Gene Information

Name : GTCCBUS3UF5_34710 (GTCCBUS3UF5_34710)
Accession : YP_004983872.1
Strain : Geobacillus thermoleovorans CCB_US3_UF5
Genome accession: NC_016593
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3187297 - 3188937 bp
Length : 1641 bp
Strand : -
Note : similar to putative mercuric reductase PRK14727; similar to Mercuric reductase of Bacteria UniRef RepID=MERA_STAES

DNA sequence :
ATGAAAACATATCGAATGACCGTCCAAGGCATGACATGCACCGGTTGTGAACAACATGTCGCCAGAGCGCTGAGCGCGGT
TGGGGCTAAGCTGATGGATGTCAGCTTCCGGCGCGGTGAAGCAGTATTCGCGCTGCCCGAGGACGCCGACGTTGACATGG
CGAGACAAGCGGTCAAAAACGCTCATTACGAGCCGGGGGATATCGAGGAGGTCGCCGCACCAGCCAGCCCTGCCACTGCT
GGCGAAAGAGAGTATGACTACATCATCATTGGTTCCGGCGCGGCCGCGTTTTCTTCAGCGATTGAAGCCGTGAAATATGG
AGCGAAAGTCGCCATGGTCGAACGCGGCACAGTCGGGGGGACATGCGTCAATATCGGCTGCGTACCATCCAAGACATTGC
TTCGGGCCGGTGAAATCCAGGCGTTGGCACAGAATCATCCATTTCTTGGACTCCATACATCGGCCGGTCCGGTGGACTTG
GCGCTGTTAGTGAAGCAAAAAAATGAACTGGTCGAGCAGCTTCGCCAAGCGAAATATGCAGACTTGATCAGAGAGTACGG
GTTCGATTTCATCCGAGGGGAAGCACGATTTGTCGATGGTCAAACGATTGAAGTCAACGGCCAAACGCTGTCGGCGAAAC
GGTTTTTGATCGCGACAGGCGCTTCCCCGGCCGTGCCGGATATTCCGGGACTTCATGATGTCGACTACTTGACCAGCACG
ACCTTGCTTGAACTGGAAAAAGTGCCGAAGCGGCTCGCCGTCATCGGCGCCGGCTACATCGGGATGGAGTTGGGACAGCT
GTTCCACCATCTCGGCTCGGAGGTGACGTTGATGCAGCGAAGCTCGCGCCTGCTGAAAGAGTATGACCCGGAAATTTCCG
AAGCGATGACGCGGGCGCTCACAGAACAAGGCATCCGCGTCATCACCGGTGCTTCATTTGAACGGGTCGAACAAGATGGG
AATACGAAAAAAGTGTATGTGAACGTGGACGGACGCACCCGGGTCATCGAAGCGGACGAATTGCTCGTGGCTGCCGGGAG
AACGCCGAATACGGCGGCGTTGAACTTGCCGGCAGCCGGTGTGGAAGTCGGGGCGCGCGGGGAAATTTTGATCGACGAAT
ACACACGGACGACGAACCCGTCGATTTATGCGGCAGGCGATGTCACGCTCGGCCCGCAGTTCGTCTATGTCGCGGCCTAT
CAGGGAGCCGTTGCCGCGGCCAATGCCGTCGGCGGGCTGAACAAGCGCTGGGATACGGCCGTCGTTCCGGCGGTGACGTT
CACCCATCCGGCCATCGCCACTGTCGGTTTGACCGAACAGCGGGCGAAAGAAAACGGGTATGACGTGAAAACGTCCGTCC
TGCCGCTTGAGGCGGTGCCGCGCGCCATCGTCAACCGGGAAACGACGGGGGTGTTTAAACTTGTCGCTGAGGCCCGTACG
GGCAAGCTGCTGGGCGCCCACATCGTCGCTGACCATGCCGGCGAGGTCATTTACGCCGCAGCGTTGGCGATTCAATTCGG
ATTAACGATCGACGACCTTCGCCGAACGTTGGCCCCGTATTTAACGATGGCGGAAGGGCTGAAGCTGGCGGCGCTGACGT
TTGACCAAGATGTCTCGAAACTGTCGTGCTGTGCGGGGTAA

Protein sequence :
MKTYRMTVQGMTCTGCEQHVARALSAVGAKLMDVSFRRGEAVFALPEDADVDMARQAVKNAHYEPGDIEEVAAPASPATA
GEREYDYIIIGSGAAAFSSAIEAVKYGAKVAMVERGTVGGTCVNIGCVPSKTLLRAGEIQALAQNHPFLGLHTSAGPVDL
ALLVKQKNELVEQLRQAKYADLIREYGFDFIRGEARFVDGQTIEVNGQTLSAKRFLIATGASPAVPDIPGLHDVDYLTST
TLLELEKVPKRLAVIGAGYIGMELGQLFHHLGSEVTLMQRSSRLLKEYDPEISEAMTRALTEQGIRVITGASFERVEQDG
NTKKVYVNVDGRTRVIEADELLVAAGRTPNTAALNLPAAGVEVGARGEILIDEYTRTTNPSIYAAGDVTLGPQFVYVAAY
QGAVAAANAVGGLNKRWDTAVVPAVTFTHPAIATVGLTEQRAKENGYDVKTSVLPLEAVPRAIVNRETTGVFKLVAEART
GKLLGAHIVADHAGEVIYAAALAIQFGLTIDDLRRTLAPYLTMAEGLKLAALTFDQDVSKLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 3e-171 66
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 2e-171 66
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 4e-80 45
merA AGK07021.1 MerA Not tested SGI1 Protein 2e-78 44
merA AGK07079.1 MerA Not tested SGI1 Protein 2e-78 44
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 2e-77 44
merA ABQ57371.1 MerA Not tested SGI1 Protein 2e-78 44
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 2e-77 43
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 3e-75 43
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 2e-75 43
merA AFG30120.1 MerA Not tested PAGI-2 Protein 2e-75 43
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 1e-77 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GTCCBUS3UF5_34710 YP_004983872.1 mercuric reductase BAC0224 Protein 0.0 70
GTCCBUS3UF5_34710 YP_004983872.1 mercuric reductase BAC0651 Protein 1e-171 66
GTCCBUS3UF5_34710 YP_004983872.1 mercuric reductase BAC0650 Protein 2e-73 46
GTCCBUS3UF5_34710 YP_004983872.1 mercuric reductase BAC0652 Protein 6e-76 43
GTCCBUS3UF5_34710 YP_004983872.1 mercuric reductase BAC0653 Protein 8e-76 41