Gene Information

Name : Tlie_0602 (Tlie_0602)
Accession : YP_004932434.1
Strain : Thermovirga lienii DSM 17291
Genome accession: NC_016148
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 642205 - 643761 bp
Length : 1557 bp
Strand : +
Note : PFAM: GMP synthase C terminal domain; Glutamine amidotransferase class-I; NAD synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit; COGs: COG0519 GMP

DNA sequence :
ATGGGAAATTCAACTTCGGCAATTGAGGAAAAGGTTATAGTTCTAGACTGCGGTTCTCAGTACACTCAGCTCATAGCCAG
GAGGATAAGGGAGCTTGGCGTTTACAGTGAAATACTTCCTTGGGATACCCCTTACGAGGAAATAGCGCAACAATCCCCTA
AGGGTATAGTGATTTCAGGAGGTCCCTCCTCCGTTAGAGAGGAGGATTCCCCGACGGTCCCAGAGGACGTATTGAGTGGT
AAAGTTCCCGTACTTGGAATATGTTACGGCATGCAGCTTATTGCTCACATGTTGGGTGGAGTGGTCAAGAAAGGGCCCTT
CGCCGAGTACGGTAAGGCCACGGTTAATGTGACCGATCCAAATGCCGACATTTTCTATGGAGTTTCCTCCCCCCTTCAGG
TATGGATGAGCCACTGGGACTACGTGGAACAGCCCCCCAAAGGTTTCAAAGTGGCAGCCAGGAGCGAATCGGGAATGATA
GCGTCCATATATAACGATGACCTGAATGTATGGGCTCTTCAATTTCATCCCGAGGTGTGGCACACCCAGCAGGGCAGCAA
AATATTGGAAAACTTCCTTTTTAAGATATGTAAATGCAAGGGGCTTTGGGACCTAGAGGGCTGGATAGACATGATGACAA
AACAAATAAAAGAGACCGTAGGGCAAGACAAGGTCATATGTGGCCTTTCTGGCGGAGTGGACTCCACAGTGGCTGCAGTT
TTGACCCACAAGGCCATAGGGGACAACCTTGAATGTATTTTCGTAGACAACGGTCTCTTGAGGATGAACGAGGCCCAGGA
AGTGTTGAAAGTCTACGAGGATCTGCATCTGAAGGTCCATGCCGTAGATGCCAGAGAGGAGTTCCTTAGCGCCCTGAAAG
GTGTAACGGATCCAGAAAGAAAGAGGAAGATTATCGGTGAAATATTCATAAGGGTCTTCGAGAAAAAAGCCAACGAGATA
GGTGGCGCCAAGTGGCTGCTTCAGGGTACGGTGTACCCCGATGTGATAGAAAGCGGGAAGAAAGGTAAGGACGCTGCCGT
CATAAAGAGCCACCACAACGTGGGGGGCTTGCCGGAGGAGATGGATTTAAAGGTCTTAGAACCCCTTAGAGATCTCTTCA
AGGACGAGGTCAGAAGAATAGGGGCCATGCTGGATGTGCCCGAGGTCATTTTGAAACGGCACCCATTCCCAGGGCCTGGA
CTAGCGGTTAGATGTTTGGGTGAGATCACTCCTGAACGCCTTGATACGCTGAGGAAGGCTGACAAAATCTTCTTGGAAGA
AATAAGAAAAGAGGGGCTTTACGACGAGATCTGGCAGGCTTTCTGTGTTCTGCTGCCAGTAAAGACCGTGGGCGTTATGG
GAGACGTAAGAACCTACGCAGAGATAGTGGGTCTGAGGGCAGTGAGTTCTCAGGATGGCATGACCGCTGATTGGGTCAAG
CTCCCCATGGAACTTTTGGACAGGGTCTCTCGGCGCATCTGCAATGAGGTCCCTGGCGCGAACAGGGTGGTCTACGATGT
CACCAGCAAGCCGCCTTCCACGATAGAGTGGGAGTAG

Protein sequence :
MGNSTSAIEEKVIVLDCGSQYTQLIARRIRELGVYSEILPWDTPYEEIAQQSPKGIVISGGPSSVREEDSPTVPEDVLSG
KVPVLGICYGMQLIAHMLGGVVKKGPFAEYGKATVNVTDPNADIFYGVSSPLQVWMSHWDYVEQPPKGFKVAARSESGMI
ASIYNDDLNVWALQFHPEVWHTQQGSKILENFLFKICKCKGLWDLEGWIDMMTKQIKETVGQDKVICGLSGGVDSTVAAV
LTHKAIGDNLECIFVDNGLLRMNEAQEVLKVYEDLHLKVHAVDAREEFLSALKGVTDPERKRKIIGEIFIRVFEKKANEI
GGAKWLLQGTVYPDVIESGKKGKDAAVIKSHHNVGGLPEEMDLKVLEPLRDLFKDEVRRIGAMLDVPEVILKRHPFPGPG
LAVRCLGEITPERLDTLRKADKIFLEEIRKEGLYDEIWQAFCVLLPVKTVGVMGDVRTYAEIVGLRAVSSQDGMTADWVK
LPMELLDRVSRRICNEVPGANRVVYDVTSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-127 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-128 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-128 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-112 48