Gene Information

Name : Oweho_1614 (Oweho_1614)
Accession : YP_004989248.1
Strain : Owenweeksia hongkongensis DSM 17368
Genome accession: NC_016599
Putative virulence/resistance : Virulence
Product : NAD-dependent aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1742158 - 1743684 bp
Length : 1527 bp
Strand : -
Note : PFAM: Aldehyde dehydrogenase family

DNA sequence :
ATGGAAGCAGCAACAGCATCATTTCCCTTTGTTGGGAAATCAGTTGAGTTTAAACCAAAATATGAGCACTTCATTGGAGG
TGAATGGGTAAAACCAAGCAATGGTGAATATTTTGAAAATATATCCCCAATAAATGGACAACCTTTTACTCAAGCAGCCC
GGGGTACCAAAGCAGATATTGAGTTAGCATTGGATGCAGCTCATAAAGCTTTTCCTTCATGGAGTAAGACTTCAGCGGCA
AGCCGATCTAATATGCTCAATAAAATAGCACAAGTAATAGAGGATAACTTAGAATATCTGGCCACTATAGAAACTATAGA
TAATGGAAAGGCTATTCGTGAATGTATGGCGGCAGATTTGCCTCTAGTGATAGATCACTTCCGCTACTTTGCCGGAGTTA
TTCGTGCTGATGAAAGCACTATTTCTGAGCATGATGAAAATACGGTGAGCATCGCTTTGCACGAACCATTGGGCGTTGTT
GGTCAAATTATTCCATGGAACTTCCCTCTATTAATGGCCACATGGAAAGTAGCTCCGGCATTAGCCGCAGGAAATTGCAT
AGTGGTAAAACCAGCCGAGCAAACGCCTACCAGCATTATGTGCCTTATGGAGTTGATCGATGGCATTCTTCCTCCGGGAG
TTTTAAATGTAGTTACAGGTTTTGGTCCAGAGGCAGGAAAACCTTTAGCCACTTCACCAAGAGTTGCCAAAGTTTCTTTT
ACAGGAGAAACAACAACAGGTCGTTTGATTATGCAGTATGCATCGGAAAACTTAGTACCTGTGACAATGGAGTTGGGAGG
TAAGTCTCCAAATGTTTTTATGAAATCAGTAGGTGATGCGGATGATGAGTTTTTTGACAAAGCAGTAGAGGGAGCCGTGA
TGTTTGCCTTAAATCAAGGTGAGGTGTGCACCTGTCCGTCTCGAATGTTGGTGCATGAGGATATTTACGACAAGTTTATG
GAGCGCGTAATAGCACGTACCAAAGCCATCAAAATGGGGAATCCTCTTGATCCTTCTACAATGATGGGAGCTCAGGCTTC
AAATGATCAGTATGAAAAGATTATGAGCTACCTAAATATTGGTAAAGAAGAAGGCGCTCAGGTACTTTGTGGAGGCGCTA
AGTTTTCACAAAATAGTGGACTTGAAGAAGGCTATTATGTGCAGCCAACCATCTTCAAAGGGCATAATAAGATGCGCGTA
TTCCAAGAGGAAATTTTTGGCCCTGTAGTGGCCGTTACCACTTTCAAAACTACAGAAGAAGCAATAGAAATTGCAAATGA
CACCATGTATGGATTAGGGGCAGGTCTCTGGACACGCGATGCTCATGAAATCTATCAAGTACCAAGAGCCATTCAGGCGG
GCCGTGTTTGGATAAATAATTACCATGCTTATCCTGCTCATGCTCCGTTTGGTGGGTACAAAAAATCTGGGTTTGGCCGT
GAAAATCACAAAATGATGCTCGATCATTATCGTCAAACCAAAAACATGCTGATTTCTTATGACAAGAAGAAATTAGGCTT
CTTTTAG

Protein sequence :
MEAATASFPFVGKSVEFKPKYEHFIGGEWVKPSNGEYFENISPINGQPFTQAARGTKADIELALDAAHKAFPSWSKTSAA
SRSNMLNKIAQVIEDNLEYLATIETIDNGKAIRECMAADLPLVIDHFRYFAGVIRADESTISEHDENTVSIALHEPLGVV
GQIIPWNFPLLMATWKVAPALAAGNCIVVKPAEQTPTSIMCLMELIDGILPPGVLNVVTGFGPEAGKPLATSPRVAKVSF
TGETTTGRLIMQYASENLVPVTMELGGKSPNVFMKSVGDADDEFFDKAVEGAVMFALNQGEVCTCPSRMLVHEDIYDKFM
ERVIARTKAIKMGNPLDPSTMMGAQASNDQYEKIMSYLNIGKEEGAQVLCGGAKFSQNSGLEEGYYVQPTIFKGHNKMRV
FQEEIFGPVVAVTTFKTTEEAIEIANDTMYGLGAGLWTRDAHEIYQVPRAIQAGRVWINNYHAYPAHAPFGGYKKSGFGR
ENHKMMLDHYRQTKNMLISYDKKKLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-143 60
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 5e-150 59
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 5e-150 59
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 5e-150 59
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-149 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Oweho_1614 YP_004989248.1 NAD-dependent aldehyde dehydrogenase VFG0082 Protein 8e-144 60