Gene Information

Name : MycrhN_2492 (MycrhN_2492)
Accession : YP_005000295.1
Strain : Mycobacterium rhodesiae NBB3
Genome accession: NC_016604
Putative virulence/resistance : Resistance
Product : copper/silver-translocating P-type ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2516038 - 2518065 bp
Length : 2028 bp
Strand : +
Note : PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC

DNA sequence : 
GTGAGTCACGAGGTCCACGGCTCGCACGGCGGCCACGGTGACCATGGCGATCACGTCGCAGTGTTCCGGCGCATGTTCTG
GGTGATGCTCCTGCTGGCCGTCCCGACCGTCGCGCTCTCGCCGATGTTCGCGATGATCCTCGGCTACGCCCTTCCGGAGT
TCCCCGGTGCGCAATGGGTGTCGCCGGTATTGGGAACGGTGATGTACGCCTGGGGCGGCCGGCCGTTCCTGACCGGCGCG
GTCGGTGAGATCCGTTCGCGCGCACCGGGAATGATGCTGCTGATCGGGCTTGCGATCACGGTGGCCTTCGTATCGTCGTG
GGGCGCCAGCCTGGGCCTGCTGCACCACCAACTCGACTTCTGGTGGGAGCTGGCGCTGCTGATCGTGATCATGCTGCTCG
GCCACTGGATCGAGATGCGGTCGCTGGCACAGACCACGTCGGCGTTGGACTCGCTGGCCGCACTGCTGCCCGATGAGGCG
GAGCGCGTCGTAGGTGTGAGCACGGAGACGGTACCGCCGTCCGAACTGCGGGTGGGCGACGTGGTGATCGTGCGACCCGG
GGGCAGTGTTCCCGCTGACGGCGAGATCGTCGACGGAACGGCGGATGTCGACGAGTCGATGGTCACCGGCGAGTCGCGTC
CGGTGCGCCGCGGTGTCGGCGACCAGGTGGTCGCGGGCACCGTCGCCACCGACTCCGGTCTGCGGGTGAGGGTGGCCGCC
ATCGGCGACGACACCACCCTGGCAGGCATTCAGCGGCTGGTGACCGAGGCGCAGAACTCGTCGTCACGGGCTCAGCGTCT
CGCGGACAAGGCGGCCGGCTGGCTGTTCTGGTTCGCGCTGGGCGCCGCGATCGTCACCGCCGTCGTGTGGAGCGTTCTCG
GCCAGCCTGATCAGGCCGTGGTGCGCACCATCACGGTCCTGGTGATCGCCTGCCCCCACGCTTTGGGCCTGGCGATTCCG
CTGGTGGTGTCCATCGCCACCGAACGCGCGGCCCGCGGCGGCGTGCTGATCAAGGACCGGCTCGCGCTGGAGAGCATGCG
CACCGTCGGCGTGGTGTTGTTCGACAAGACCGGGACGTTGACCAAGGGCGAGCCGACCGTCACCGCGGTCGCGACCACAG
ACCGGTCCGAGGACGACCTGTTGGCGTTGGCGGCAGCGGCGGAAACCGACTCGGAGCATCCGCTGGCTCGCGCGATCGTC
GAGGCCGCCCGCACGCGCGGGCTGTCGATTCCACCGTCGTCGGACTTCAGCTCCTCGCCCGCGGTCGGTGTCGAGGCGGC
GGTGGACGGACATCGGGTGCGGGTCGGCGGGCCGCGCCTGCTGGAGGAGGCGGGCCAGGACGAGCTTTCCGACGTGCAGT
CATGGCGCGCGGAAGGCGCCATAGTGCTGCACGTGCTGGTCGACGGCGTCGTGGCCGGGGCGCTCAAGCTCGCCGACGAG
GTGCGCCCCGAGTCCCGCGAGACCGTCGACGCCCTGCACAAGCTGGACATCGAGGTGGTGATGATCACAGGCGACGCCGA
GTCGGTGGCGCGGTCGGTGGCCGACGATCTCGGCATCGAGCGGGTGTACGCCGGCGTTCGTCCTGGTGACAAGGCGGCGA
AGGTCGGTGAGCTTCAACACGAAGGACTCGGCCGGGGGCGGGGAGTCGCGATGGTGGGCGACGGCGTCAACGACGCGCCC
GCGCTGGCACAAGCGGACGTCGGGATCGCGATCGGCGCGGGTACCGATGTGGCCATCGCGTCGGCAGGCGTGATCCTCGC
GAGTTCTGATCCACGGTCGGTGCTCTCGGTGATCGTGTTGTCCCGGGCGACCTACCGGAAGATGAAGCAAAACCTCTGGT
GGGCAGCGGGATACAACCTGATCTCGGTTCCGCTTGCGGCAGGTGTGCTGGCACCGATCGGCTTTGTGCTGCCGATGTCG
GTGGGTGCGATCTTGATGTCGGTGTCGACGGTTGTGGTCGCCGCCAACGCCCAGCTGCTCCGCAGGCTGGACCTGACTCC
CGAGGCGAGTGTGCAGTCCATTCTCTAA

Protein sequence : 
MSHEVHGSHGGHGDHGDHVAVFRRMFWVMLLLAVPTVALSPMFAMILGYALPEFPGAQWVSPVLGTVMYAWGGRPFLTGA
VGEIRSRAPGMMLLIGLAITVAFVSSWGASLGLLHHQLDFWWELALLIVIMLLGHWIEMRSLAQTTSALDSLAALLPDEA
ERVVGVSTETVPPSELRVGDVVIVRPGGSVPADGEIVDGTADVDESMVTGESRPVRRGVGDQVVAGTVATDSGLRVRVAA
IGDDTTLAGIQRLVTEAQNSSSRAQRLADKAAGWLFWFALGAAIVTAVVWSVLGQPDQAVVRTITVLVIACPHALGLAIP
LVVSIATERAARGGVLIKDRLALESMRTVGVVLFDKTGTLTKGEPTVTAVATTDRSEDDLLALAAAAETDSEHPLARAIV
EAARTRGLSIPPSSDFSSSPAVGVEAAVDGHRVRVGGPRLLEEAGQDELSDVQSWRAEGAIVLHVLVDGVVAGALKLADE
VRPESRETVDALHKLDIEVVMITGDAESVARSVADDLGIERVYAGVRPGDKAAKVGELQHEGLGRGRGVAMVGDGVNDAP
ALAQADVGIAIGAGTDVAIASAGVILASSDPRSVLSVIVLSRATYRKMKQNLWWAAGYNLISVPLAAGVLAPIGFVLPMS
VGAILMSVSTVVVAANAQLLRRLDLTPEASVQSIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SH0105 YP_252020.1 hypothetical protein Not tested SCCmec Protein 4e-86 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MycrhN_2492 YP_005000295.1 copper/silver-translocating P-type ATPase BAC0629 Protein 4e-121 47
MycrhN_2492 YP_005000295.1 copper/silver-translocating P-type ATPase BAC0383 Protein 1e-108 44
MycrhN_2492 YP_005000295.1 copper/silver-translocating P-type ATPase BAC0079 Protein 2e-121 44
MycrhN_2492 YP_005000295.1 copper/silver-translocating P-type ATPase BAC0101 Protein 1e-75 43
MycrhN_2492 YP_005000295.1 copper/silver-translocating P-type ATPase BAC0102 Protein 6e-83 41