Gene Information

Name : MycrhN_4642 (MycrhN_4642)
Accession : YP_005002343.1
Strain : Mycobacterium rhodesiae NBB3
Genome accession: NC_016604
Putative virulence/resistance : Unknown
Product : lysyl-tRNA synthetase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4659431 - 4662763 bp
Length : 3333 bp
Strand : -
Note : PFAM: Uncharacterized conserved protein (DUF2156); tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial

DNA sequence :
ATGACCGTCACTAGTCCGCCCGGCTCAGCGAGCACTGCAAAGACGCGACGCTCTTCCGCGTTCAGGTGGGTGCCCGCCGC
GGCCGGCTGGACTGTCGGCATCATCGCCACGCTGTCGCTGTTCGCCAGTGTGTCGCCGTTCTTCCGGTCACTGATCAAGG
TGCCGCGCGAATTCGTCAACGACTACGTCTTCAACTTCCCCGACACCAGCTTCGCGTGGGCGTTCGTGCTGGTGCTGCTG
GCCGCGGCGCTGGCCGCCCGCAAGAGCATCGCGTGGTGGATCCTCGTCGGATACATGATCGCGGCGCTCGGCTGGAACGT
CGGCGACCTCCTCTCCGGCGACGAATCGTGGTTGGAGGAAAGCGGCGAGGTCATCGGGCTCGCGTTCCACGTCGCAGCCA
TCGCGTTCCTCGTGCTGGCTCGCAAGGAATTCTGGGCCAAGGTGCGCCGCGGCGCGCTGATCAAAGCGGCGGCAACGCTT
GTCGCCGGCTTGGTCGTCGGCACCCTGATCGGATGGGGACTGCTCGAACTCTTCCCCGGAAGTCTGGCCCGCGAGGACCG
CTTCTTCTACGCGCTGAACCGCGTCGGGGCGTTCGCCGGCGCCAGCGCAGACGCATTCACCGGCCATCCGCACGTCATCG
TCAACGCGCTACTTGGTCTGTTCGGCGCCCTGGCGCTGATGGTGGCTGCGATCGTGCTGTTCCAGTCTCAACATGCGGAG
AACGCGCTCACCGGTGAGGACGAGTCGGCGATCCGTGGACTGCTCGAGTTGTACGGCAAGAACGACTCGTTGGGCTACTT
CGCGACGCGCCGCGATAAGTCGGTGGTCTTCGCACCCAACGGCCGAGCCGCCGTCACCTATCGCGTCGAGGTCGGCGTCT
GCCTCGCCAGCGGGGATCCCGTCGGCGATCCCAAGGCCTGGCCGCAGGCGATCGAGGCGTGGCTGGCGCTGTGCGGCGAC
TACGGCTGGGCACCGGGTGTGATGGGTGCGAGTTCGGCTGGCGCCGAGGCCTTCCGCGCGTCCGGTCTCAACGCCCTGCA
GCTCGGCGATGAGGCGATCCTGTATCCGGACAGTTTCCGGTTGTCGGGTCCGGATATGCGTGCGGTGCGCCAGGCGGTGA
CGCGCGCGCGGCGCGCAGGAGCATCGGTGCGGATTCGCAGACATCGCGATCTCGACGCCGACGAAATGGCCAGTGTGATC
GAGCGGGCCGATTCCTGGCGTGACACCGACGACGAACGCGGCTTCTCCATGGCGCTTGGTCGGCTCGGCGACCCGGCCGA
CGGCGACTGCCTACTGGTCGAGGCCGTGCAGCCCGGAGCCGGCGGCGATCAAGTCGTCGCGATGCTGTCGCTGGTGCCGT
GGGGGGCAAACGGTGCGTCGCTGGATCTGATGCGCCGATCGCCCCAATCCCCCAACGGCACCATCGAACTCATGGTCAGC
GAGCTGTGCATGCAGGCCGAAGGCATTGGCGTGACACGCGTTTCGCTGAACTTCGCGATGTTCCGCTCGGCGTTCGAACA
GGGCGCCCAGCTCGGCGCCGGACCGATTGCGCGGTTGTGGCGTGCGCTGCTGGTGTTCTTCTCGCGCTGGTGGCAGCTCG
AGACGCTGTACCGCTCGAACATGAAGTACCAGCCCGTGTGGGTGCCGCGCTATGCCTGCTACGAGGATGCGCGGCTGGTA
CCGCGCGTCGGGGTGGCGTCGGTGATCGCGGAAGGCTTCCTGGTGCTTCCGTTCTCCCGTCGGCACGAGCAGCCGCACAC
CGGCCACCACACCGCGGTGCCGCAGAGCATCGTCGACAGCGGTCTGCTGCACCACGACGGCACCGCCCCCGACGTCGACC
AGCTCCAGGTGGGTCTTGACGAGGAGGAGCAGTCCCGGCTGCCCGAACAGGTACGGGTCCGGATGGCCAAGCTCAAGGCG
TTGCAGGACAGCGGAATAGACGCCTATCCCGTCGGCGACGAACCCAGCCACACGATTCTCGCGGCGGTCGAATCCGAGGG
TGCGGGCACGCTGACCGTGGCCGGGCGGGTGCTGCGCATTCGCGACTACGGCGGCGTGCTGTTCGCGCAGATGCGCGACT
GGTCCGGGGAAGTCCAGCTGCTGCTTGACAATTCCCAACTCGAAGAGGGCACCACGGTCGACTTCACCCATGCCATCGAT
CTCGGCGACCTGATCCAGGTATCGGGGACGATGGGCTACAGCAAGAAGGGCACCCGGTCACTGATCGTGCTCAGCTGGCG
GTTGATCGGCAAGTGCCTACGCCCGCTGCCCGACAAGTGGAAAGGACTGACGGATCAGGAGGCCCGGGTACGTGCCCGTT
ACGTGGACCTTGCGATCAACACCGAGGCACGCGATCTGATCCGGGCGCGCAGCGGTGTGCTGCACGCGATCCGCGAAACC
CTGGTCGGCAAGGGGTTTTTGGAAGTCGAGACGCCGATCCTGCAGCAGATCCATGGCGGCGCCAACGCGAGGCCGTTCTT
GACTCACATCAACGCCTACGACCTCGATCTGTACCTGCGCATCGCTCCTGAGCTGTACCTCAAGCGACTGTGCGTCGGTG
GCGTCGAGCGGGTCTTCGAGCTGGGCCGCGCATTCCGCAACGAGGGCGTCGACTTCAGTCACAACCCCGAGTTCACGCTG
CTGGAGGCGTATCAGGCACACGCGGATTACAACGTGTGGATCGATGGGTGTCGCGAGCTGATCCAGAACGCCGCGCTGGC
AGCCAACGGAGCGCACGTGTTCATGCGTCCCCGAGACGACGGCACGCTGGAACCGGTCGACATCTCGGGCGTCTGGACGG
TCAAAACCGTGCACGACGCAATATCGGAAGCGCTCGGCGAACAGATCGGCCCCGAGACGGACCTCACGACGCTGCGCAGG
CTGTGTGACGGCGCGAAGATTCCGTATCTGACCCACTGGGACACCGGTGCGGTGGTGCTCGAACTGTATGAGCACCTGGT
CGAGGACCGCACCGAAGCGCCCACGTTCTACAAGGACTTCCCCACCTCGGTGTCACCGCTGACGCGGCCGCACCGCAGCA
TCCCCGGCGTCGCCGAGCGGTGGGACCTGGTGGCGTGGGGCGTCGAACTGGGAACCGCCTACAGCGAACTGACCGATCCG
GTCGAGCAGCGGCGACGACTGCAGGAGCAGTCGCTGCTGGCCGCGGGCGGCGACCCTGAGGCGATGGAACTCGACGAGGA
CTTTCTGCAGGCCATGGAGTACGCCATGCCGCCGACGGGTGGACTCGGAATGGGTGTGGACCGCGTCGTGATGCTGATCA
CCGGCCGCAGCATCCGCGAGACGCTGCCCTTCCCGCTGGCCAAACCTCGTTGA

