Gene Information

Name : Desor_2023 (Desor_2023)
Accession : YP_004970147.1
Strain : Desulfosporosinus orientis DSM 765
Genome accession: NC_016584
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2137595 - 2139331 bp
Length : 1737 bp
Strand : +
Note : PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase

DNA sequence :
GTGAGAAGGACAAAGATTGTCTGTACAATTGGTCCGGCAAGTGAGTCCAGGGAACAGGTTCAAGCTCTTTTAGCTGCCGG
TATGGATGTTGCCCGGCTGAATTTTTCACATGGGACCCATGAAGAACACGCCCGGAGAATAGTCATTCTGAAAGAGGAAG
CGGCTAAGGCAGGAAAGCATCTGGCAATCCTTTTGGATACGAAAGGGCCGGAAGTGCGCACCGGCAAAGTCCCGGAAGAA
GGGGTTAACCTGGTTAACGGCTCGCCCTTCCGCTTGGATACCGACCTAAGCAGCTTAGGAGATCAGCGCCGGGTGGGGAT
TACTTATGCCAATTTATGGCGCAAAGTTAAACCCGGCAGTCATATTCTCATTGACGACGGTCAAATTGAACTGGAAGTAA
CTTCTGTCCAGGAGCAGATCATTGAGACTGTCATCCTTAACGGCGGAGTGCTTAAATCCCAAAAAGGGGTTAATACGCCC
AATGCTCTGATTGATTTACCTGCTGTTACAGAAAAAGACATAGAGGATATTCGTTTTGGCATTGCCCAGGGAATTGACTT
TATCGCCGCTTCTTTTACCCGTAAGGCCCTGAATATTTTAGATGTGCGCAAGGTTGTCGAGGAAATGGGAGCGGATGTGC
ATATTATTGCTAAAATAGAAAGCCGGGAAGGCCTGGACAACTTGGATGCCATCCTGGAGGTGGCAGACGGTCTTATGGTT
GCCCGGGGGGATCTGGGGGTTGAAATTCCCGTTGAGGAAGTACCTATCCGCCAGAAAGAAATGATCCGCAAATGCAATTT
GCTGGGTAAGCCGGTTATAGTCGCCACTCAGATGCTGGATTCTATGATTCGCCAGCCCCGGCCCACCAGGGCGGAAGCCA
GTGATGTGGCTAATGCCATCCTGGATGGGACGGATGCGATTATGTTATCCGGAGAGACCGCCGCAGGACTCTATCCCATT
GGAGCGGTTCAGATGATGGATAAAATCGCCAGGCAAACCGAGCAGACCTGTCTGGAGAACCGGGCTACCCGCCACCCTCA
GGTTAACGTGGCAGAAGCTATTAGTTTTGCCAGTTATACTGTCGCCAAGGATCTCCAGGCGGCGGCCATACTCACCCCTA
CCCATTCGGGTCTGACGGCCCGCATGATCTCCAAATACCGCCCCGTAGCCTTGCTTGTGGCAGCAACTCCCTTTGCAGAA
ACGGCCAGGAAGCTGGCCTTACAGTGGGGTGTCCAGCCCTTAGTGGTTCCGGAAAGTTCAGGAACGGATGAAATGGTTTC
TGTTGCTGTTAATTCATCCTTGAATAAAAACTATATCCAATCCGGTGATATCGTCGTGATCACTGCCGGGGTTCCCATCG
GAAAAGTCGGCTCGACAAATATGATTAAGGTGCAAATTATGGGCAATATTTTAGCAAAAGGGACGGGAATCGGACGCAAG
TCCTATTCCGGTACCGCCCGGAGGGTTCAGACCCCCGGTGAGGATACCTTCAATGACGGGGAAATTTTAATTGCGTCTTC
AACGGATGCCCGGTTTGTCCCCTTAATTGCCCGGGCGGGAGCCTTAGTCGTGGAAGAAGGCGGCCTGACCTCCCATGCTG
CCATTGTCGCCGTACAATTCGGCATTCCCACCATTGTCGGAGCCGCAGATGCTATGGCAAAGGTGAGCGACGGACAATCT
ATGACCGTCGATGCCATGACAGGATTAATGTATGAAGGCTCTGTCAGCATTCTTTAA

Protein sequence :
MRRTKIVCTIGPASESREQVQALLAAGMDVARLNFSHGTHEEHARRIVILKEEAAKAGKHLAILLDTKGPEVRTGKVPEE
GVNLVNGSPFRLDTDLSSLGDQRRVGITYANLWRKVKPGSHILIDDGQIELEVTSVQEQIIETVILNGGVLKSQKGVNTP
NALIDLPAVTEKDIEDIRFGIAQGIDFIAASFTRKALNILDVRKVVEEMGADVHIIAKIESREGLDNLDAILEVADGLMV
ARGDLGVEIPVEEVPIRQKEMIRKCNLLGKPVIVATQMLDSMIRQPRPTRAEASDVANAILDGTDAIMLSGETAAGLYPI
GAVQMMDKIARQTEQTCLENRATRHPQVNVAEAISFASYTVAKDLQAAAILTPTHSGLTARMISKYRPVALLVAATPFAE
TARKLALQWGVQPLVVPESSGTDEMVSVAVNSSLNKNYIQSGDIVVITAGVPIGKVGSTNMIKVQIMGNILAKGTGIGRK
SYSGTARRVQTPGEDTFNDGEILIASSTDARFVPLIARAGALVVEEGGLTSHAAIVAVQFGIPTIVGAADAMAKVSDGQS
MTVDAMTGLMYEGSVSIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-93 47
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-93 47
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-93 47
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-93 47
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 1e-59 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Desor_2023 YP_004970147.1 pyruvate kinase VFG0479 Protein 8e-94 47