Gene Information

Name : MycrhN_4835 (MycrhN_4835)
Accession : YP_005002531.1
Strain : Mycobacterium rhodesiae NBB3
Genome accession: NC_016604
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4895731 - 4897452 bp
Length : 1722 bp
Strand : +
Note : PFAM: Urease alpha-subunit, N-terminal domain; Amidohydrolase family; TIGRFAM: urease, alpha subunit

DNA sequence :
ATGACGGGTATCTCGCGGGCACGATACAAGGCGCTCTACGGACCCACCACGGGCGATCGCATCCGGCTGGCCGACACCGA
TCTGCTCGTCGAGATCACCGAGGACCGCAGCGGCGGACCGGGGTTGGCGGGTGACGAGGCGGTGTTCGGCGGCGGCAAGG
TATTGCGTGAGTCGATGGGGCAGGGTCGGGTGACGCGGGCCGACGGCGCACCGGACACGGTGATCACCGGTGCGGTGATC
ATCGACCACTGGGGGATCATCAAGGCGGATATCGGAATTCGTGACGGCCGGATCACCGCGATCGGCAAGGCCGGCAATCC
CGACGTCATGTCCGGGGTACATCCCGACTTGGTGGTTGGGCCGTCGACCGAGATCATCTCCGGCAACGGCCGAATCGTGA
CCGCCGGTGGCATCGACTGTCACGTGCACCTGATCTGTCCGCAGATCAAGGAAGAGGCCCTCGGCGGCGGAATCACCACC
ATCGTCGCCGGCGGCACCGGGCCTGCGGAGGGCAGCAAGGCCACGACGGTCACTCCAGGGTCATGGCATCTGGGCCGCAT
GCTCGAGGCGCTGGACTCATGGCCGATGAACATCGCGTTGCTCGGCAAGGGAAACACCGTCAGCGCCGAATCGATGTGGG
AGCAGTTACGCGGCGGCGCTGCCGCTTTCAAGCTGCACGAGGACTGGGGTACGACTCCGGCGGCGATAGACGCCTGCCTC
GCCGTCGCCGACGAGTCCGGAGTCCAGGTGAACATCCACACCGACACCCTCAACGAGATGGGCTTCGTCGAGGACACCCT
AGCCGCCATCAAGGGACGCTCGATTCACGCGTATCACACCGAGGGCGCAGGCGGCGGCCACGCGCCCGACATCATCACGG
TTGCCTCCCACCCCAACGTGCTGCCCAGTTCCACCAACCCGACGCGCCCGCACACCGTCAACACGCTCGACGAACACCTC
GACATGTTGATGGTGTGCCATCACCTCAACCCGGCGGTGCCAGAAGATCTTTCGTTCGCCGAAAGCCGCATCCGACCCTC
GACGATGGCTGCCGAGGACCTGCTGCACGACATCGGCGCGATTTCGATGATCGGCAGTGACTCCCAGGCCATGGGTCGCA
TCGGGGAGGTGGTGATCCGCACCTGGCAGACCGCGCACGTGATGAAGCGACGTCGTGGTGCGCTCCCCGGAGACGGCGCC
GCCGACAACAACCGGGCACGCCGCTACGTCGCCAAGTACACGATCTGCCCGGCCGTCGCGCACGGACTCGACCACGAGGT
CGGCTCCGTGGAGGTCGGCAAGCTCGCCGATCTCGTGCTGTGGGAGCCCGCGTTCTTCGGAGTGCGTCCGCACGTCGTGC
TGAAGGGCGGCATGATCGCGTGGGCGGCCATGGGCGACGCGAACGCGTCGATCCCCACTCCGCAACCGGTTCTGCCCCGG
CCGATGTTCGGCGCCGCACCCGCCGCGGCCGCGGCCACATCTGTGCACTTCGTATCCCAGCAGGCCGTCGACGACGGCTT
GGCCGGACGCCTCGCCGTCAGCCGCAGGCTTGTGGCGGTCCGCAACGTCCGCGGCGTCGGCAAGGCCCAGATGCCGCTCA
ACGACACCCTTCCCGAGATCGAGGTCGACCCGGACACCTTCACCGTGCGCATCGACGGTGACGTGTGGCAGGAAGATCCT
GCGGTCGACCTGCCGATGGCACAGCGATACTTCCTGTTCTGA

Protein sequence :
MTGISRARYKALYGPTTGDRIRLADTDLLVEITEDRSGGPGLAGDEAVFGGGKVLRESMGQGRVTRADGAPDTVITGAVI
IDHWGIIKADIGIRDGRITAIGKAGNPDVMSGVHPDLVVGPSTEIISGNGRIVTAGGIDCHVHLICPQIKEEALGGGITT
IVAGGTGPAEGSKATTVTPGSWHLGRMLEALDSWPMNIALLGKGNTVSAESMWEQLRGGAAAFKLHEDWGTTPAAIDACL
AVADESGVQVNIHTDTLNEMGFVEDTLAAIKGRSIHAYHTEGAGGGHAPDIITVASHPNVLPSSTNPTRPHTVNTLDEHL
DMLMVCHHLNPAVPEDLSFAESRIRPSTMAAEDLLHDIGAISMIGSDSQAMGRIGEVVIRTWQTAHVMKRRRGALPGDGA
ADNNRARRYVAKYTICPAVAHGLDHEVGSVEVGKLADLVLWEPAFFGVRPHVVLKGGMIAWAAMGDANASIPTPQPVLPR
PMFGAAPAAAAATSVHFVSQQAVDDGLAGRLAVSRRLVAVRNVRGVGKAQMPLNDTLPEIEVDPDTFTVRIDGDVWQEDP
AVDLPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 1e-157 61
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 1e-157 61
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-148 56
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-148 56
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-148 56
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-148 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MycrhN_4835 YP_005002531.1 urease subunit alpha VFG0270 Protein 4e-134 55