Gene Information

Name : fepC (SBI_08219)
Accession : YP_004966468.1
Strain : Streptomyces bingchenggensis BCW-1
Genome accession: NC_016582
Putative virulence/resistance : Virulence
Product : iron-siderophore uptake system ATP-binding component
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 9714482 - 9715480 bp
Length : 999 bp
Strand : +
Note : COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components

DNA sequence :
ATGGGTGGCACGGGCGGTGCGGGCGGTATGGGTGGTACCGGCAAGGGTGCCCGGTCGCAGCGGCTCACCGCCGAAGGGCT
CACCCTCGCCTACGACCGGCGCACGGTGGCCGAGGGCCTGACCGTCGCCATCCCCGACCACTCCTTCACGGTGATCGTCG
GGCCCAACGCGTGCGGCAAGTCCACCCTGCTGCGCGCGCTGTCCCGGATGCTCAAGCCGACCGCCGGGTCGGTGCTGCTG
GACGGGCAGGCGATCGGCTCGATGCCCGCCAAGAAGGTCGCCCGCACCCTCGGGCTGCTGCCGCAGTCCTCGATCGCGCC
GGACGGCATCACCGTCGCGGACCTGGTCGCCCGCGGCCGCTATCCGCACCAGGGGCTGCTGCGGCAGTGGTCGGAGACGG
ACGAGCGGATTGTCGGCGAGTCGATGGCGGCGACCGGCGTGGCCGAGCTCGCGGATCGCTATGTCGATGAATTGTCGGGC
GGTCAGCGGCAGCGGGTGTGGATCGCCATGGCCATCGCCCAGCAGACCCCGCTGCTGCTCCTCGACGAGCCGACCACCTA
CCTGGACATCCAGCACCAGATCGATGTGCTCGACCTGTGCGCCCAGCTCCACGAAGAGCAGGGCCGCACCCTCGTCGCCG
TCCTCCACGACCTCAACCACGCCGCCCGCTACGCCACCCACCTGATCGCGATGCGCGGCGGGGAGGTCGTCGCCGAGGGC
GCGCCCGGGGAGGTGGTGACGGCCGAGCTGGTGGAGCGGGTCTTCGGGCTGCGCTGCCAGGTGATCGACGACCCCGAGAC
CGGCACCCCGCTGGTGGTGCCCGCCGCCCGGCGGTCCCGTACGCGGACGGATGGGGCGCCGACGAAGGCTATGGCGGCAG
AGGCCCCAGGCGCGAAGGCCACGGCCCCGGGCGTGACGGAGGCGCCGGCGACGGAGATGGCCGCGGCTACAGCAGCTTCC
GCAGCCGCAGAAGATCGCGGAAGCCGGCCTCCAGCTTGA

Protein sequence :
MGGTGGAGGMGGTGKGARSQRLTAEGLTLAYDRRTVAEGLTVAIPDHSFTVIVGPNACGKSTLLRALSRMLKPTAGSVLL
DGQAIGSMPAKKVARTLGLLPQSSIAPDGITVADLVARGRYPHQGLLRQWSETDERIVGESMAATGVAELADRYVDELSG
GQRQRVWIAMAIAQQTPLLLLDEPTTYLDIQHQIDVLDLCAQLHEEQGRTLVAVLHDLNHAARYATHLIAMRGGEVVAEG
APGEVVTAELVERVFGLRCQVIDDPETGTPLVVPAARRSRTRTDGAPTKAMAAEAPGAKATAPGVTEAPATEMAAATAAS
AAAEDRGSRPPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 3e-57 51
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 7e-58 50
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 7e-58 50
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 7e-58 50
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 7e-58 50
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 1e-53 47
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 1e-53 47
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 3e-44 46
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 2e-46 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fepC YP_004966468.1 iron-siderophore uptake system ATP-binding component BAC0164 Protein 2e-44 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fepC YP_004966468.1 iron-siderophore uptake system ATP-binding component VFG0925 Protein 1e-70 61
fepC YP_004966468.1 iron-siderophore uptake system ATP-binding component VFG1042 Protein 2e-44 46