Gene Information

Name : MycrhN_4319 (MycrhN_4319)
Accession : YP_005002034.1
Strain : Mycobacterium rhodesiae NBB3
Genome accession: NC_016604
Putative virulence/resistance : Virulence
Product : peptide arylation enzyme
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4325885 - 4327537 bp
Length : 1653 bp
Strand : -
Note : PFAM: AMP-binding enzyme; TIGRFAM: 2,3-dihydroxybenzoate-AMP ligase

DNA sequence :
ATGAGCACCGGTTTAGACCCCAAGCAGAGCGATCTGACAGCGGGGTTCGTCCCGTTCCCTCCCGATCGGGCGGAGGAATA
CCGGCGGGCCGGTTATTGGACCGGTCGACCGCTGGACTCGATCCTGTCCGGCGCGGCTGCGCAGTGGCCGGACCGCACCG
CGGTGGTCGACCCGGACGTCAGCTACACCTTCGCCGAACTCGACACCCACGCTGATCGGATCGCCGCCGCGTTGACGGAT
CGTGGCATCGCCGCCGGCGACCGGGTGCTGTTGCAGCTGCCCAACTCGGTTCAGTTCGCGGTCGCGCTGTTCGGCCTGCT
GCGTGCGGGCGCGGTCCCGGTGATGTGCCTGCCGGGTCATCGTTACGCCGAACTGAGTCATTTCGCCGACGTCAGCGGTG
CGGTCGCCCTGGTCGTTCCCGATAAGGTCGCCGGCTTCGACTATCGCGACCTGGCGCAGGGTCTCCTGAACGACAATCCG
CGGCTGACCCACGTGTTCGTCGACGGCGACCCTGGTCCGTTCCAATCCTGGTCGCAGCTGGCCGATTTCGACGGACCGAT
CCGCAATCGGGCGTCGTTCGACCCCGGGGCCCCGGCGCTGCTGCTGGTATCCGGCGGCACCACCGGGCTGCCGAAGCTGA
TCGCCCGTACCCACGACGACTACGTGTACAACGCCACGGCGTGCGCACAGGCCTGCGAGATGACCGGCGATGACGTGTAT
CTGGTCGCCCTACCCGCCGGTCACAACTTCCCACTCGGCTGCCCTGGGCTGCTCGGCTCCATGACCGTCGGCGCCACAAC
GGTGTTCACCTCCGACCCGAGCCCCGAGTCGGCGTTCGCGTTGATCGACCGGCACAAGGTCACCGTCACCGGACTCGTGA
ACGCACTCGCCAAGGTGTGGACGCAAGCCTGTGAATGGGAACCGGTGCTCCCGACATCCCTTCGTCTGGTTCAGGTCGGC
GGGTCGCGGATGACCCCCGAGGAGGCCCGCTACATCCTCGACGGGCTGACCCCCGGACTGTCACAGATCTTCGGAATGGC
CGAAGGCATGCTGAATTTCACCCGACTCGGCGATCCTATCGATGTCGTGGTCAACACCCAGGGCAGGCCAATGTCCCCGC
ACGACGAGATGCGGGTGGTCGACGACGCGGGTGCGGACGTGGCGCCCGGTGAGGAGGGCGAGCTACTGGTGCGTGGGCCC
TACACGCTCAACGGCTACTACCGCGCCGACGAGGCGAACGCGCGGTCGTTCAGCCCCGACGGCTTCTACCGCACCGGCGA
TCGCGTCCGCATCTTCGCCGGCGGCCCGCGCGCCGGCTACGTCGAGGTCACCGGCCGCATCAAGGACGTCATCCACCGCG
GCGGTGAGACGGTCTCGGCCTCCGATCTGGAGGAGCACCTGCTCGCGCATCCGGCGATCTACGCGGCGGCCGCCGTTGCG
CTGCCCGATGAATATCTGGGCGAGAAGATCTGCGCCGCAGTGGTCTTCAGCGGGACGACGATCACCCTCGCCGAGCTGAA
CCAGTTCCTCGACGAGCGAGGGGTGTCGGCCCATTCACGACCCGACGTGCTCGCCCCGATGTCCACCCTGCCCAAGACCG
CGGTCGGCAAGGTCGACAAGAAGAAGGTCGTCGCGCAGCTCGCAGCGCCCTGA

Protein sequence :
MSTGLDPKQSDLTAGFVPFPPDRAEEYRRAGYWTGRPLDSILSGAAAQWPDRTAVVDPDVSYTFAELDTHADRIAAALTD
RGIAAGDRVLLQLPNSVQFAVALFGLLRAGAVPVMCLPGHRYAELSHFADVSGAVALVVPDKVAGFDYRDLAQGLLNDNP
RLTHVFVDGDPGPFQSWSQLADFDGPIRNRASFDPGAPALLLVSGGTTGLPKLIARTHDDYVYNATACAQACEMTGDDVY
LVALPAGHNFPLGCPGLLGSMTVGATTVFTSDPSPESAFALIDRHKVTVTGLVNALAKVWTQACEWEPVLPTSLRLVQVG
GSRMTPEEARYILDGLTPGLSQIFGMAEGMLNFTRLGDPIDVVVNTQGRPMSPHDEMRVVDDAGADVAPGEEGELLVRGP
YTLNGYYRADEANARSFSPDGFYRTGDRVRIFAGGPRAGYVEVTGRIKDVIHRGGETVSASDLEEHLLAHPAIYAAAAVA
LPDEYLGEKICAAVVFSGTTITLAELNQFLDERGVSAHSRPDVLAPMSTLPKTAVGKVDKKKVVAQLAAP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 6e-91 43
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 6e-91 43
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 6e-91 43
ybtE CAA21394.1 - Virulence HPI Protein 6e-91 43
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 4e-91 43
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 6e-91 43
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-89 42
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 1e-89 42
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 7e-91 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MycrhN_4319 YP_005002034.1 peptide arylation enzyme VFG1817 Protein 9e-164 67
MycrhN_4319 YP_005002034.1 peptide arylation enzyme VFG0168 Protein 4e-88 42