Gene Information

Name : ANH9381_2211 (ANH9381_2211)
Accession : YP_004949836.1
Strain : Aggregatibacter actinomycetemcomitans ANH9381
Genome accession: NC_016513
Putative virulence/resistance : Virulence
Product : hemolysin D
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2108061 - 2109494 bp
Length : 1434 bp
Strand : -
Note : -

DNA sequence :
ATGAAAACTTGGCTTTTGGCATTGTATGATGTGCTTTCCCGTTATAAAAACGTGTGGAATGAAACTTGGAAAATTCGTAA
ACAGCTTGATTCTCCGATTAGAGAAAAAGATGAAAATGAATTTCTGCCCGCGCATTTGGAATTAATTGAGACACCTGTAT
CAAATGCACCACGATTCGTGTCTTATTCCATTATGCTCTTTTTAACTTTAGCGATTATTGTTTCTATCTTTAGCAATGTG
GAAATTATCGCAACCGCTTCAGGAAAATTCGCACTAAGCGGGAGAAGCAAAGAAATTAAACCGATTGAAAATTCATTGGT
TAAAGATATTTTTGTGAAAGAGGGCGAATACGTGAAAAAGGGTGAACTATTGTTAAAACTGACCGCACTTGGTGCCGAAG
CGGATACGTTAAAAACGAAGACATCGCTTTCTCAAGCTAAACTAGAGGAATTTCGTTATAAATCTTTATTGGAAGCTGTT
GAAAAAGATCAATTACCAATATTAGATTTTTCTAAAATTGATTTGCCTTTTATGACGGAAAACGATCAAAAAAGGGTGAC
TTTACTGATTGAAGAGCAATTCTCTACTTGGCAAAAACAACGCCATCAGAAAACCTTGAATCTTAATAAAAAAGAAGCAG
AAAAACTCAGTTATTTGGCACGAATAAAAAAATATGAGGGTTTGATTAATACAGAACAAGTCCGATTGGATGATTTTAGA
GCCTTATATAAGGAACATGCTATTGCAAAACATACGGTTTTAGATGAAGAAAATAAATATCAGGATGCAATCAATGAGCT
TGAAGTATATAAGGCGAGTTTAATGCAAGTTGAAAATGAAGTTTTATTGGCCAAAGAAGAGCAGGAATTAGTCACACAAT
TGTTCAAAAATGATATTTTAGACAAGCTAAAACAGGCGACGGATAATGTGAATTTATTGACATTCGAGCTGGACAAAAAC
AATCAACGCCAGCAAGTCTCTGAAATTCGAGCCCCTGTATCGGGTACTGTACAGCAATTAAAGGTTCACACAATAGATGG
CGTTGTTACTACGGCTGAAACATTAATGGTAGTTGTGCCGGAAGAAGATTCCCTTGAAGTCACCGCACTTATTCAAAATA
AAGATATTGGTTTTGTGAAAGAAGGGCAAGACGTCGTAATTAAGGTTGAAGCCTTCCCCTATACCCGTTATGGCTACTTA
ACAGGAAAAGTGAAAAATATTACTTTAGATGCGATTGAACATCCAAAGCTTGGACTTGTATTTAATACAATTATTGAATT
GGATAAAAAAACACTTTCTACCGAAGAAAAAGAAATCCCGCTTTCTGCAGGGATGGAAATTACTGCAGAAATTAAGACAG
GCATGAGAAGTGTTATAAGCTATCTACTCAGCCCATTAGAAGAATCTATTGATAAAAGTTTAAGAGAACGTTAA

Protein sequence :
MKTWLLALYDVLSRYKNVWNETWKIRKQLDSPIREKDENEFLPAHLELIETPVSNAPRFVSYSIMLFLTLAIIVSIFSNV
EIIATASGKFALSGRSKEIKPIENSLVKDIFVKEGEYVKKGELLLKLTALGAEADTLKTKTSLSQAKLEEFRYKSLLEAV
EKDQLPILDFSKIDLPFMTENDQKRVTLLIEEQFSTWQKQRHQKTLNLNKKEAEKLSYLARIKKYEGLINTEQVRLDDFR
ALYKEHAIAKHTVLDEENKYQDAINELEVYKASLMQVENEVLLAKEEQELVTQLFKNDILDKLKQATDNVNLLTFELDKN
NQRQQVSEIRAPVSGTVQQLKVHTIDGVVTTAETLMVVVPEEDSLEVTALIQNKDIGFVKEGQDVVIKVEAFPYTRYGYL
TGKVKNITLDAIEHPKLGLVFNTIIELDKKTLSTEEKEIPLSAGMEITAEIKTGMRSVISYLLSPLEESIDKSLRER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlyD AAC61717.1 chromosomal hemolysin D Virulence PAI I CFT073 Protein 9e-142 68
hlyD CAD33761.1 Hemolysin D Virulence PAI I 536 Protein 2e-156 68
hlyD NP_755449.1 hemolysin D Virulence PAI I CFT073 Protein 1e-156 68
hlyD CAD42037.1 HlyD protein Virulence PAI II 536 Protein 2e-156 68

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ANH9381_2211 YP_004949836.1 hemolysin D VFG0908 Protein 5e-157 68
ANH9381_2211 YP_004949836.1 hemolysin D VFG1502 Protein 1e-156 68
ANH9381_2211 YP_004949836.1 hemolysin D VFG1556 Protein 1e-156 68
ANH9381_2211 YP_004949836.1 hemolysin D VFG0843 Protein 1e-118 53