Gene Information

Name : MycrhN_1185 (MycrhN_1185)
Accession : YP_004999023.1
Strain : Mycobacterium rhodesiae NBB3
Genome accession: NC_016604
Putative virulence/resistance : Virulence
Product : NAD-dependent aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1200782 - 1202305 bp
Length : 1524 bp
Strand : -
Note : PFAM: Aldehyde dehydrogenase family

DNA sequence :
ATGACTGTCTATGCACGCCCCGGTTCCGCTGACGCCCTGATGTCGTACGAATCGCGGTACGGCAACTTCATCGGCGGGGA
ATGGGTGCCGCCCGCGGGCGGTGAGTATTTCGAGAACCTCACACCGGTGACCGGGCAGCCCTTCTGTGAGATTCCCCGGT
CGACCGACGCCGACATCGAAAAGGCGCTCGACGCCGCGCACGGTGCGGCCACCGCATGGGGCAAGACCGCGGCGGGCGAA
CGTGCGAACATCCTCAACAAGATCGCGGACCGCATCGAGGCCAATCTCGAATCACTGGCGCTGGCCGAGGCGTGGGACAA
CGGCAAGCCGATCCGCGAGACGCTCAATGCCGATCTTCCGCTGGCCGTCGACCACTTCCGCTACTTCGCCGGCGCCATCC
GGGCCCAGGAGGGCTCGCTGAGCCAGATCGACGACGACACCGTCGCGTATCACTTCCACGAACCGCTCGGTGTGGTCGGC
CAGATCATCCCGTGGAACTTCCCGATCCTGATGGCCACGTGGAAGCTGGCGCCCGCACTCGCTGCGGGTAACGCGGTCGT
GCTCAAACCGGCGGAGCAGACGCCGGCGTCGATCTTGTACCTGATGAGCCTGATCGGTGACCTGCTGCCTGCTGGAGTCC
TCAACGTCGTCAACGGATTCGGTTTCGAGGCGGGCAAGCCGCTGGCGTCGAGCAACCGCATCGCCAAGATCGCGTTCACC
GGTGAGACCACGACCGGCCGGCTGATCATGCAGTACGCGTCGCAGAACCTGATCCCCGTCACGCTCGAACTGGGCGGCAA
GAGTCCCAACATCTTCTTCAGCGACGTGATGGCAGCGGCCGACGACTACCAGGACAAGGCGCTGGAAGGGTTCACGATGT
TCGCCCTCAACCAAGGCGAGGTGTGCACCTGCCCGTCGCGCAGCCTGATCCAGGCCGACATCTACGACGAGTTCCTCGAA
CTCGCAGCGATTCGTACCAAGGCTGTGCGCCAGGGTGATCCGCTGGACACCGAGACGATGATCGGATCGCAGGCGTCCAA
CGATCAGCTCGAGAAGGTGTTGTCCTACATCGAGGTCGGCAAAGATGAAGGGGCGAGGGTCATTGCGGGCGGAGAGCGCG
CACAGCTCGGCGGCGACCTCAACGGCGGCTACTACGTCCAGCCCACGATCTTCGAGGGCAACAACAAGATGCGCATCTTC
CAGGAGGAGATCTTCGGACCCGTCGTCGCGGTGACGTCGTTCTCCGACTACGACGACGCCATCGGCATGGCCAACGACAC
GCTGTACGGACTCGGTGCCGGGGTGTGGTCGCGCGACGGCAACGTCGCCTACCGAGCCGGCCGCGACATCAAGGCGGGCC
GAGTGTGGACCAACTGCTACCACGCCTATCCGGCACATGCGGCGTTCGGCGGTTACAAGCAGTCCGGAATCGGCCGCGAG
ACGCACAAGATGATGTTGGACCACTATCAGCAGACCAAGAACCTGCTGGTGTCGTACTCGAACAAGGCGCAAGGCTTCTT
CTGA

Protein sequence :
MTVYARPGSADALMSYESRYGNFIGGEWVPPAGGEYFENLTPVTGQPFCEIPRSTDADIEKALDAAHGAATAWGKTAAGE
RANILNKIADRIEANLESLALAEAWDNGKPIRETLNADLPLAVDHFRYFAGAIRAQEGSLSQIDDDTVAYHFHEPLGVVG
QIIPWNFPILMATWKLAPALAAGNAVVLKPAEQTPASILYLMSLIGDLLPAGVLNVVNGFGFEAGKPLASSNRIAKIAFT
GETTTGRLIMQYASQNLIPVTLELGGKSPNIFFSDVMAAADDYQDKALEGFTMFALNQGEVCTCPSRSLIQADIYDEFLE
LAAIRTKAVRQGDPLDTETMIGSQASNDQLEKVLSYIEVGKDEGARVIAGGERAQLGGDLNGGYYVQPTIFEGNNKMRIF
QEEIFGPVVAVTSFSDYDDAIGMANDTLYGLGAGVWSRDGNVAYRAGRDIKAGRVWTNCYHAYPAHAAFGGYKQSGIGRE
THKMMLDHYQQTKNLLVSYSNKAQGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-141 63
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-148 61
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-148 61
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-148 61
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 8e-148 61
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-68 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
MycrhN_1185 YP_004999023.1 NAD-dependent aldehyde dehydrogenase VFG0082 Protein 4e-142 63