Gene Information

Name : MycrhN_4579 (MycrhN_4579)
Accession : YP_005002283.1
Strain : Mycobacterium rhodesiae NBB3
Genome accession: NC_016604
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4591923 - 4593353 bp
Length : 1431 bp
Strand : +
Note : PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase

DNA sequence :
ATGCTCGCAGGCGTGAATAGACGCGGAAAGATCGTCTGCACCCTGGGCCCGGCCACCGCTACCGAAGACGCTGTGAAGGC
ACTGGTCGAGGCCGGAATGGACGTCGCGCGGCTCAACTTCAGCCACGGCGAGTACTCCGAACACGAAGCCAATTACAAAC
GCGTTCGCGCCGCATCCGACGCCACCGGACGCGCCGTCGGCATTCTCGCCGATCTGCAAGGCCCCAAGATCCGGCTGGGC
CGGTTCGCCGACGGGCCCACCGTCTGGGCCGACGGTGAGACAGTGCGAATCACGGTCGACGATTGCGAGGGCACTCACGA
CCGGGTGTCGACGACCTACAAGAGGCTCGCCGAGGACGCCACGGTCGGGGACCGCGTACTCGTCGACGACGGAAACGTCG
GTCTCGTCGTCGAAGAGATCGACGGCAACGACGTGGTGTGCACGGTCACCGAGGGCGGTCCGGTCAGCAACAACAAAGGG
ATGTCGCTACCGGGCATGAACGTGTCGGCTCCGGCCCTGTCGGAGAAGGACATCGAGGACCTCGAGTTCGCACTGCAGGT
CGGCGTCGATCTGGTCGCGCTGTCTTTCGTGCGCTCACCCGCCGACATCGAACTCGTGCACGAGATCATGGATCGCGTGG
GCAGGCGGGTGCCCGTCATCGCCAAACTCGAGAAGCCCGAAGCCATCGACAATCTCGAGGCGATCGTGCTCGCATTCGAC
GCGATCATGGTCGCCCGCGGCGACCTCGGTGTCGAGCTGCCGCTCGAAGAGGTCCCGCTGGTGCAGAAGCGGGCCATCCA
AATGGCAAGGGAGAACGCCAAACCCGTCATCGTCGCGACCCAGATGCTCGAGTCGATGATCGAGAACTCCAGGCCCACCC
GCGCCGAGGCGTCCGACGTGGCCAACGCGGTGCTCGACGGTGCGGACGCCGTGATGCTCTCGGGTGAGACCTCCGTGGGC
AAGTATCCGCTGGAGGCCGTCAAGACGATGGCCAGGATCGTGCGTGCGGTCGAAGAGAACTCGGTCGTCGTTCCGCCGCT
GACCCACGTACCCCGCACCAAGCGCGGCGTCATCTCGTATGCCGCCCGCGACATCGGCGAGCGGCTGGACGCCAAGGCGC
TGGTGGCCTACACGCAGTCCGGCGACACCGTCCGCCGGCTGGCGCGCCTGCACACACCGCTGCCGCTGCTCGCGTTCACG
TCGCTTCCCGAGGTCCGCAGTCAGCTCGCGCTGAGCTGGGGCACCGAGACATTCATCGTGCCTCACATTCAGACCACCGA
CGGAATGATCAAGCAGGTCGACAAGTCGCTGCTCGAACTCGGCCGCTACAAGCGCGGCGATCTGGTGGTCATCATCGCAG
GCGCTCCGCCCGGCACAGTAGGCTCCACCAATCTGATCCACGTACACCGGATCGGGGAGGACGACGTTTAA

Protein sequence :
MLAGVNRRGKIVCTLGPATATEDAVKALVEAGMDVARLNFSHGEYSEHEANYKRVRAASDATGRAVGILADLQGPKIRLG
RFADGPTVWADGETVRITVDDCEGTHDRVSTTYKRLAEDATVGDRVLVDDGNVGLVVEEIDGNDVVCTVTEGGPVSNNKG
MSLPGMNVSAPALSEKDIEDLEFALQVGVDLVALSFVRSPADIELVHEIMDRVGRRVPVIAKLEKPEAIDNLEAIVLAFD
AIMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLESMIENSRPTRAEASDVANAVLDGADAVMLSGETSVG
KYPLEAVKTMARIVRAVEENSVVVPPLTHVPRTKRGVISYAARDIGERLDAKALVAYTQSGDTVRRLARLHTPLPLLAFT
SLPEVRSQLALSWGTETFIVPHIQTTDGMIKQVDKSLLELGRYKRGDLVVIIAGAPPGTVGSTNLIHVHRIGEDDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-67 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-66 42
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-66 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-67 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MycrhN_4579 YP_005002283.1 pyruvate kinase VFG0479 Protein 3e-67 42