Gene Information

Name : DSC_03965 (DSC_03965)
Accession : YP_004929487.1
Strain : Pseudoxanthomonas spadix BD-a59
Genome accession: NC_016147
Putative virulence/resistance : Resistance
Product : arsenical pump membrane protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1055
EC number : -
Position : 660456 - 661760 bp
Length : 1305 bp
Strand : -
Note : COG1055 Na+/H+ antiporter NhaD and related arsenite permeases

DNA sequence :
ATGCTTGCCCTTGCGATTTTCATCGTCACTCTTGTATTCGTCATTTGGCAGCCGCGAGGGTTCGGTATCGGTTGGTCGGC
ACTGGCCGGCGCCGCAGTAGCGTTGGCCACCGGCGTCGTCGGGTGGGGTGACGTCGCCACGGTGTGGGGGATTGTCTGGG
ATGCGACGTTTACTTTCGTCGCACTCATCATCATCTCGCTCATCCTAGACGCGGCCGGCTTCTTCGCATGGGCGGCGCTG
CACGTGGCGCGCTGGGGCGGCGGCAGTGGTCGGAAACTCTTTCCGCTGATCGTCTTGCTTGGCGCTGCGATCGCGGCAGT
GTTCGCCAACGATGGCGCGGCTCTCCTGTTGACGCCGATTGTTCTTGCCATTCTGTTGCGCTTGAACTTTCCACCCGCGA
GTGCGCTCGCGTTTACTGTGGCCTGCGGTTTCATCGCTGATACGGCCAGCCTGCCGCTGGTTGTCTCGAACTTGGTCAAC
ATCGTCACCGCGAACTTTTTTGACGTCTCGTTCGGGCGCTACGCAGCGGTCATGGTGCCGGTGAATCTGGTGTCGGTCGG
CGCCACGCTGATCGTCCTGTGGCTCTGGTTCCGCCGCGACATTCCCCGCACCTACCCGGTCCACGATCTTGAAGCGCCGC
ATGAGGCGATCCGCGACAAGGCGGTCTTCCGCGCCGCCTTGCCCCTGCTCGCATCACTGCTCCTTGCCTACTTCGTGACC
GGGCCGCTGGGCGTCCCGATCGCCTTGGTGACGGGTGTGGCTGCGCTGGTGCTGATGGCAATTGCAGGTCGCTGGGCGAC
AGGCGGCCGAGGCGCCACCATGGCCGTGACCAAGATTCTGCGTGGCGCGCCCTGGCAGATCGTGCTGTTCTCGGTTGGCA
TGTATCTGGTGGTTTATGGGCTTGGCAACGCCTGGCTGACAAAGGCTGCAAGTGCGGTGCTTGAGTGGCTGGCGGCGCAG
GGAACCTTTGTGGCCACGATCGGCACCGGCTTCGCAGTGGCGGGCCTCGCTTCGATCATGAACAACATGCCGGCGACGCT
GGTGGGCGCACTGGCCATCGACGGGGCCAATCTTCCGGCCGCCACCCGCGAATTGATGATCTATGCCAACGTCGTGGGCA
ACGACCTTGGCCCCAAGCTCACTCCGATTGGGTCGCTCGCGACCCTGCTGTGGCTGCACGTCCTCGCCGGCAAGGGCCAA
CGGATCACGTGGGGACAGTACATGAAGGTAGGGCTAATCCTCACGCCCCCGGTCCTGTTGGCCACGCTCGTCGCCCTCTG
GATTTGGCTGCCGCTCGCTCAATGA

Protein sequence :
MLALAIFIVTLVFVIWQPRGFGIGWSALAGAAVALATGVVGWGDVATVWGIVWDATFTFVALIIISLILDAAGFFAWAAL
HVARWGGGSGRKLFPLIVLLGAAIAAVFANDGAALLLTPIVLAILLRLNFPPASALAFTVACGFIADTASLPLVVSNLVN
IVTANFFDVSFGRYAAVMVPVNLVSVGATLIVLWLWFRRDIPRTYPVHDLEAPHEAIRDKAVFRAALPLLASLLLAYFVT
GPLGVPIALVTGVAALVLMAIAGRWATGGRGATMAVTKILRGAPWQIVLFSVGMYLVVYGLGNAWLTKAASAVLEWLAAQ
GTFVATIGTGFAVAGLASIMNNMPATLVGALAIDGANLPAATRELMIYANVVGNDLGPKLTPIGSLATLLWLHVLAGKGQ
RITWGQYMKVGLILTPPVLLATLVALWIWLPLAQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 9e-87 59
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 5e-74 51
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 3e-78 51
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 1e-72 50

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
DSC_03965 YP_004929487.1 arsenical pump membrane protein BAC0578 Protein 3e-87 60
DSC_03965 YP_004929487.1 arsenical pump membrane protein BAC0576 Protein 8e-87 60
DSC_03965 YP_004929487.1 arsenical pump membrane protein BAC0577 Protein 2e-86 59
DSC_03965 YP_004929487.1 arsenical pump membrane protein BAC0031 Protein 1e-84 59
DSC_03965 YP_004929487.1 arsenical pump membrane protein BAC0575 Protein 1e-76 50
DSC_03965 YP_004929487.1 arsenical pump membrane protein BAC0574 Protein 1e-72 50