Gene Information

Name : DSC_04250 (DSC_04250)
Accession : YP_004929544.1
Strain : Pseudoxanthomonas spadix BD-a59
Genome accession: NC_016147
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 710373 - 712388 bp
Length : 2016 bp
Strand : -
Note : COG0550 Topoisomerase IA

DNA sequence :
ATGCGCGTGGTTCTGTGCGAGAAGCCTTCCCAGGGCAAGGACATCGCCCGCGTCCTGGGCGCCACGCAGCGAGGCAACGG
CTGCTACACCGGCTCTGGCCTCGGCGTGACCTGGGGCATCGGCCATCTGATCGAGACCGCTCCCCCGGAAGCCTACGGTG
AGCAGTACAAGCGATGGGCGCTGGAACCGCTGCCCATCATTCCCCAGCACTGGCAGGTCGTGGTCAAGGCCAAGACCGCC
ACGCAGTTCAAGGTCGTCAAGCAGCTGCTGGCACAGGCCACCGATCTGGTGATCGCGACCGACGCCGATCGCGAGGGCGA
GATGATCGCCCGCGAGCTGATCGACTACTGCGGCTACCGCGGCCCGATCCAACGGCTGTGGTTGTCCGCGCTCAACGATG
CGTCGATCCGCAAGGCACTCGGCGCGCTCAAGCCGTCCGGCGAGACGTTGCCGCTGTACTACTCGGCCCTGGCGCGCTCG
CGCGCCGACTGGCTGATCGGCATGAACCTGAGCCGGCTATTCACTGTGCTCGGGCGCCAGGCCGGCTATTCCGGCGTGCT
GTCGGTCGGTCGCGTGCAGACGCCGACGCTGAAGCTCGTCGTGGACCGCGACCGCGAGATCGCGCGCTTCGTCTCCGTGC
CGTTCTGGACGATCGAGGTGTTGCTGGCTCATGCCGGCCAGTCCTTCGTGGCCAACTGGACGCCTCCGGCGGGTTGCACC
GACGACGCCGGGCGCTGCCTGCAGCAGCCCGTCGCGCAGCAGGCGGACGAACGCATGCGCGCGGCCGTCAGCGCGCAAGT
GGTGTCCGTCGAGACCGAGCGCATGCGCGAGGGACCGCCGCTGCCGTTCGACCTGGGAACGCTTCAGGAAGTGTGTTCCA
AGCAGCTTGGGCTGGACGTGCAGGAGACGCTGGACATCGCGCAGTCCCTCTACGAGACGCACAAGGCCACGACCTATCCT
CGCTCGGATTCGGGCTATCTGCCCGAGAACATGCTGGCCGAAGTGCCGACCGTACTCGACAGCCTGGTCAAGACCGATCC
AAGCCTTCGCCCGCTGGTCGCCAAGCTCGATCCCCATCAGCGCTCGCGCGCATGGAACGACGCCAAGGTCACGGCGCACC
ACGGCATCATTCCAACGCTCGAACCGGCGAACCTATCGGCCCTGAACGACAAGGAGCTGGCCGTCTACCGACTGATCCGC
GCCCACTACCTCGCACAGTTCCTGCCGCATCACGAGTTCGACCGCACCGTGGCGCAGTTCGCGTGCGCCGGCCAGTCGCT
CACCGTGGTCGGCAAGCAGATTGTCGTGACCGGCTGGCGCCAGGTGCTGGCGGCGCCGGCACCGGACGAACCGGACGAGG
ACGCACAGCGCAGCCAGGTGCTGCCCGCGCTGCACGCCGGCTTGTCATGCCCCATCGGCGCCGTCGATCTGAAGGCATTG
AAGACCCTGCCGCCCAAGCCGTACACGCAGGGCGAGCTGGTCAAGGCCATGAAGGGCGTCGCCAGGCTGGTCACCGACCC
GCGGCTCAAGCAGAAGCTCAAGGACACCACCGGCATCGGCACCGAGGCCACGCGCGCCAACATCATCAACGGACTGCTGG
GCCGCGGCTATCTGCTGAAGAAGGGCCGCGCGATCCGGGCTTCCGATGCGGCCTTCACCCTGATCGACGCGGTGCCGCCA
GCGATCGCAGATCCGGGCACGACCGCCGTGTGGGAACAGGCGCTGGACATGATCGAAGCGCGGCAGATGACGCTGGACGC
CTTCATCGCCAAGCAATCCGCCTGGGTCGCCCAGCTCGTGCAGCAATACCGCACCGCAACGCTCTCCATCCAACTGCCAC
CCGCGCCAGCCTGTCCGCAATGCGGCTCGCCGATGCGCCAGCGCACGGGCAAGAGCGGTGCCTTCTGGTCCTGTAGCCGC
TATCCGGACTGCAAGGGCACGATGGCCATCGAATCCGCGACCGGCGGCAAGCGCAGCGCGCCGCGCAAGCGGCGCACCGC
ACCCAAGGCGTCCTGA

Protein sequence :
MRVVLCEKPSQGKDIARVLGATQRGNGCYTGSGLGVTWGIGHLIETAPPEAYGEQYKRWALEPLPIIPQHWQVVVKAKTA
TQFKVVKQLLAQATDLVIATDADREGEMIARELIDYCGYRGPIQRLWLSALNDASIRKALGALKPSGETLPLYYSALARS
RADWLIGMNLSRLFTVLGRQAGYSGVLSVGRVQTPTLKLVVDRDREIARFVSVPFWTIEVLLAHAGQSFVANWTPPAGCT
DDAGRCLQQPVAQQADERMRAAVSAQVVSVETERMREGPPLPFDLGTLQEVCSKQLGLDVQETLDIAQSLYETHKATTYP
RSDSGYLPENMLAEVPTVLDSLVKTDPSLRPLVAKLDPHQRSRAWNDAKVTAHHGIIPTLEPANLSALNDKELAVYRLIR
AHYLAQFLPHHEFDRTVAQFACAGQSLTVVGKQIVVTGWRQVLAAPAPDEPDEDAQRSQVLPALHAGLSCPIGAVDLKAL
KTLPPKPYTQGELVKAMKGVARLVTDPRLKQKLKDTTGIGTEATRANIINGLLGRGYLLKKGRAIRASDAAFTLIDAVPP
AIADPGTTAVWEQALDMIEARQMTLDAFIAKQSAWVAQLVQQYRTATLSIQLPPAPACPQCGSPMRQRTGKSGAFWSCSR
YPDCKGTMAIESATGGKRSAPRKRRTAPKAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 0.0 77
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 0.0 77
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 0.0 65
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 1e-169 52
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 1e-169 52
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 9e-170 52
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 2e-161 51
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 7e-167 49
topB AAW83109.1 TopB Not tested GGI Protein 3e-118 41