Gene Information

Name : GTCCBUS3UF5_910 (GTCCBUS3UF5_910)
Accession : YP_004980520.1
Strain : Geobacillus thermoleovorans CCB_US3_UF5
Genome accession: NC_016593
Putative virulence/resistance : Virulence
Product : negative regulator of genetic competence
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 98448 - 100880 bp
Length : 2433 bp
Strand : +
Note : similar to clpC Clp protease ATP binding subunit CHL00095; similar to Negative regulator of genetic competence clpC/mecB of Bacteria UniRef RepID=CLPC_BACSU

DNA sequence :
ATGATGTTTGGCAGATTTACGGAACGGGCGCAAAAAGTGCTGGCGCTGGCGCAGGAAGAAGCCATTCGCCTCGGCCATAA
CAATATCGGCACAGAACATATTTTGCTCGGCCTCATCCGCGAGGGCGAGGGGATCGCGGCTAAGGCGCTCATGGCGCTTG
GGCTCGGCCCAGATAAAATTCAAAAAGAAGTCGAATCGCTCATCGGCCGTGGCAGTGAAGTGTCGCATACGATCCACTAT
ACGCCGCGGGCGAAAAAAGTAATTGAGCTGTCGATGGATGAAGCGCGGAAGCTCGGCCATTCATACGTCGGCACAGAACA
TATTTTGCTTGGGTTGATCCGCGAAGGCGAAGGGGTGGCCGCCCGCGTGCTGAACAACTTGGGAGTAAGCTTGAACAAAG
CGCGCCAGCAAGTGTTGCAGCTGCTTGGCAGCAATGAGTCGATGTCAGGCCATGGCGGCGGTGCTTCGCACGTGAGCACT
CCGACGCTTGACAGCCTCGCCCGCGATTTGACAGCGATTGCCCGCGAAGGGCGGCTGGACCCGGTCATCGGCCGCAGTAA
AGAAATTCAGCGCGTCATTGAAGTATTAAGCCGGCGGACGAAAAATAATCCTGTGTTGATCGGCGAGCCGGGCGTTGGGA
AAACGGCCATTGCTGAAGGGTTAGCCCAACAAATCGTCAATAACGAAGTGCCGGAAACGCTGCGCGACAAGCGGGTCATG
ACGCTCGATATGGGGACAGTCGTCGCCGGAACGAAATACCGTGGAGAATTTGAAGACCGACTGAAAAAAGTGATGGATGA
AATTCGTCAAGCGGGCAACATCATCTTGTTTATCGATGAGCTGCATACATTAATTGGCGCCGGTGGGGCGGAAGGAGCGA
TCGACGCGTCGAACATTTTGAAACCGGCGTTGGCGCGCGGGGAGCTTCAATGCATCGGCGCGACAACGCTCGATGAATAC
CGGAAATATATTGAAAAAGACGCCGCGCTTGAACGCCGCTTTCAGCCGATTTACGTTGATGAACCGACAGTGGAAGAATC
GATCCAAATTTTAAAAGGGTTGCGCGATCGGTATGAAGCGCATCACCGCGTTTCGATTTCCGACGAGGCGATCGTGCAAG
CCGTCAAGTTGTCCGACCGCTACATTACCGACCGTTTCTTGCCGGATAAGGCGATCGATTTGATCGACGAGGCTTGCTCG
AAAGTGCGCCTTCGTTCGTTCACCGCACCGCCGAAATTGAAAGAACTTGAACAAAAGCTCGAGGAAGTGCGGAAAGAAAA
AGACGCGGCCGTGCAAAGCCAAGAGTTTGAGAAAGCGGCGTCGCTGCGCGATATGGAACAGCGGCTGCGCGAAGAACTGG
AGGAAACGAAACGTGCGTGGAAAGAAAAACAAGGCCAAGAAAATTTGGAAGTGACGGTCGAAGACATCGCCGCGGTCGTC
TCGAGTTGGACCGGCATTCCGGTATCGAAGCTCGCTGAGACGGAAACGGAGCGGCTGCTCAAGCTGGAAGAAATTTTGCA
TTCGCGTGTCGTCGGCCAAGACGAGGCGGTCAAAGCGGTCGCCAAAGCGGTGCGCCGCGCCCGTGCTGGCCTGAAAGACC
CGAAACGCCCGATCGGTTCGTTCATTTTCCTTGGTCCGACCGGGGTTGGGAAAACGGAGTTGGCTCGAGCCTTGGCAGAA
GCGATGTTTGGCGATGAAGACGCCCTCATTCGCATCGATATGTCCGAGTATATGGAAAAACACTCGACATCGCGGCTCAT
CGGGTCGCCGCCGGGGTATGTCGGTTATGAAGAAGGCGGCCAGCTGACGGAAAAAGTGCGCCGCAAGCCGTATTCGGTTG
TCCTGTTAGATGAGATGGAAAAAGCGCATCCGGACGTGTTCAATATTTTGCTGCAAGTGTTGGAAGATGGGCGGCTGACT
GACTCGAAAGGGCGGACGGTCGACTTCCGCAACACGATCATCATCATGACGTCCAACGTCGGCGCCGATGCGCTGAAACG
GAATAAGTACGTTGGCTTCAACATTCAAGACGGGAACCAGCAATACAAAGATATGAAAAGCAAAGTGATGGATGAGCTGA
AAAAAGCATTCCGTCCAGAGTTTTTAAACCGGATCGACGAAATCATCGTCTTCCATTCGCTCGAAAAAGACCATCTGAAA
CAAATCGTCCGATTGATGGCCGATACGCTCGTGAAGCGGCTGAAAGAGCAAGACATTGATCTTGAGCTGACGGAGGCCGC
CATTGAGAAAATCGCCGCCGAAGGGTTCGATCCAGAATACGGTGCCCGCCCGCTGCGCCGCGCCTTGCAAAAGCATGTTG
AAGACCGTTTGTCCGAAGAATTGTTAAAAGGCACGATCGCCAAAGGGCAAAAAGTCGTCGTGGATGTCAAAGACGGGGAG
TTTGTCGTATTGTCGAAACAAGCGGTCGTGTGA

