Gene Information

Name : MycrhN_2206 (MycrhN_2206)
Accession : YP_005000012.1
Strain : Mycobacterium rhodesiae NBB3
Genome accession: NC_016604
Putative virulence/resistance : Virulence
Product : chaperone ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2236362 - 2238905 bp
Length : 2544 bp
Strand : +
Note : PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); UvrB/uvrC motif

DNA sequence :
ATGTTCGAGAGATTCACCGACCGTGCCCGCAGGGTCGTCGTCCTGGCTCAAGAAGAGGCCCGGATGCTCAACCACAACTA
CATCGGAACCGAGCACATCCTTCTTGGGCTCATCCACGAGGGCGAGGGTGTGGCAGCCAAGTCGCTGGAGTCGCTCGGGA
TCTCGCTCGAGGGTGTGCGCAGCCAGGTCGAGGAGATCATCGGCCAGGGCCAGCAGGCCCCCTCCGGCCACATCCCCTTC
ACCCCCCGCGCCAAGAAGGTGCTGGAGTTGTCTCTGCGCGAGGCGCTGCAGCTCGGCCACAACTACATCGGCACCGAGCA
CATTCTGCTCGGCCTGATTCGCGAGGGCGAGGGCGTGGCCGCCCAGGTGCTCGTGAAGCTGGGCGCCGAGCTCACCCGCG
TGCGTCAGCAGGTCATCCAGCTGCTGAGCGGTTACCAGGGCAAAGAGACCGCGGAAGCCGGTACCGGGGGCCGCGGCGGA
GAGGCGGGCAACCCGTCGACGTCGCTGGTGCTCGATCAGTTCGGCCGTAACCTGACCGCCGCCGCCATGGAGGGCAAGCT
CGACCCGGTCATCGGCCGTGAGAAGGAAATCGAGCGTGTCATGCAGGTGCTGAGCCGCCGCACCAAGAACAACCCGGTGC
TGATCGGCGAGCCCGGCGTCGGCAAGACCGCCGTCGTCGAGGGCCTGGCACAAGCGATCGTGCACGGCGAGGTTCCCGAG
ACGCTGAAGGACAAGCAGCTTTACACGCTTGACCTCGGTTCGCTGGTGGCCGGTAGCCGCTACCGCGGTGACTTCGAGGA
GCGCCTCAAGAAGGTGCTCAAGGAGATCAACACCCGCGGCGACATCATCCTGTTCATCGACGAGCTGCACACGCTCGTGG
GTGCGGGCGCCGCCGAGGGCGCTATCGACGCCGCATCGATCCTCAAGCCCAAGCTGGCCCGCGGCGAGCTGCAGACGATC
GGTGCGACCACGCTCGACGAGTACCGCAAGTACATCGAGAAGGATGCCGCGCTGGAGCGGCGATTCCAGCCGGTGCAGGT
CGGTGAGCCGACGGTCGAGCACACCATCGAGATCCTCAAGGGCCTTCGCGATCGCTACGAGGCGCACCACCGCGTCTCGA
TCACCGATCCCGCGATCGTCGCGGCGGCCACCCTTGCCGACCGCTACATCAACGACCGGTTCCTGCCGGACAAGGCGATC
GACCTGATCGACGAGGCCGGCGCGCGGATGCGCATCCGCCGGATGACCGCTCCGCCGGACCTGCGCGAATTCGACGAGAA
GATCGCCGACGCACGTCGGGAGAAGGAATCCGCGATCGATGCGCAGGACTTCGAGAAGGCGGCCAGCCTGCGCGACAAGG
AGAAGCAACTCGTCGCACAGCGTGCCGAGCGTGAGAAGCAGTGGCGCTCAGGGGATCTCGACGTCGTTGCCGAGGTCGAC
GACGAGCAGATCGCCGAGGTGCTCGGCAACTGGACCGGTATCCCCGTGTTCAAGCTGACCGAGGAGGAGACCACTCGGCT
GCTGCGCATGGAGGAGGAGCTGCACAAGCGGATCATCGGCCAGGAGGACGCCGTCAAGGCGGTCTCCAAGGCGATCAGGC
GCACCCGCGCCGGCCTGAAGGATCCCAAGCGGCCGTCGGGCTCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACC
GAGCTGTCCAAGGCGCTGGCGAACTTCCTGTTCGGCGACGACGACGCACTCATCCAGATCGACATGGGCGAGTTCCACGA
CCGCTTCACCGCCTCGCGGCTGTTCGGCGCCCCTCCGGGCTACGTCGGTTACGAGGAAGGTGGTCAGCTCACCGAGAAGG
TGCGTCGCAAGCCGTTCAGCGTCGTGCTGTTCGACGAGATCGAGAAGGCTCACCAGGAGATCTACAACAGCCTCCTGCAG
GTTCTCGAAGACGGCCGCCTGACCGATGGTCAGGGTCGCACGGTCGACTTCAAGAACACGGTCTTGATCTTCACGTCGAA
CCTGGGCACCTCGGACATATCGAAGGCGGTCGGACTCGGCTTCACCCAGGGTGGCGGCGAGAACAACTACGAGCGGATGA
AGCAGAAGGTCAACGACGAGCTGAAGAAGCACTTCCGGCCCGAGTTCCTCAACCGCATCGACGACATCATCGTCTTCCAC
CAGCTGACTCGCGACGAGATCATCCAAATGGTCGACCTGATGATCGGCCGGGTGGAGAAGCAGCTCAAGGCCAAGGACAT
GGCCATGGAGCTCACCGACAAGGCCAAGTCGCTATTGGCCAAGCGCGGATTCGACCCCGTGCTCGGCGCGCGGCCGCTGC
GTCGCACCATCCAGCGCGAGATCGAGGACCAACTCTCCGAGAAGATCCTCTTCGAGGAAGTCGGTCCCGGCCAGCTCGTC
ACCGTCGACGTCGACAACTGGGATGGCGAGGGTGCGGGCGAGGACGCGGTCTTCACCTTCACCGGCACCAAGAAGCCGGC
CAAGATCGACGAGCCGGCGGACCTGGCTCAGGCCGGTGCCGCAGGAGCAACGAGCGTCGAATAA

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKETAEAGTGGRGG
EAGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPE
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDPAIVAAATLADRYINDRFLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASLRDKEKQLVAQRAEREKQWRSGDLDVVAEVD
DEQIAEVLGNWTGIPVFKLTEEETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQ
VLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKAVGLGFTQGGGENNYERMKQKVNDELKKHFRPEFLNRIDDIIVFH
QLTRDEIIQMVDLMIGRVEKQLKAKDMAMELTDKAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQLV
TVDVDNWDGEGAGEDAVFTFTGTKKPAKIDEPADLAQAGAAGATSVE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 82

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MycrhN_2206 YP_005000012.1 chaperone ATPase VFG0079 Protein 0.0 61
MycrhN_2206 YP_005000012.1 chaperone ATPase VFG0080 Protein 2e-144 51