Protein sequence :
MTVTSPPGSASTAKTRRSSAFRWVPAAAGWTVGIIATLSLFASVSPFFRSLIKVPREFVNDYVFNFPDTSFAWAFVLVLL
AAALAARKSIAWWILVGYMIAALGWNVGDLLSGDESWLEESGEVIGLAFHVAAIAFLVLARKEFWAKVRRGALIKAAATL
VAGLVVGTLIGWGLLELFPGSLAREDRFFYALNRVGAFAGASADAFTGHPHVIVNALLGLFGALALMVAAIVLFQSQHAE
NALTGEDESAIRGLLELYGKNDSLGYFATRRDKSVVFAPNGRAAVTYRVEVGVCLASGDPVGDPKAWPQAIEAWLALCGD
YGWAPGVMGASSAGAEAFRASGLNALQLGDEAILYPDSFRLSGPDMRAVRQAVTRARRAGASVRIRRHRDLDADEMASVI
ERADSWRDTDDERGFSMALGRLGDPADGDCLLVEAVQPGAGGDQVVAMLSLVPWGANGASLDLMRRSPQSPNGTIELMVS
ELCMQAEGIGVTRVSLNFAMFRSAFEQGAQLGAGPIARLWRALLVFFSRWWQLETLYRSNMKYQPVWVPRYACYEDARLV
PRVGVASVIAEGFLVLPFSRRHEQPHTGHHTAVPQSIVDSGLLHHDGTAPDVDQLQVGLDEEEQSRLPEQVRVRMAKLKA
LQDSGIDAYPVGDEPSHTILAAVESEGAGTLTVAGRVLRIRDYGGVLFAQMRDWSGEVQLLLDNSQLEEGTTVDFTHAID
LGDLIQVSGTMGYSKKGTRSLIVLSWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAINTEARDLIRARSGVLHAIRET
LVGKGFLEVETPILQQIHGGANARPFLTHINAYDLDLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTL
LEAYQAHADYNVWIDGCRELIQNAALAANGAHVFMRPRDDGTLEPVDISGVWTVKTVHDAISEALGEQIGPETDLTTLRR
LCDGAKIPYLTHWDTGAVVLELYEHLVEDRTEAPTFYKDFPTSVSPLTRPHRSIPGVAERWDLVAWGVELGTAYSELTDP
VEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lysS1 YP_005684273.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 4e-154 44
lysX YP_003784331.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 4e-154 44
lysS1 YP_005686365.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 4e-154 44
lysS1 YP_005682181.1 lysyl-tRNA synthetase Not tested PiCp 7 Protein 1e-153 44