Gene Information

Name : pchD (AZOLI_p20159)
Accession : YP_004974480.1
Strain :
Genome accession: NC_016586
Putative virulence/resistance : Virulence
Product : 2,3-dihydroxybenzoate-AMP ligase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 140190 - 141851 bp
Length : 1662 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9485415; Product type e : enzyme

DNA sequence : 
ATGTCCGCTCCTGTCACGGCCACGATGCACCCAACTGCGCCGGATTGGCCCCCCGAATTCGTGGAACGCTATGTTTCCGC
TGGCTTCTGGAGATCCGAGACCTTCGGCGGGGTCCTGAAGACCGTGGCCGGGCGGATGGGGGCACAGATCGCGCTGGTCG
ATGGGGACCGGCGCCTGTCGTTCGAGGAGCTCGACCGTTCCGTCGATGAACTGGCCGCCGGATTTGCCGGGTTGGGGCTT
GGCAAAGGCGATGTCGTCGTCGTCCAGCTTCCGAACCGCGCGGCGTTCGTCGAGGTCGTCTTCGCCCTGTTCAGGCTGGG
CTCGGTTCCGGTTTTCGCGCTGCCCGCCCACCGATCCGTCGAGATCGGGGCATTCTGCAGCTTCACCGGGGCAAAGGCCT
ACATCGTGGCCGATGTCGTCGGCGGCTTCGATTATCGGGAGCTGGCCGCCGACATCCGCGCCCGCGCGCCCTCGCTTGCC
CATGTCATCGTCGACGGCGAGCCCGGCCCTTTCCTGGCGCTCGACGGGTTGCGGCGGCCGCCTGTCGACTTGCCGGCCAT
CGACGCCGGCGATCTGGCCTGTTTCCAGCTTTCCGGCGGGACGACCGGCATTCCCAAGCTGATCGCACGCCGTCATCGCG
ACTATCTCTATAATGTCAGGGCGAGTGTGGAGGCGTGCGACTTCAACGAACGCACGGTCTACCTCGCCGCTTTGCCGATG
GGGCATAATTTCCCGATGGCGTGCCCCGGCTTCCTGGGCACCCTTCTTGCCGGCGGACGGGTGGTGGTGACGGACCGGCC
GACCCCGGACGTCTGTTTCGACCTCATCGCCCGCGAGAACGTCACCGCCACCGCGCTGGTTCCGCCGTTGGCGATGGTCT
GGCTCGATGTGGCGGAGATGACGAAGCCGCAGGTACCGAGCCTGCGCATTCTGCAGGTCGGCGGCGCCAAGCTCGGCCAT
GAAGCGGCCCGTCGTGTCGCTCCGGCCCTGGGGTGCAGGCTGCAACAGGTCTTCGGCATGGCCGAGGGTCTGATCTGCTT
CACCGCGCCGGAGGATCCCGACGATGTGGTTCTCAACACCCAAGGCAAGCCGATGTCGACGGCCGACGAAGTGCGGATCG
TCGATGGCGACGGCAACGACGTGCCCGACGGCGTCACCGGGCATTTGCTGACCAGGGGACCTTACACCATACGCGGCTAC
TTCGGCCTGTCCGAGCAGAACGCCGCATCCTTCACGCCCGATGGATTTTACCGCAGCGGCGATCTGGTCAGGCGCGTTGC
CGGCGGCCAACTCGTCGTCGAGGGACGTGACACCGATCAGATCAATCGTGGTGGCGAGAAGATCGCGGCGGAGGAGGTCG
AGAATTTCCTGCTCGGCCATGAGGGCGTGCTCGACGTGGCGGTCGTGGGGTTGCCGGACGGCTATCTGGGCGAACGTACC
TGCGCCTTCGTGCTGCCGCGGTCGTCGCGTCCGACACCGAACGATCTGCGGATGTTCCTCAAGGCCAGCGGACTTGCCGC
CTTCAAGATTCCGGATCGCTTCGAGTTCCTCGACAGCTTTCCCACGACGGGGGTCGGCAAGATCAGCCGCAAGACGCTGC
GCGAGACCCTGAAGGCGATGCATTCAGGGGCCGGGGCCGCCTCGGCCGCCGCCGCCGAATAG

Protein sequence : 
MSAPVTATMHPTAPDWPPEFVERYVSAGFWRSETFGGVLKTVAGRMGAQIALVDGDRRLSFEELDRSVDELAAGFAGLGL
GKGDVVVVQLPNRAAFVEVVFALFRLGSVPVFALPAHRSVEIGAFCSFTGAKAYIVADVVGGFDYRELAADIRARAPSLA
HVIVDGEPGPFLALDGLRRPPVDLPAIDAGDLACFQLSGGTTGIPKLIARRHRDYLYNVRASVEACDFNERTVYLAALPM
GHNFPMACPGFLGTLLAGGRVVVTDRPTPDVCFDLIARENVTATALVPPLAMVWLDVAEMTKPQVPSLRILQVGGAKLGH
EAARRVAPALGCRLQQVFGMAEGLICFTAPEDPDDVVLNTQGKPMSTADEVRIVDGDGNDVPDGVTGHLLTRGPYTIRGY
FGLSEQNAASFTPDGFYRSGDLVRRVAGGQLVVEGRDTDQINRGGEKIAAEEVENFLLGHEGVLDVAVVGLPDGYLGERT
CAFVLPRSSRPTPNDLRMFLKASGLAAFKIPDRFEFLDSFPTTGVGKISRKTLRETLKAMHSGAGAASAAAAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 3e-99 50
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 5e-99 50
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 6e-99 50
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 6e-99 50
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 6e-99 50
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 6e-99 50
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 6e-99 50
ybtE CAA21394.1 - Virulence HPI Protein 6e-99 50
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 5e-99 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pchD YP_004974480.1 2,3-dihydroxybenzoate-AMP ligase VFG0168 Protein 6e-142 58
pchD YP_004974480.1 2,3-dihydroxybenzoate-AMP ligase VFG1817 Protein 6e-97 47
pchD YP_004974480.1 2,3-dihydroxybenzoate-AMP ligase VFG0932 Protein 5e-96 43