Protein sequence :
MMFGRFTERAQKVLALAQEEAIRLGHNNIGTEHILLGLIREGEGIAAKALMALGLGPDKIQKEVESLIGRGSEVSHTIHY
TPRAKKVIELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNESMSGHGGGASHVST
PTLDSLARDLTAIAREGRLDPVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIVNNEVPETLRDKRVM
TLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPALARGELQCIGATTLDEY
RKYIEKDAALERRFQPIYVDEPTVEESIQILKGLRDRYEAHHRVSISDEAIVQAVKLSDRYITDRFLPDKAIDLIDEACS
KVRLRSFTAPPKLKELEQKLEEVRKEKDAAVQSQEFEKAASLRDMEQRLREELEETKRAWKEKQGQENLEVTVEDIAAVV
SSWTGIPVSKLAETETERLLKLEEILHSRVVGQDEAVKAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAE
AMFGDEDALIRIDMSEYMEKHSTSRLIGSPPGYVGYEEGGQLTEKVRRKPYSVVLLDEMEKAHPDVFNILLQVLEDGRLT
DSKGRTVDFRNTIIIMTSNVGADALKRNKYVGFNIQDGNQQYKDMKSKVMDELKKAFRPEFLNRIDEIIVFHSLEKDHLK
QIVRLMADTLVKRLKEQDIDLELTEAAIEKIAAEGFDPEYGARPLRRALQKHVEDRLSEELLKGTIAKGQKVVVDVKDGE
FVVLSKQAVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 59
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-88 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GTCCBUS3UF5_910 YP_004980520.1 negative regulator of genetic competence VFG0079 Protein 0.0 79
GTCCBUS3UF5_910 YP_004980520.1 negative regulator of genetic competence VFG0080 Protein 3e-141 53