAAACTGCGGGCGGT CATGCTTTCCGGCGACTGGATCGGCCTCGATCTCCCAGCCCGCTATCACGCCTTCCGCCCCCAGGGACAGTTTATCGCCA TGGGCGGCGCCACCGAGGCGTCTATCTGGTCTAACGCCTGTGAAATTAACCGGGTCCCCGACCACTGGCGCGCCATCCCT TATGGCTTTCCGCTGGCCAACCAACGTTACCGGGTGGTGGATGAACTGGGCCGGGACTGCCCGGACTGGGTACCGGGCGA ATTGTGGATTGGCGGTATCGGGGTCGCGGAAGGCTACTTTAACGATCCTGTACGCAGCGAGCAGCAGTTTGTAACGCAAT CGAACGCGCGCTGGTATCGCACCGGCGATCTCGGGTGCTACTGGCCAGACGGTACGTTAGAGTTCCTCGGTCGTCGCGAT AAGCAGGTCAAAGTCGGGGGATATCGCATCGAGCTGGGTGAAATCGAAAGCGCGCTCAGCCAGCTGGCGGGAGTGAAACA GTCAACCGTTGTGGCGATCGGCGAAAAAGAAAAGACCCTGGCGGCCTGGGTTGTGCCTCAGGGTTCGGCTTTCTGTGTTA CCCATCATCGGGACCCGGCGCTGCCCCAGGCGTGGCGCGGGCTTGCCGGAACGCTGCCCTGCTGCGTCTGCCCCCCGGAA ATCTCCGCCGGCCAGGTCGCTGATTTTCTTCAGCATCGCCTGTTAAAACTGAAACCGGGTCAAACTCCTGGCGCCGATCC TCTTCCCCTGATGAATGCTCTCGCTATCCAGCCTCGCTGGCGGGCCGTGGTGGAACGCTGGTTAGCCTTTCTCGTGACCC AACAGCGGCTGCAGCCCGCCGCTGAGGGTTATCAGGTTTGTGCGGGGGAAGCGCCGGAGAATGACCCTCCTTCTTTCAGC GGGCATGACCTCACCTTAACGCAGATCCTTCGCGGCGCTCGCCACGAACTGTCATTACTGAACGATGCGCGGTGGTCGCC GGAAAGTCTGGCTTTCGACCATCCGGCCAGCGCCCTGTATATCGAGGAACTGGCGACAATCTGTCAACAGCTTTCCCGGC GTTTACAGCGCCCGGTACGCCTGCTAGAGGTGGGTGTCCGCACCGCCCGCGCCGCAGAGTGCCTGCTAACCCGGCTCAGC GCTGACGAGATTGAGTATGTCGGGCTTGAGCACAGCCAGGAGCTGCTGCTGAGCGCCCGACAGCGGCTTGCACCGTGGTC TGACGCCCGTCTGGCCCTCTGGAGTGCAGACACGCTGACGGCGCATGCTCATTCGGCGGACATTATCTGGCTGAATAACG CCCTGCATCGTCTGCTGCCGGAAGAGCCCGGGCTCCTCGCGGCATTACAGCAGCTGGCCGTTCCAGGCGCGCTGCTCTAC GTGTTGGAGTTTCGTCAGTTAACGCCCTCCGCCCTGCTCAGCACGCTTCTGTTAACCGATGGTCAGCCCGAAGCCTTACT TCACAATAGCGCTGACTGGGGGGCGATATTTACCGCCGCCGCTTTCAACTGCCAGCACGGCGATGAAGTCGAGGGATTGC AGCGCTTCCTCGTACAATGCCCCGTTAGCCAGGTACGCCGCGATCCTCGTCAGCTGCAGTCCGCTCTCGCCGAACGTCTG CCGGGGTGGATGGTACCGAAACGGATCTTCTTACTTGACGCCTTACCGCTGACGGCGAACGGCAAAATTGACTATCAGAC GCTAAAGCGCTGTCATACCCCGGAAGCTGAAAACCGGACTGAAGCGGATTTACCCCTGGGCGATATTGAGAAGCAGGTTG CCGTCATCTGGCAGCCGCTCTTGTCGATGGGCGCCGTCAGCAGAGAAACCGACTTCTTCCAGCATGGCGGTGATAGCCTG CTAGCCACCAGGCTGATCGGACAGCTCCACCAGGCGGGTTATGAAGCACGATTAAGCGACCTGTTTAATCACCCCCGGCT GGCTGATTTTGCCGCCACGCTGCGTAAAACCGACCTCCCTGTTGAACAACCCTTTGTCCACTCCCCTGAAGAACGCTACC GGCCTTTCGCGCTGACTGATGTGCAGCAGGCTTACCTGGTCGGGCGTCAGCCGGGCTTTGCCCTTGGCGGCGTAGGCTCA CACTTCTTTGTTGAATTTGAAATTGCCGATCTGGATATTCACCGGCTGGAGAAGGTCTGGAACCGGTTAATCGCCCGCCA