Gene Information

Name : KOX_13815 (KOX_13815)
Accession : YP_005018726.1
Strain : Klebsiella oxytoca KCTC 1686
Genome accession: NC_016612
Putative virulence/resistance : Virulence
Product : betaine aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2990143 - 2991615 bp
Length : 1473 bp
Strand : -
Note : COG1012 NAD-dependent aldehyde dehydrogenases

DNA sequence :
ATGTCCCGAATGGCCGAACAGCAGCTTTACATCGACGGTGGTTATGTTTCCGCCACCAGCGGTAAAACCTTCGAGACGAT
TAACCCCGCCAGCGGGGAAGTGCTGGCGACCGTCCAGGCCGCCGGCCGCGAAGACGTCGACCGGGCGGTAAAGAGCGCCC
AAAAAGGGCAAAAAATCTGGGCGGCGATGAGCGCCATGGAACGTTCGCGCATTCTGCGTAAAGCGGTCGATATTCTGCGC
GATCGCAACGATGAACTGGCGCGTCTGGAGACTCTCGATACCGGCAAACCGCTGAGCGAAACCGCCGCCGTCGATATCGT
CACCGGCGCCGATGTGCTGGAGTACTACGCGGGCCTGATCCCGGCGCTGGAAGGGAGCCAGATCCCGCTGCGCGATAGTT
CATTCGCCTACACCCGCCGGGAACCGCTGGGCGTCGTCGCCGGGATCGGCGCCTGGAACTACCCGATCCAGATCGCCTTG
TGGAAATCAGCCCCGGCGCTGGCGGCCGGTAACGCGATGATCTTTAAGCCGAGTGAAGTCACCCCGCTCACCGCCCTGAA
GCTGGCGGAAATTTACCGCGAGGCGGGACTGCCGGCGGGGGTATTTAACGTGCTGCCGGGCACGGGCGCCGAAACCGGCC
AGTATCTCACCGAGCACCCGGACATCGCCAAAATCTCCTTTACCGGCGGCGTCGCCAGCGGCAAAAAAGTGATGGCCAAC
TCCGCCGCCTCCTCGCTGAAGGAAGTCACCATGGAGCTGGGCGGTAAATCGCCGCTGATCGTCTGCGAAGACGCCAACCT
CGACCTCGCCGCCGACATCGCGATGATGGCTAACTTCTATAGCTCAGGACAGGTCTGCACCAACGGCACCCGGGTATTCG
TTCCGGCGCGCCTGAAGGCGGCGTTTGAAGAGAAAATCCTCGCTCGCGTGGCGCGTATCCGCCCCGGCGATCCGTTTGCT
GAAAGCACCAACTTCGGGCCGCTGGTGAGCTTCCCGCACCGCGATAACGTGCTGCGCTACATCGCGATCGGCAAGCAAGA
AGGCGCGCGCCTGCTCTGCGGCGGCGAGGTGCTGAAAGGCGAAGGCTTCGACCGCGGCGCGTGGGTCGCCCCGACGGTGT
TTACCGACTGCGATGACCAGATGACCATCGTCCGCGAAGAGATCTTCGGCCCGGTGATGTCGATTCTGAGCTACGACGAT
GAGGAAGAAGCGGTTCGCCGCGCCAACGCCACCGAATACGGCCTCGCCGCCGGCGTCGTCACGCCGGATTTAAACCGCGC
CCATCGCCTGATTCATCGGCTGGAGGCCGGGATCTGCTGGATCAACACCTGGGGTGAATCCCCGGCGGAGATGCCGGTCG
GCGGCTACAAGCACTCCGGTATTGGCCGCGAAAACGGCGTGCAGACGCTGCACAGCTACACCCAGATAAAATCCATCCAG
GTTGAGATGGGTCAGTTTCAATCCATATTTTAA

Protein sequence :
MSRMAEQQLYIDGGYVSATSGKTFETINPASGEVLATVQAAGREDVDRAVKSAQKGQKIWAAMSAMERSRILRKAVDILR
DRNDELARLETLDTGKPLSETAAVDIVTGADVLEYYAGLIPALEGSQIPLRDSSFAYTRREPLGVVAGIGAWNYPIQIAL
WKSAPALAAGNAMIFKPSEVTPLTALKLAEIYREAGLPAGVFNVLPGTGAETGQYLTEHPDIAKISFTGGVASGKKVMAN
SAASSLKEVTMELGGKSPLIVCEDANLDLAADIAMMANFYSSGQVCTNGTRVFVPARLKAAFEEKILARVARIRPGDPFA
ESTNFGPLVSFPHRDNVLRYIAIGKQEGARLLCGGEVLKGEGFDRGAWVAPTVFTDCDDQMTIVREEIFGPVMSILSYDD
EEEAVRRANATEYGLAAGVVTPDLNRAHRLIHRLEAGICWINTWGESPAEMPVGGYKHSGIGRENGVQTLHSYTQIKSIQ
VEMGQFQSIF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 6e-70 41
hpaE AAO17179.1 HpaE Not tested tcd island Protein 4e-76 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-71 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-71 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-71 41
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 4e-73 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-71 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
KOX_13815 YP_005018726.1 betaine aldehyde dehydrogenase VFG0082 Protein 3e-70 41