Gene Information

Name : Oweho_2603 (Oweho_2603)
Accession : YP_004990216.1
Strain : Owenweeksia hongkongensis DSM 17368
Genome accession: NC_016599
Putative virulence/resistance : Virulence
Product : NAD-dependent aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2900013 - 2901455 bp
Length : 1443 bp
Strand : +
Note : PFAM: Aldehyde dehydrogenase family; TIGRFAM: 2-hydroxymuconic semialdehyde dehydrogenase

DNA sequence :
ATGAAAAAGATTTTAAACTACATAGATGGCGAACTTCTGGAACCAATTTCCGGCAAGTTTATGGACAATATTGATCCTTC
TCGTGGCCAGGTGTATTCCTTGATTCCTGAGTCGGATGGGGCGGATGTGCAGAAAGCTGTGGAGGCCGCGAAAAGAGCTT
TTCCAATTTGGAGCGCTATGTCAGCCAAAGAGCGTTCGGAGATTTTGCTTCGAGTGTCGCAAGGTATTTCTGATAGGCTA
GATGAATTGGCGGCAGCCGAAAGTTTAGATAATGGCAAGCCTTTAAAGCTGGCCACTTCGGTGGATATTCCCAGAGCCCG
TGATAACTTTTCATTTTTTGCGACAGCTATTTTGCATGATGAAGACCAGTTTCATAATATGGGTACTCGGGGTTTTAATT
ATACTCTTCGTCAACCGATTGGTGTGGTGGGCTGTATTTCCCCATGGAACTTGCCCCTTTACCTTTTTAGTTGGAAAATA
GCTCCGGCTTTAGCTGCTGGAAACTGCGTGGTGGCAAAGCCATCTGAGGTTACTCCGATGACGGCTTATTTACTTTCAGA
AATTTGCCGTGAGGCGGGAATGCCAGCCGGTGTATTAAATATTCTTCATGGGCTTGGGCCAGCGGTTGGTCAGGCTATTG
TGGAGCATCCAGAAATAAAGGCAATTTCATTTACAGGAGGTACCAAAACAGGTGAGCACTTGGCGCGTACAGCGGCTCCT
ATGTTTAAGAAGCTTTCTCTCGAATTGGGAGGTAAAAACCCCAATTTGATTTTTGCAGATTGTGATTTTGATAAAGCGGT
AAAAACTTCGGTCACTTCTTCCTTTGCCAATCAAGGGCAAATTTGCCTTTGCGGAAGCCGAATCTTTGTAGAGCGTAGCA
TTTACGATAAGTTTAAAAAAGCTTTTGTAGAGCGTGTAAAAGGACTAAAAGTTGGTCCACCGCAAGAAGAAACCAGCCGA
ATGGGAGCTGTGGTTTCTGAAGTACATATGAACAAAGTTTTGGATTACATCTCTCTTGCCGAGGAAGAAGGTGGAACAAT
TCTTACCGGAGGAAACCGTGTGAAATTGGATGGCGAATTTGCCGAAGGCTATTATATTGAACCAACGGTGATTGAAGGTT
TGGCTTACGATTGCCGCACCAATCAAGAAGAGATTTTTGGACCGGTAGTTACCATCACACCCTTTGATACCGAAGAGGAA
GCCTTGATGATGGCCAATTCTACGGAGTACGGTTTGGCCTGTACTGTGTGGACAGAAAATCTAAACCGTGCACACCGAGT
AGCGGCTCAAATGCAATCCGGAATTGTATGGATAAACTGCTGGTTGGTTCGCGATTTGAGAACCTTATTTGGAGGAATGA
AAAACAGTGGAGTAGGTCGCGAAGGCGGTTATGAAGCGCTGCACTTTTTTACGGAGGCAAAGAATGTTTGCTTAACATAT
TAG

Protein sequence :
MKKILNYIDGELLEPISGKFMDNIDPSRGQVYSLIPESDGADVQKAVEAAKRAFPIWSAMSAKERSEILLRVSQGISDRL
DELAAAESLDNGKPLKLATSVDIPRARDNFSFFATAILHDEDQFHNMGTRGFNYTLRQPIGVVGCISPWNLPLYLFSWKI
APALAAGNCVVAKPSEVTPMTAYLLSEICREAGMPAGVLNILHGLGPAVGQAIVEHPEIKAISFTGGTKTGEHLARTAAP
MFKKLSLELGGKNPNLIFADCDFDKAVKTSVTSSFANQGQICLCGSRIFVERSIYDKFKKAFVERVKGLKVGPPQEETSR
MGAVVSEVHMNKVLDYISLAEEEGGTILTGGNRVKLDGEFAEGYYIEPTVIEGLAYDCRTNQEEIFGPVVTITPFDTEEE
ALMMANSTEYGLACTVWTENLNRAHRVAAQMQSGIVWINCWLVRDLRTLFGGMKNSGVGREGGYEALHFFTEAKNVCLTY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 2e-91 44
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-80 42
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-82 42
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-82 42
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-82 42
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-82 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Oweho_2603 YP_004990216.1 NAD-dependent aldehyde dehydrogenase VFG0082 Protein 8e-81 42