CGATATGCTGCGCGCCGTGGTGCGGGATGGACAACAGCGGGTTCTCGAACAGACTCCCCCGTGGGTGATACCCGCGCACA TCCTGCACAGCCCCGAAGAGGCGCTGCAGGTACGCGACAGACTGGCGCATCAGGTTCTCAACCCTGAAGTATGGCCGGTA TTCGATCTCCAGGTCGGGTTCGTCGACGGGATGCCCGCCCGCCTGTGGCTGTGTCTGGATAACCTGTTGCTTGACGGGTT GAGCATGCAGATCCTGTTGTCAGAGCTGGAACACGGCTATCGCTATCCGCAGCAGCTGCCGCCGCCGCTTCCCGTTACCT TCAGGGATTATCTGCAGCAACCCGCGCTGCGGACGCCCAATCCCGACTCTCTGGCATGGTGGCAAACGCAGCTTGATGAT ATTCCTCCGGCGCCTGCGTTACCGCTACGCTGCTTGCCTCAGGACGTTGAGACGCCGCGCTTCGCACGGCTCTATGGGGC AATGGACAGCGCGCGCTGGCGTCGCCTGAAACAGCGGGCGGCTGACGCTCATCTCACCCCGTCGGCCGTACTGTTATCCG TGTGGTCAACGGTTCTTGCTGCATGGAGCGCACAGCCCGATTTCACGCTTAACCTTACGCTTTTCGACAGACGACCGCTG CACCCGCAAATCAACCAGATCCTGGGCGACTTTACTTCGCTGATGCTGCTGAGCTGGCATCCCGGCGAGAGCTGGCTGCA AAGCGCGCGGTTATTACAGCAGCGACTAAGCGAGAGCCTCAACCACCGCGATGTGTCGGCAATCCGCGTGATGCGGCAAC TGGCGCGGCGGCAAAACGTACCGGCTGTCCCAATGCCCGTCGTCTTTACCAGCGCGCTGGGCTTTGAGCAGGATAACTTC CTTGCCCGGCGCAATCTGCTCAAACCGGTGTGGGGTATATCCCAGACGCCGCAGGTCTGGCTCGATCACCAGGTTTATGA ATCCGAAGGGGAACTGCGCTTTAACTGGGATTTTGTCGCCGCCCTGTTTCCTGACGGGCAGGTGGAGCGCCAGTTTGCAC AGTATTGCGCGTTGCTTAACCGAATGGCGGAGGATGACAGCAGCTGGCAGCTGCCGCTCGCCGACCTGGTTCCCCCGCTT AAGGTCACGGAGCGACGCGCCCGCCGGCTGCGCCCTGAGCGCGCTCAGCCGCGGATCGCGGCGGACAAGAGCAGCGTCAG CCTGATTTGCGACACCTTTCGCGAGGTGGTTGGCGAGCCTGTCGCACCCGCAGAGAACTTTTTTGAGGCGGGCGCCACGT CGCTGAATCTGGTGCAGCTGCACGTCTTGTTACAACGTCACGAATTCGCCACCCTGACGCTGCTTGACCTGTTCACTCAC CCTTCTCCTGTCGCGCTGGCCAATTATCTCGCCGGCGTAGCCCTGAAGGAGAAAACCAAACGCGTGCGGCCGGTTCGCCG TCGTCAGCGGCGCATTTGA Protein sequence : MISGAPSQDPLLSDNGEAADYQQLRELLIQELNVAPQQLQEESNLIQAGLDSIRLMRWLHWFRKKGYRLTLRELYAAPTL AAWRQLMRSRSGEKPDDASSPAEAAWPVMSEGTPFPLTPVQHAYLTGRMPGQTLGGVGCHLYQEFAGHYLTAPKLEQAIT ILLQRHPMLHIAFRADGQQVWLPQPYWNGVTVHDLRQTDEASRQAYLETLRQRLSHRLLRVEMGETFDFQLTLLPDNCHR LHVNIDLLIMDASSFTLFFDELNALLAGESLPPGDPRYDFRAYLLHQQKINQPLLDKARAYWLAKASMLPPAPVLPLACE PATLREVRNTRRRMIVPTTRWNAFSQRAGENGVTPTMALATCFAAVLGRWGGLTRLLLNITLFDRQPLHPAVDEMLADFT NILLLDTACDGDTVSNLARKNQLTFTEDWEHRHWSGVELLRELKRQQSHPHGAPVVFTSNLGRSLYSSRPESPLGEPEWG ISQTPQVWIDHLAFEHRGEVWLQWDSNDALFPPALVETLFNAYCQLINQLCDDESAWKKPFADRMPQSQREIRQRVNATD APVPQGLLHEGIFRIALRQPQALAVTDAHYQWNYRELTENARRCAGRLIACGVQPGDNVAITMSKGAGQLVAVLAVLLSG AVYVPVSLDQPAARRGKIYADANVRLVLTCQHDASAWSDDIPHLTWQQAIEAEPLADQAAHAPTQPAYIIYTSGSTGTPK