Gene Information

Name : clpC (BFO_1740)
Accession : YP_005014610.1
Strain : Tannerella forsythia ATCC 43037
Genome accession: NC_016610
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence ClpC/MecB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1853233 - 1855797 bp
Length : 2565 bp
Strand : -
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728

DNA sequence :
ATGAAGAACAATTATTCAAAAAAAGTGATCGACGTGATTGAATACAGTCGCGAAGAGGCTGCTCGTTTACAGAACAGCTA
CATTGGTCCGGAGCATTTGATGCTGGGCCTGCTGCGCGAAGGCAATGGGAACGCCGTAACCATTCTTCAGGAGATGAATG
CGGACTTGACACAGATCAAAAAAGAGATCGAACACGAAATACGAAATACGTATGAAACGGGCGAAATGCCACTCAATGAT
ATTACCATCAGCAAAAGTACCGAACGTGTATTGCGCATGAGCATGCTCGAAGCCCGGATCTTTAAAAGCGAACGTACGCG
AACCGAACACCTGCTGCTGGCACTCCTGAAAGAGGAGTTTAATACGGCGGCACAGATTTTGGGACGAACGGGTATTGATT
ATCACGCCGTCTACGGTCGCGTGAGCGGTGAATCCGATATCGATATCGCGGAGATCGAAGAAGTTCGCGACGGGTTTACC
GACGATGATGAGGAAGAAGACGATGCCTTTTCATCGTCGTATTCTTCGTCTTCCTCGGGGCAGTCGACACCGGGAGGCAT
GGTGCGCGGCGCAGCCGGCACTTCGCAGAAAGTGTCGAACGATACGCCGGTGCTCGACAATTTCGGCTCGGATATGACGC
GGGCGGCTGCCGAAGGAAAGTTGGACCCGATCGTTGGACGCGAGAAGGAGATTGAACGGCTGGCACAGATTCTGAGCCGT
CGGAAGAAGAACAATCCCGTGCTGATCGGCGAGCCGGGCGTCGGGAAATCGGCGATTGTCGAAGGGCTGGCACAGCGCAT
CGTTCAGCGCAAGGTGTCGCGCATCCTGTTCGACAAGCGGGTGATTAGCCTCGACATGGCCTCCATCGTGGCCGGAACGA
AGTATCGCGGGCAGTTTGAAGAGCGCATCAAGGCCGTACTGAACGAGCTGACAAAAAATCCGAATATCATTCTGTTCATC
GACGAAATCCACACGCTTGTCGGGGCCGGTTCGGCTTCGGGCTCAATGGATGCCGCCAATATGCTTAAGCCTGCATTGGC
ACGGGGTGAGCTGCAATGTATCGGCGCTACGACACTCGATGAGTATCGGAAGAACATCGAGAAGGACGGAGCATTGGAAC
GCCGTTTCCAGAAGGTGCTCGTCGACCCGACCACCCCCGAAGAAACCTTGCAGATTCTCAAAAATATCAAGGAACGGTAT
GAAGAACATCATCATATGATCTATACCGATGCGGCGCTTGAAGCATGTGTCAAACTGACGGAACGCTACATCAGCGACCG
CAATCTCCCCGACAAGGCCATCGATGCACTGGACGAGGCCGGATCACGCGTGCATATCTCGACCATTGTCGTACCCCGGC
ATATCGAAGAGCTGGAAGCGAAGATCGAAGCGACCCGAAATGACAAACTAGCGGCTGTGAAATCGCAGAATTTTGAGCTG
GCGGCAAGCCATCGCGATACCGAACGGCAATACATCATCGAACTGGAAGCGGCCAAGCATAAATGGGAAGAAGAGATGCA
GGAACATCGCGAGACGGTCGATGCCGAGCAAGTGGCGGAGGTGGTGGCGATGATGTCGGGAGTACCCGTGCAACGTATTG
CACAGACGGAAAACATACGACTGCGTGACATGGGGGCACTGCTCAAGGAAAAGATCATCGGGCAAGATGAAGCCGTAGAA
AAGATCGTTAAAGCCATTCAGCGTAACCGCGTCGGACTGAAAGACCCGAACAAACCCATCGGCACCTTCATGTTCTTAGG
ACCTACGGGAGTAGGCAAAACGCATCTGGCCAAAAAACTGGCCGAGTTCCTGTTCGACACACCCGATGCGCTGATCCGAA
TCGACATGAGCGAGTACCTTGAAAAGTTCGCCGTCTCGCGTCTTATCGGAGCACCTCCGGGATACGTCGGCTATGAAGAA
GGCGGACAGCTGACCGAAAAGGTGCGTCGCAAACCCTATTCCGTTGTGCTGCTCGACGAGATCGAGAAAGCGCACCCCGA
CGTGTTCAACCTCTTGCTTCAGGTGCTCGACGAGGGACGGCTGACCGACAGCCTCGGACGCCGCATTGACTTCAAAAATA
CGATTCTGATCATGACATCCAATATCGGGACGCGCCAGTTAAAAGACTTCGGACGGGGCATCGGCTTCCATCCGCAGCGA
CAGGGGCTGATGGACAAAGATTATTCGCGCGGCGTGATTCGTAAAGCGCTGGAAAAGTCGTTCGCACCCGAATTTCTGAA
CCGTATCGACGATATTGTCATGTTCGATCCGCTGGACAAAACCTCGATTCACCGGATTATTGACATCGAACTGAAAGAAG
TCTATCGACGGATCGACGAGCTCGGCTACCGTCTGGAAATTACGGACGAAGCGAAGGAATACATCACCTCGAAAGGCTAT
GATGTCCAGTTCGGTGCACGGCCGCTGAAACGCTCGATCCAGAAATATATCGAAGACGAGATGGCCGGCATCCTTCTGCA
GGAAGATGTGACGCCGGGTGATACGATCGTAATCGGGCATGATCAGGCAACCGACAAAATGACACACGAAATCAAAAAGG
CGTGA

