Gene Information

Name : KOX_18080 (KOX_18080)
Accession : YP_005019577.1
Strain : Klebsiella oxytoca KCTC 1686
Genome accession: NC_016612
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3912789 - 3914744 bp
Length : 1956 bp
Strand : +
Note : COG0550 Topoisomerase IA

DNA sequence :
ATGCGGCTGTTTATTGCAGAAAAACCGAGTCTCGGTCGCGCCATCGCCGATGTGCTGCCAAAACCGCATCGCAAAGGCGA
CGGCTACATTGAGTGCGGTAACGGGCAGGTGGTCACGTGGTGCATCGGCCACCTGCTGGAGCAGGCCCAGCCCGACGTCT
ACGATGCGCGCTATGCGCGCTGGAACCTGCTCGACTTGCCTATCGTGCCGGAAAAGTGGCAGCTGCAGCCTAAACCGTCG
GTGACCAAACAGCTTAACGTGATTAAGCGTCTGCTCGGCGATGCGCAGGAAGTCATTCATGCGGGTGACCCGGACAGAGA
GGGGCAGCTGCTGGTGGATGAGGTACTTGACTACCTGCAGCTGGCGCCGGAAAAGCGTCAGCAGGTGCAGCGCTGTCTGA
TTAACGATCTTAACCCGCAGGCGGTGGAGCGGGCGATTAACCGCCTGCGCGCCAACAGCGAATTTGTTCCGCTGTGCGTC
TCCGCGCTGGCCCGCGCCCGCGCCGACTGGCTATACGGGATCAATATGACCCGCGCGTACACCATCCTTGGCCGTAACGC
GGGTTACCAGGGGGTACTCTCGGTCGGGCGCGTGCAAACGCCGGTGCTTGGCCTGGTGGTACGCCGCGATGAAGAGATTG
AAAACTTCGTCGCTAAAGACTTCTTCGACGTCAAGGCGCATATCGTTACCCCCAAGGATGAGCGTTTTGTCGCCACCTGG
GTGCCCAGCGAGGCCTGTGAACCGTACCAGGATGAAGAGGGGCGACTGCTGCATCGCTCGCTTGCCGAGCACGTCGTCAA
GCGCATTGAGGGGCAGCCGGCGACGGTCACCGCTTATAACGATAAGCGGGACTCTGAGCCAGCGCCGCTGCCATTCTCCC
TCTCGGCGCTGCAGATTGAAGCCGCGAAGCGCTTCGGCTTTAGCGCGCAGAACGTGCTGGATATCTGCCAGAAGCTGTAC
GAAACCCATAAGCTGATTACCTATCCGCGTTCGGATAGCCGCTATCTGCCGGAGGAGCATTTTGCCGGGCGCCATGCGGT
GCTGAACGCGATCGGCGTGCACGCGGCGGATCTGCTGCCGCAGCCGGTGGTGGATCCGGAGATCCGTAACCGCTGCTGGG
ACGATAAAAAGGTCGATGCCCACCACGCGATTATTCCGACCGCCCGCAGTTCGCAGGTAAAACTCAGCGACAACGAAGAA
AAGGTTTACGGCCTGATTGCCCGCCAGTATCTGATGCAGTTCTGCCCGGATGCGGTGTTCCGCAAATGCCAGATCGATCT
CGATATCGCCAACGGCAAGTTCGTTGCCAAAGCGCGTTTTCTGGCGGAAGCGGGCTGGCGAACCCTGCTGGGCAATAAAG
AGCGCGATGAAGAGAACGACGGCATGCCGCTGCCGGTGGTGGCAAAGGATGACGAGCTGCTGTGCGAAAAAGGCGAAGTG
GTGGAGCGTCAGACCCAGCCGCCGCGTCATTTTACCGATGCGACGCTGCTATCGGCGATGACCGGTATTGCCCGCTTTGT
GCAGGATAAAGACCTGAAGAAAATCCTGCGCGCAACGGATGGCCTCGGTACGGAGGCAACCCGCGCCGGGATTATCGAAC
TGTTGTTCAAACGCGGCTTCTTAACCAAGAAAGGGCGCTATATCCACTCCACCGACGCCGGGAAGGCGCTGTTCCACTCT
TTGCCTGAAATGGCGACGCGCCCGGATATGACCGCCCACTGGGAATCGATTCTGACGCAAATCAGCGAGAAACAGTGCCG
CTATCAGGACTTTATGCAGCCGCTGGTCGGTACCCTGTTCCAGCTTATCGACCAGGCCAGGAGCACGCCGGTACGCCGCT
TCCGCGGAATTGTGGCCCCGGGCGACGGCAAGAAGAGCTTTAGCAAGGGGAAAGGCAGAGCCAAAGCGAAAGATAAAAAA
AGCGCCGCCGGCCCTGCGGCGGAAAGTCCGCAATAA

Protein sequence :
MRLFIAEKPSLGRAIADVLPKPHRKGDGYIECGNGQVVTWCIGHLLEQAQPDVYDARYARWNLLDLPIVPEKWQLQPKPS
VTKQLNVIKRLLGDAQEVIHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAINRLRANSEFVPLCV
SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFDVKAHIVTPKDERFVATW
VPSEACEPYQDEEGRLLHRSLAEHVVKRIEGQPATVTAYNDKRDSEPAPLPFSLSALQIEAAKRFGFSAQNVLDICQKLY
ETHKLITYPRSDSRYLPEEHFAGRHAVLNAIGVHAADLLPQPVVDPEIRNRCWDDKKVDAHHAIIPTARSSQVKLSDNEE
KVYGLIARQYLMQFCPDAVFRKCQIDLDIANGKFVAKARFLAEAGWRTLLGNKERDEENDGMPLPVVAKDDELLCEKGEV
VERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHS
LPEMATRPDMTAHWESILTQISEKQCRYQDFMQPLVGTLFQLIDQARSTPVRRFRGIVAPGDGKKSFSKGKGRAKAKDKK
SAAGPAAESPQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 4e-109 41
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 4e-109 41
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 3e-109 41
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 7e-105 41
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 4e-109 41