GVVISHRAALNTCCDINSRYQVGPGDRVLALSALHFDLSVYDIFGVLSAGGSLVIVMENQRRDPRAWCELIQRHQVTLWN SVPALFDMLLTWCEGFADAAPEKLRAVMLSGDWIGLDLPARYHAFRPQGQFIAMGGATEASIWSNACEINRVPDHWRAIP YGFPLANQRYRVVDELGRDCPDWVPGELWIGGIGVAEGYFNDPVRSEQQFVTQSNARWYRTGDLGCYWPDGTLEFLGRRD KQVKVGGYRIELGEIESALSQLAGVKQSTVVAIGEKEKTLAAWVVPQGSAFCVTHHRDPALPQAWRGLAGTLPCCVCPPE ISAGQVADFLQHRLLKLKPGQTPGADPLPLMNALAIQPRWRAVVERWLAFLVTQQRLQPAAEGYQVCAGEAPENDPPSFS GHDLTLTQILRGARHELSLLNDARWSPESLAFDHPASALYIEELATICQQLSRRLQRPVRLLEVGVRTARAAECLLTRLS ADEIEYVGLEHSQELLLSARQRLAPWSDARLALWSADTLTAHAHSADIIWLNNALHRLLPEEPGLLAALQQLAVPGALLY VLEFRQLTPSALLSTLLLTDGQPEALLHNSADWGAIFTAAAFNCQHGDEVEGLQRFLVQCPVSQVRRDPRQLQSALAERL PGWMVPKRIFLLDALPLTANGKIDYQTLKRCHTPEAENRTEADLPLGDIEKQVAVIWQPLLSMGAVSRETDFFQHGGDSL LATRLIGQLHQAGYEARLSDLFNHPRLADFAATLRKTDLPVEQPFVHSPEERYRPFALTDVQQAYLVGRQPGFALGGVGS HFFVEFEIADLDIHRLEKVWNRLIARHDMLRAVVRDGQQRVLEQTPPWVIPAHILHSPEEALQVRDRLAHQVLNPEVWPV FDLQVGFVDGMPARLWLCLDNLLLDGLSMQILLSELEHGYRYPQQLPPPLPVTFRDYLQQPALRTPNPDSLAWWQTQLDD IPPAPALPLRCLPQDVETPRFARLYGAMDSARWRRLKQRAADAHLTPSAVLLSVWSTVLAAWSAQPDFTLNLTLFDRRPL HPQINQILGDFTSLMLLSWHPGESWLQSARLLQQRLSESLNHRDVSAIRVMRQLARRQNVPAVPMPVVFTSALGFEQDNF LARRNLLKPVWGISQTPQVWLDHQVYESEGELRFNWDFVAALFPDGQVERQFAQYCALLNRMAEDDSSWQLPLADLVPPL KVTERRARRLRPERAQPRIAADKSSVSLICDTFREVVGEPVAPAENFFEAGATSLNLVQLHVLLQRHEFATLTLLDLFTH PSPVALANYLAGVALKEKTKRVRPVRRRQRRI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| irp2 | YP_002346902.1 | yersiniabactin biosynthetic protein | Virulence | HPI | Protein | 0.0 | 88 |
| irp2 | NP_669706.1 | HMWP2 nonribosomal peptide synthetase | Virulence | HPI | Protein | 0.0 | 88 |
| irp2 | YP_070124.1 | yersiniabactin biosynthetic protein | Virulence | HPI | Protein | 0.0 | 88 |
| irp2 | CAA21390.1 | - | Virulence | HPI | Protein | 0.0 | 88 |
| irp2 | YP_853075.1 | yersiniabactin biosynthetic protein | Virulence | PAI IV APEC-O1 | Protein | 0.0 | 88 |
| irp2 | NP_993007.1 | yersiniabactin biosynthetic protein | Virulence | HPI | Protein | 0.0 | 88 |
| irp2 | YP_001006815.1 | yersiniabactin biosynthetic protein | Virulence | HPI | Protein | 0.0 | 87 |
| PMI2599 | YP_002152317.1 | non-ribosomal peptide synthase | Not tested | Not named | Protein | 0.0 | 41 |
