Gene Information

Name : merA (BYI23_E002730)
Accession : YP_004980221.1
Strain :
Genome accession: NC_016591
Putative virulence/resistance : Resistance
Product : putative MerA, mercuric ion reductase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 233333 - 234763 bp
Length : 1431 bp
Strand : -
Note : -

DNA sequence :
ATGTCAGACTGCTGCACCACCGAAGGAAGCCGTAAGGGCGGCTACGACCTTGCCGTCATCGGCGCCGGATCGGCCGGATT
CTCGGCCGCGATCACCGCCGCCGATCAGGGCGCCAATGTCGCGCTGATCGGCCACGGCACCATCGGCGGCACCTGCGTCA
ATGTCGGCTGCGTGCCGTCGAAGACGATGATCCGCGCGGCCGAGGCGCTGCATGGTGTGCGGGCCGCGCAACGCTTTCCC
GGCCTGGTCGGGGAAGCAAGCGTGGCCAACTGGCCCGCGCTCGTCGCGGCCAAGGACGAGCTGGTCACCAGCTTGCGGCA
GAAGAAATATATTGACCTGCTGCCCGAGTACAACGGCGTTGCCTATCTGGAAGGCGCGGCGCGTCTGAACGGGCAGGGCG
TGATGGTGAATGGCGCCGCGATTTCAGCGGGCAAGATCATCATCGCGACCGGCACCTCGCCGGCCCTGCCGGACATTCCC
GGCATTGAGGAGGTGCCTTATCTCACCAGCACGACTGCCCTGGAACTTGGCGCGCTACCGCGCTCATTGCTCGTCATCGG
CGGCGGCTATATCGGCTGCGAACTGGCGCAGATGTTCGCGCGCGTCGGCGTGGCGGTGACGCTCATCACCCGCCGCCGCT
TGCTGCCGGAGGCCGAGCCGGAAATCTCCGAGGCGCTGACCGGCTATCTCCGCGACGAGGGCATTACCGTCCGGACCGGA
CTAACTTATCGCGGAATCGCGCGCACGGCTGCCGGCGTCGAGCTGAGTATCACCACCGACGGCGCACAGCAGGTGATCGC
CGCCGAGCAGGTGCTCGTAGCCACCGGACGGGCGCCGAATACCGATGGCCTCGGCCTTGTCGAAGCGGGCATCGCCCAAG
CCGACAACGGCAGTGTGGTCGTGGACGACCGGATGCGCACCTCGAGACCGGATGTCTATGCGGCCGGCGACGTCACCGGT
CGCGATCAGTTTGTCTATATGGCGGCCTATGGCGCGAAGCTCGCCGCGCACAACGCGCTGAACGGCGACGACCTCGTCTA
CGACAATACGGTCATGCCCTGGGTCACGTTTACCGACCCACAGGTGGCGGGCGTGGGACTGAGCGAAAGGGCAGCGCAGG
CAGCGGGCTTCGAGACCAAGACCTCGATCGTCGCCCTCGACCAGGTGCCGCGGGCACTGGCCGCTCGCGACACACGGGGG
TTGATCAAGCTGGTCGCTGACAAAACGTCCGATCGCCTGCTGGGCGGTCAAATCGTCGCGCCCGAGGGAGCCGACAGCAT
CCAGACCATGGTGCTCGCGATCAAACACGGCATGACGACGAAGGCGCTGGGCGAGACGATCTTTCCCTATCTCACCACGG
TCGAGGGCCTGAAACTCGCCGCACAGGGCTTCGGCAAGGATGTGGCAAAACTGTCCTGCTGCGCAGGATGA

Protein sequence :
MSDCCTTEGSRKGGYDLAVIGAGSAGFSAAITAADQGANVALIGHGTIGGTCVNVGCVPSKTMIRAAEALHGVRAAQRFP
GLVGEASVANWPALVAAKDELVTSLRQKKYIDLLPEYNGVAYLEGAARLNGQGVMVNGAAISAGKIIIATGTSPALPDIP
GIEEVPYLTSTTALELGALPRSLLVIGGGYIGCELAQMFARVGVAVTLITRRRLLPEAEPEISEALTGYLRDEGITVRTG
LTYRGIARTAAGVELSITTDGAQQVIAAEQVLVATGRAPNTDGLGLVEAGIAQADNGSVVVDDRMRTSRPDVYAAGDVTG
RDQFVYMAAYGAKLAAHNALNGDDLVYDNTVMPWVTFTDPQVAGVGLSERAAQAAGFETKTSIVALDQVPRALAARDTRG
LIKLVADKTSDRLLGGQIVAPEGADSIQTMVLAIKHGMTTKALGETIFPYLTTVEGLKLAAQGFGKDVAKLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 5e-81 49
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 3e-95 48
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 2e-95 48
merA AGK07079.1 MerA Not tested SGI1 Protein 5e-79 47
merA ABQ57371.1 MerA Not tested SGI1 Protein 5e-79 47
merA AGK07021.1 MerA Not tested SGI1 Protein 5e-79 47
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 1e-78 47
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 1e-78 47
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 4e-78 46
merA AFG30120.1 MerA Not tested PAGI-2 Protein 4e-78 46
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 5e-78 46
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 1e-77 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA YP_004980221.1 putative MerA, mercuric ion reductase BAC0651 Protein 1e-95 48
merA YP_004980221.1 putative MerA, mercuric ion reductase BAC0653 Protein 3e-80 47
merA YP_004980221.1 putative MerA, mercuric ion reductase BAC0652 Protein 5e-79 47
merA YP_004980221.1 putative MerA, mercuric ion reductase BAC0650 Protein 2e-75 45