Protein sequence :
MKNNYSKKVIDVIEYSREEAARLQNSYIGPEHLMLGLLREGNGNAVTILQEMNADLTQIKKEIEHEIRNTYETGEMPLND
ITISKSTERVLRMSMLEARIFKSERTRTEHLLLALLKEEFNTAAQILGRTGIDYHAVYGRVSGESDIDIAEIEEVRDGFT
DDDEEEDDAFSSSYSSSSSGQSTPGGMVRGAAGTSQKVSNDTPVLDNFGSDMTRAAAEGKLDPIVGREKEIERLAQILSR
RKKNNPVLIGEPGVGKSAIVEGLAQRIVQRKVSRILFDKRVISLDMASIVAGTKYRGQFEERIKAVLNELTKNPNIILFI
DEIHTLVGAGSASGSMDAANMLKPALARGELQCIGATTLDEYRKNIEKDGALERRFQKVLVDPTTPEETLQILKNIKERY
EEHHHMIYTDAALEACVKLTERYISDRNLPDKAIDALDEAGSRVHISTIVVPRHIEELEAKIEATRNDKLAAVKSQNFEL
AASHRDTERQYIIELEAAKHKWEEEMQEHRETVDAEQVAEVVAMMSGVPVQRIAQTENIRLRDMGALLKEKIIGQDEAVE
KIVKAIQRNRVGLKDPNKPIGTFMFLGPTGVGKTHLAKKLAEFLFDTPDALIRIDMSEYLEKFAVSRLIGAPPGYVGYEE
GGQLTEKVRRKPYSVVLLDEIEKAHPDVFNLLLQVLDEGRLTDSLGRRIDFKNTILIMTSNIGTRQLKDFGRGIGFHPQR
QGLMDKDYSRGVIRKALEKSFAPEFLNRIDDIVMFDPLDKTSIHRIIDIELKEVYRRIDELGYRLEITDEAKEYITSKGY
DVQFGARPLKRSIQKYIEDEMAGILLQEDVTPGDTIVIGHDQATDKMTHEIKKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 9e-163 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_005014610.1 negative regulator of genetic competence ClpC/MecB VFG0079 Protein 9e-177 55
clpC YP_005014610.1 negative regulator of genetic competence ClpC/MecB VFG0080 Protein 8e-148 49