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Name : Tlie_1599 (Tlie_1599) Accession : YP_004933418.1 Strain : Thermovirga lienii DSM 17291 Genome accession: NC_016148 Putative virulence/resistance : Virulence Product : ATP-dependent chaperone ClpB Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : - Position : 1664729 - 1667341 bp Length : 2613 bp Strand : - Note : PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase associated with various cellular activities (AAA); TIGRFAM: ATP-dependent chaperone ClpB; COGs: COG0542 ATPase with chaperone activity ATP- DNA sequence : ATGGATATGAATAAATTAACTCAGAAATCACAGGAAGCGCTGGCGGATGCCCAAAAAGAAGCAATCCAAAGAGGCCATAG AGAGGTAGATAACGAGCACCTGCTGCTCGCGTTGCTGAAGCAGGAAAACGGTCTTATACCGAGACTGATGAGGAAGATGG ACGTTCCATTGGATGCGATGATAAATGCCGTGGAAAAAGAGTTGGCGAGGCGACCAAGCATTGCAGGAGCGTCCTTGGAG GCCGGTAAAATTTATATTTCCGGCAGGTTGGGGGCTGTTTTGGTCGCAGCTGAAGAAAAAGCCAAGAAATTGAAGGACGA ATATGTTTCGGTGGAGCACCTTTTCAGTGCCCTTATGGAGGAGCCGGATCCCAGCTCACCAACCAGAAAGATATTAGCTG ATTTTGGGGTCGACGAGGATAGATTCTTCAAAACTCTCCAGGAGGTCAGGGGGAACCAGAGGGTTCAAAGCGCCGATCCA GAGAGTACCTATGAAGCACTTGAAAAGTACGGCAGGGACCTTGTGGCTCTTGCGAGGGCAGGGAAACTGGATCCTGTCAT AGGAAGAGACGAGGAAGTAAGGCGAGTCATAAGAATCTTGAGCAGGAGAACCAAGAACAATCCGGTTCTTATAGGTGAAC CTGGCGTAGGTAAGACTGCCATAGTCGAAGGTTTGGCGCAGCGGATCGTAAGAGGTGATGTGCCTGAAGGGCTCAGGGAT AGGAGCATTGTGGCCCTTGACATGGGTGCCCTAGTGGCTGGTGCCAAGTACAGAGGAGAATTCGAGGAGAGACTCAAGGC TGTATTGAACGAGGTTAAAAGGAGCGAAGGTCGCATAATACTATTCATAGATGAGATCCACACTATTGTGGGTGCAGGCA GGGCAGAAGGTTCTATGGACGCGGGCAACATGTTGAAACCCATGCTTGCCAGAGGAGAGCTTCACTGTATAGGTGCTACT ACTCTTGACGAGTACAGGAAATACATAGAAAAGGATGCTGCCCTGGAACGGAGGTTCCAGCCAGTGTACGTAGACCAGCC CTCAGTGGAAGATACCATATCCATCCTCAGGGGGCTTAAGGAACGTTTTGAAGTGCACCATGGCGTGCGGATACAGGATA ACGCTCTTGTGGCGGCAGCGGTCCTATCTCATAGGTACATAACCGATAGGTTCCTGCCCGACAAAGCCATAGACCTTGTG GATGAAGCTTGCGCCATGGTAAGGACCGAGATCGACTCCATGCCTACGGAGCTGGACACTGTAATGAGGAGGATAATGCA GCTTGAGATAGAAGAAGCTGCCTTGAAAAAGGAGACGGATAAGGCAAGTCAGCAGAGACTTGAAAACCTGAGGAAGGAAC TTCAGGAAGCAAGAGAGAAAGCAGATGCCCTGAGGGCCCAGTACGAAGTGGAGAAAAAACTGATCTCTGAGGTCCAGAGT TTGCGAGAAGAGATAGAAAAGGTAAAACATGAGATAGAGAAAGCAGAAAGAGAATATGACCTCAACAAGGCAGCCGAGCT CAAGCACGGTAAGCTTCCTGAACTTGAGATGAAACTGCAGGAGGCGCAAAAACGCCTGGAGGACTCGGGACAGAGGCTCT TGAGGGAGGAAGTAACCGAGGAAGAGATAGCCAAGGTGGTCTCCATGTGGACTGGTATTCCTGTTAGCCGTCTCATGGAG GGAGAACGAGAAAAGTTGCTTAGACTTGAAGAAGTGTTGCACCAGAGGGTTGTTGGTCAGGATGAAGCGGTAAAACTTGT