Gene Information

Name : Oweho_2135 (Oweho_2135)
Accession : YP_004989754.1
Strain : Owenweeksia hongkongensis DSM 17368
Genome accession: NC_016599
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase/cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2386328 - 2387488 bp
Length : 1161 bp
Strand : -
Note : PFAM: Cys/Met metabolism PLP-dependent enzyme

DNA sequence :
ATGGCAGACGATAATTTGAAATTCAACACACTTACCATACACGGTGGCCAGCAGCCCGACAAGGCTTATGGCGCGGTGAT
GCCCCCTATTTACCAAACATCAACTTATGCTCAGGCAGCTCCAGGGGATCATCAGGGCTTTGAGTATTCTCGCTCTGGAA
ACCCTACCCGAAAAGCTTTGGAAGATAGCATTGCTTCCATAGAGGGTGGAAAGTTTGGTTTGGCTTTCGGCAGTGGGTTG
GCGGCTATTGATTGCGTTATCAAAACCCTAAAGCCAGGTGATGAGGTAATTTCTACCAATGATTTGTACGGAGGCACCTA
TCGTTTGTTTACCAAAATATTTGAGCCATTAGGCATCAAGTTTCATTTTGTGGATATGGACAATGCCGATAAAATTGGTG
ACTATGTAAATGAAAACACCAAGATTATTTGGGTGGAAACCCCTACCAACCCCATGATGAATATCATCGACATCAAAGCG
ATGAGCAAGGTGGCTAAAGCTGCCAATGCACTTTTGATAGTGGACAACACTTTTGCCACGCCTTACCTTCAACGCCCGCT
GGAAATGGGAGCCGATATTGTGATGCACAGTGCTACCAAATATTTGGGCGGCCACTCAGATGTGGTGTTGGGTTTACTTG
CCGTAAAAGATGAAGCTATTGCTGAAAAGTTGTATTTCATTCAAAATTCTTCCGGTGCCGTTTGCGGTCCCATGGATGCT
TTTTTGGTAGTTCGCGGAATAAAAACTTTGCACGTACGTATGCAGCGCCATTGCGAAAATGGAAAGGCCATTGCTCACTT
TTTGAAGGATCACCCTAAAGTGGAAAATGTGTACTGGCCAGGCTTTGAAAGTCATCCAAATCACAGTGTTGCCAAAGAGC
AAATGAAGGATTTTGGTGGAATGATTTCCTTTAGCATAAAGGGTGGGTCATTAGAGGATACGAGGAAAGTGATTTCTTCT
TTTAATGTGTTCACTTTGGCAGAATCCTTGGGGGGCGTAGAATCATTGGCCGGGCATCCTGCAAGTATGACGCATGCTTC
CATCCCAAAAGAAGAAAGAGAGAAGCTAGGAATTGTAGATTCGCTAATTCGCCTCAGCGTGGGTATTGAAGATATTGACG
ACCTTAAAGCCGACATTGATCAGGCATTAAATAAAATATAG

Protein sequence :
MADDNLKFNTLTIHGGQQPDKAYGAVMPPIYQTSTYAQAAPGDHQGFEYSRSGNPTRKALEDSIASIEGGKFGLAFGSGL
AAIDCVIKTLKPGDEVISTNDLYGGTYRLFTKIFEPLGIKFHFVDMDNADKIGDYVNENTKIIWVETPTNPMMNIIDIKA
MSKVAKAANALLIVDNTFATPYLQRPLEMGADIVMHSATKYLGGHSDVVLGLLAVKDEAIAEKLYFIQNSSGAVCGPMDA
FLVVRGIKTLHVRMQRHCENGKAIAHFLKDHPKVENVYWPGFESHPNHSVAKEQMKDFGGMISFSIKGGSLEDTRKVISS
FNVFTLAESLGGVESLAGHPASMTHASIPKEEREKLGIVDSLIRLSVGIEDIDDLKADIDQALNKI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-87 51
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-88 51
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-62 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Oweho_2135 YP_004989754.1 cystathionine beta-lyase/cystathionine gamma-synthase BAC0207 Protein 4e-75 45