Gene Information

Name : MycrhN_3011 (MycrhN_3011)
Accession : YP_005000767.1
Strain : Mycobacterium rhodesiae NBB3
Genome accession: NC_016604
Putative virulence/resistance : Virulence
Product : NAD-dependent aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3014185 - 3015762 bp
Length : 1578 bp
Strand : +
Note : PFAM: Aldehyde dehydrogenase family

DNA sequence :
ATGTCGGTGCTGGTGGATCGGCAGTCGTTGACGACTGAGTCTGGGAGCGAGGGGTTTGTCATGGTGTTTGCACGGCCGGG
TGCTGAGGGCAGTGTTGTTGATTTCGCTGGCCGGTATGAGAATTTTATTGGCGGGCAGTGGGTCGCCCCGGTCGATGGGG
CGTATTTCGATAATCCCTCCCCGGTGACCGGTGAGGTGTTCACACAGGTGGCGCGGTCGTCGGCCGCCGATGTGGAGTTG
GCGTTGGATGCCGCGCACGCGGCGGCGGGCAAGTGGGGGGCGACGTCGCCGGCGGAGCGCTCGAACCTGTTACTGAAGGT
CGCCGACCGTATCGAGGAGCATCTGGAATCGTTGGCGGTGGCCGAGACGTGGGATAACGGCAAGCCGGTGCGGGAAACCC
TGGCCGCGGATCTGCCGTTGGCGGTGGATCATCTCCGATATTTCGCTGGGGCGTTGCGGGCTCAGGAAGGGTCGATCGCC
CAGATCAACGAGGACACGATCGCTTATCACTTCCAGGAGCCGTTGGGGGTGGTGGCCCAGATCATTCCGTGGAACTTCCC
GATCTTGATGGCGATCTGGAAGGTGGCGCCGGCGTTGGCGGCCGGTAACTGTGTGATCCTCAAGCCCGCTGAGCAGACCC
CGGTGTCGATCCTGAAGGTCATCGAGGTGATCGCCGATCTGCTGCCGCCCGGGGTTTTGAATGTAGTCAACGGGTTCGGG
GTGGAGGCGGGCAAGCCGCTGGCCTCCAGCGCGCGGGTGGCCAAGGTGGCGTTCACCGGGGAGACCACCACGGGGCGGCT
GATCATGCAGTACGCCAGTGAGAACATCATCCCGGTGACCTTGGAGCTGGGCGGTAAGAGCCCGAACATCTTCTTGCCCG
ATGTCGCCGCGGCCGATGACGAGTTCCTGGACAAGGCGGTCGAGGGTTTTGTGATGTTTGCCCTCAATCAGGGTGAGGTG
TGCACGTGTCCGTCGCGGGCGTTGATCCACTCGTCGATTTATGACGAGTTCATCAGCCGCTGTGTGGCGCGCACCGAGGC
CATCGTCAGCGGGGATCCGCTGGATCCGGCCACCATGATCGGCGCGCAGGCCAGCAACGACCAGTTCGAGAAGATCATGT
CCTACATCGACATCGGCCGCAAAGAGGGCGCGCAGGTACTCACCGGTGGCGGGGCGCGCAAGGTGCCCGAATATCCGGGT
GGACACTACGTCGAGCCGACCATCTTCAAGGGCACCAACGATATGCGGATCTTCCAGGAAGAGATCTTCGGCCCGGTGGT
GTCGGTGACGACGTTCGATTCGGTCGATGAGGCGCTCAAACTGGCCAACGACACCCTCTACGGCCTGGGGGCGGGGGTGT
GGACGCGTGATGCCAACACCGCCTACCGGCTGGGCCGGGGCATCAAGGCCGGGCGGGTGTGGACCAACTGCTACCACGAC
TACCCCGCCCATGCCGCGTTCGGTGGCTACAAGAAATCCGGCATCGGACGCGAATGCCACAAAATGATGCTCGACCACTA
TCAGCAAACCAAGAACCTGTTGGTCAGCTACTCGCCGACCAAACAAGGGTTCTTCTGA

Protein sequence :
MSVLVDRQSLTTESGSEGFVMVFARPGAEGSVVDFAGRYENFIGGQWVAPVDGAYFDNPSPVTGEVFTQVARSSAADVEL
ALDAAHAAAGKWGATSPAERSNLLLKVADRIEEHLESLAVAETWDNGKPVRETLAADLPLAVDHLRYFAGALRAQEGSIA
QINEDTIAYHFQEPLGVVAQIIPWNFPILMAIWKVAPALAAGNCVILKPAEQTPVSILKVIEVIADLLPPGVLNVVNGFG
VEAGKPLASSARVAKVAFTGETTTGRLIMQYASENIIPVTLELGGKSPNIFLPDVAAADDEFLDKAVEGFVMFALNQGEV
CTCPSRALIHSSIYDEFISRCVARTEAIVSGDPLDPATMIGAQASNDQFEKIMSYIDIGRKEGAQVLTGGGARKVPEYPG
GHYVEPTIFKGTNDMRIFQEEIFGPVVSVTTFDSVDEALKLANDTLYGLGAGVWTRDANTAYRLGRGIKAGRVWTNCYHD
YPAHAAFGGYKKSGIGRECHKMMLDHYQQTKNLLVSYSPTKQGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 6e-144 61
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 6e-153 61
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 6e-153 61
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 6e-153 61
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 8e-153 61
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-73 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MycrhN_3011 YP_005000767.1 NAD-dependent aldehyde dehydrogenase VFG0082 Protein 3e-144 61