GGCTGACGCGGTGCTCAGAGCCAGGTCTGGAATAAAGGATCCCAGAAGGCCTATAGGTTCCTTCATATTCTTGGGTCCTA CTGGGGTTGGTAAGACGGAACTTGCCAAGACATTGGCGGAGGCCTTGTTCGACAGTGAGGATAACTTGATAAGGATAGAT ATGTCCGAATACATGGAGAAACATGCAGTCTCCCGATTGATAGGAGCTCCGCCTGGCTACGTGGGGTATGAAGAAGGTGG CCAGCTGACGGAAAGGGTCAGAAGGAAGCCCTACTCGGTCATCTTATTCGACGAGATAGAAAAGGCGCATCAGGATGTGT TCAACATCCTTCTTCAGGTACTGGACGATGGACGCCTCACTGACAGCCACGGAAGGACTGTGGATTTTAGAAACACCATA ATAATCATGACCAGCAACATCGGAGCAACTGCCCTGATGGAGGGTATTACAGAAAGTGGAGAGATCACCGAGGAAGCTCG AAATGAAGTGACAAGGCAGCTAAGACTTCACTTCAGGCCAGAGTTCCTCAACAGGGTGGACGATGTGGTGCTGTTCAAGC CATTGAGACAAGAGGAATTGGTGAAGATAGTGGATCTGTTGACTGCAGATTTGAAGGAGAGGTTACAGGAGCGCTCCGTC ACCCTTGAACTGACACAAGAAGCCAAAACCTTCATAGCGAGGGAAGGCAGCGATCCGGTGTATGGTGCGAGGCCTTTGAA GCGCTTCATTGCTCACGAGCTTGAGACCAAGATAGCGAGGATGATCCTTAAAGGAGAACTTTGCGAAGGCTCCAAGCTTA CCGTTGATTCGGATGGAGAAAAACTGACCTTCTCCGTTTCCGTGTCTGCATAA Protein sequence : MDMNKLTQKSQEALADAQKEAIQRGHREVDNEHLLLALLKQENGLIPRLMRKMDVPLDAMINAVEKELARRPSIAGASLE AGKIYISGRLGAVLVAAEEKAKKLKDEYVSVEHLFSALMEEPDPSSPTRKILADFGVDEDRFFKTLQEVRGNQRVQSADP ESTYEALEKYGRDLVALARAGKLDPVIGRDEEVRRVIRILSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVRGDVPEGLRD RSIVALDMGALVAGAKYRGEFEERLKAVLNEVKRSEGRIILFIDEIHTIVGAGRAEGSMDAGNMLKPMLARGELHCIGAT TLDEYRKYIEKDAALERRFQPVYVDQPSVEDTISILRGLKERFEVHHGVRIQDNALVAAAVLSHRYITDRFLPDKAIDLV DEACAMVRTEIDSMPTELDTVMRRIMQLEIEEAALKKETDKASQQRLENLRKELQEAREKADALRAQYEVEKKLISEVQS LREEIEKVKHEIEKAEREYDLNKAAELKHGKLPELEMKLQEAQKRLEDSGQRLLREEVTEEEIAKVVSMWTGIPVSRLME GEREKLLRLEEVLHQRVVGQDEAVKLVADAVLRARSGIKDPRRPIGSFIFLGPTGVGKTELAKTLAEALFDSEDNLIRID MSEYMEKHAVSRLIGAPPGYVGYEEGGQLTERVRRKPYSVILFDEIEKAHQDVFNILLQVLDDGRLTDSHGRTVDFRNTI IIMTSNIGATALMEGITESGEITEEARNEVTRQLRLHFRPEFLNRVDDVVLFKPLRQEELVKIVDLLTADLKERLQERSV TLELTQEAKTFIAREGSDPVYGARPLKRFIAHELETKIARMILKGELCEGSKLTVDSDGEKLTFSVSVSA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| clpC | YP_005163377.1 | ATP-dependent Clp protease ATP-binding subunit | Not tested | Not named | Protein | 2e-152 | 43 |
| STY0294 | NP_454876.1 | ClpB-like protein | Not tested | SPI-6 | Protein | 8e-99 | 42 |
| aec27 | AAQ96721.1 | Aec27 | Not tested | AGI-1 | Protein | 9e-98 | 41 |
| aec27 | YP_851418.1 | ATPase | Not tested | PAI II APEC-O1 | Protein | 1e-97 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| Tlie_1599 | YP_004933418.1 | ATP-dependent chaperone ClpB | VFG2076 | Protein | 2e-115 | 43 |
| Tlie_1599 | YP_004933418.1 | ATP-dependent chaperone ClpB | VFG2084 | Protein | 3e-105 | 43 |
