Gene Information

Name : Tlie_0755 (Tlie_0755)
Accession : YP_004932585.1
Strain : Thermovirga lienii DSM 17291
Genome accession: NC_016148
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 789894 - 791702 bp
Length : 1809 bp
Strand : +
Note : PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; COGs: COG0469 Pyruvate kinase; InterProIPR018209: IPR015793: IPR015794: IPR008279: IPR 001697; KEGG: tai:Taci_0833 pyr

DNA sequence :
ATGAAAAAGAGAGTTAAGATAGTTTGTACCCTTGGTCCATCTTGCTCAAAATATGATGTTTTAAGGAATATGGTTCAGGC
GGGCATGAACGTTGCCCGCCTGAATTTTAGCCATGGTGACTACGAAAGCCATGGTAGGCTTTTGGATAACGCAAGAAGGG
CAGAAAAAGACTTGGGGATGCCCATTCCTATCATGATAGACACTAAGGGACCAGAAATAAGGACTGGAACATTGGCCGGA
CACGTACCTGTAGTTTTGAAAGGCGGTGATTTTCTAGTAATCACCACAAGACCGACCGAGGGGAACAAGGAAAAAATCTA
CGTGGACTATCCAGGTTTTGTAAGAGAAGTCGCTCCCGGAAGAACTATTTTTATTGACGATGGAAGGATCAGCCTCAAAG
TGGAGAAAATATTATCTGAAGAAGAAACCTTATGCAAGGTCGTGGTTGGTGGAGAGTTGGGCGAGAATAAGGGGGTTTCG
GTTCCGGGAGCTTTGAACAACTTGCCTATTCTTACGAAGAAAGACATCAATGACATAAAGTGGGCTATTTCAAGGGGAGC
AGACTACCTTGCCCTTTCTTTCGTCCGAACTAGGGAAGACGTCTTGAAGGCGCGAAAGCTCTTAGAGGACCTTGATGGTG
ATCTCCAGATCATATCTAAGATAGAGACAATGCAGGCTGTGAGGAACCTGGAAGAAATTATAGAGGTCTCTGATGGAGTA
ATGGTTGCCCGTGGAGATTTGGGAGTCGAGATCCCCTTGGAGGAAGTTCCAATGCAGCAGAAAAGGATCATAGATTTATG
TAGATTTGTTGGGAAACCTGTAATTGTGGCTACCCAGATGCTGGATTCCATGATAAGAAATCCCAGGGCAACCAGGGCTG
AGTGCAGTGATGTGGCTAACGCTGTGCTTGACGGAGCAGATGCCCTTATGCTTTCAGGTGAGACAGCGCAAGGTAAATAT
CCTGTAGAAGCAGTTCAAACGATGGCTAAAATAATAGAGAGAACGGAAAAGGATCCCCTCTTTTGGTCCATTACTTCCAA
CAAGGGCTATGAAAATATAAAGCGCATATCTGACGCTGTAGGAAACGCAGCAGTGATGATAGCAAAGAGAATGGATGCCC
ATGGTATTTTGTGCATGACCCAAAGTGGAAGTACTGCCCAGATAATCAGTAAGTACAGGCCTAAATCTAAAATAATAGGT
GCTACCCCTTCTGAAAAGATTTACAGAAAGCTGGGGCTTGTATGGGGAGTGCACCCCCTTAAGGTCAGCAAGGAAGAGAA
CCTGGAAAATGCTATAACTGCAGGGATCGAAAGGGCCTTGGAAGAAGGAATGTTGAATGAGGGAGACTTGGTAGTGGTTA
CTGCAGGAGTGCCGGTTGGCATATCTGGTACCACCAATATCATTGAGGTGGTTTCTGTGGGACAGATATTACTAAAGGGT
ATGTCGATAATGAAGAAAGTGGCCTGCGGGAAGGTGGTTACGGCACTTGATGGGGCAGAGGCTGCAATGAAGATTTCCTA
TGGAGACATATTGGTATGTAGGCAAACCGATAAGGGGTTCGTCGAAGCGGCCAAGAAAGCGTCTGCAATAATAGCGGAAG
AGGGAGGGCTTACCAGCCATGCAGCCATTTTATCACTGGAGCTGAGGATTCCTTGTATTGTGAGTGCCAAATCAGCCATG
ACGGTCCTGGAGGATGGTATGATAGTTACAGTTGATGGTAATAGAGGGATAGTATATAGGGGTAGGGTCCATTTGGAATC
GAAAGGCAATAAATCGGATGAATCAGGGGAGAATGTTGCTGGAAGATAA

Protein sequence :
MKKRVKIVCTLGPSCSKYDVLRNMVQAGMNVARLNFSHGDYESHGRLLDNARRAEKDLGMPIPIMIDTKGPEIRTGTLAG
HVPVVLKGGDFLVITTRPTEGNKEKIYVDYPGFVREVAPGRTIFIDDGRISLKVEKILSEEETLCKVVVGGELGENKGVS
VPGALNNLPILTKKDINDIKWAISRGADYLALSFVRTREDVLKARKLLEDLDGDLQIISKIETMQAVRNLEEIIEVSDGV
MVARGDLGVEIPLEEVPMQQKRIIDLCRFVGKPVIVATQMLDSMIRNPRATRAECSDVANAVLDGADALMLSGETAQGKY
PVEAVQTMAKIIERTEKDPLFWSITSNKGYENIKRISDAVGNAAVMIAKRMDAHGILCMTQSGSTAQIISKYRPKSKIIG
ATPSEKIYRKLGLVWGVHPLKVSKEENLENAITAGIERALEEGMLNEGDLVVVTAGVPVGISGTTNIIEVVSVGQILLKG
MSIMKKVACGKVVTALDGAEAAMKISYGDILVCRQTDKGFVEAAKKASAIIAEEGGLTSHAAILSLELRIPCIVSAKSAM
TVLEDGMIVTVDGNRGIVYRGRVHLESKGNKSDESGENVAGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-86 46
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-86 46
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-86 46
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-86 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tlie_0755 YP_004932585.1 pyruvate kinase VFG0479 Protein 4e-87 46