Gene Information

Name : Sfla_0494 (Sfla_0494)
Accession : YP_004921476.1
Strain : Streptomyces flavogriseus ATCC 33331
Genome accession: NC_016114
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 574655 - 576172 bp
Length : 1518 bp
Strand : +
Note : PFAM: Aldehyde Dehydrogenase; KEGG: nfa:nfa29950 aldehyde dehydrogenase

DNA sequence : 
ATGGTGTACGCGCAGCCAGGAACGGAAGGCAGCATCGTCGCCTTCGCCCCGCGATACGACAACTTCATCGGCGGCGAGTG
GGTCGCCCCGGTCGAAGGCCGGTACTTCGACAACCCGTCACCGGTGAACGGCAAGGTCTTCTGCGAGGTCGCCCGCTCCT
CGGCGGCAGACGTGGAACTCGCCCTGGACGCGGCGCACGCCGCAGCCGATCGGTGGGGCCGCACCTCGGCGACGGAACGC
GCCAACATCCTCAACAGGATCGCGAACCGGCTCGAGGAGCACCTCGAGAAGATCGCGGTGGCCGAGACCTGGGAGAACGG
CAAGCCGGTCCGGGAGACGCTGGCCGCCGACATCCCCCTCGCGATCGACCACTTCCGGTACTTCGCCGGGGTGGTGCGGG
CGCAGGAGGGCAGCATCGCCGAGATCGACGCGGACACGGTCGCGTACCACTTCCACGAGCCGCTGGGTGTGGTCGGTCAG
ATCATCCCGTGGAACTTCCCGATCCTGATGGCCACATGGAAGCTCGCCCCCGCCCTCGCCGCCGGCAACTGCGTGGTCAT
CAAGCCGGCGGAGCAGACGCCTGCCAGCCTGCTGCTGGTCGTCGAGCTGATCGCGGACCTGCTGCCTCCGGGCGTGGTCA
ACGTCGTCAACGGATTCGGCATCGAGGCGGGCAAACCCCTCGCGTCCAGCTCCCGGGTCGCGAAGGTGGCCTTCACCGGG
GAGACCACGACCGGCCGCCTGATCATGCAGTACGCGAGCGAGAACATCATCCCCGTCACGCTGGAACTGGGCGGCAAGAG
CCCGAACATCTTCCTGCCCGACGTGATGGCCGCCGACGACGACTTCCTGGACAAGGCCGTCGAGGGCCTCGTGATGTTCG
CCCTCAACTCGGGCGAGGTGTGCACCTCCCCCTCCCGGGCCCTGGTCCACTCCTCGATCTACGACGAGTTCATGGCCCGC
TGCGTCGAACGGACCCGGGCCATCGTCAGCGGCGACCCGCTGGACCCGGCGACCATGATCGGCGCACAGGCGAGCAACGA
GCAGTACGAGAAGATCCTCTCCTACGTGGACATCGGCAGGAAGGAGGGCGCCGAGATCCTCACCGGCGGCACGCCCCGGA
CCGTGGCCGGCCTGGAGGACGGCTTCTACATCGAGCCGACCGTCTTCCGCGGCACCAACGACATGCGGATCTTCCAGGAG
GAGATCTTCGGACCGGTCCTCTCCGTCACCACGTACGACTCGGTCTCCGAGGCCCTGAAGATCGCCAACGACACCCTGTA
CGGGCTCGGCGCGGGCGTGTGGTCCCGGGACGGCAACACCGCCTACCGGCTCGGCCGCGAGATCAAGGCGGGCCGTGTGT
GGACCAACTGCTACCACGCCTACCCCGCCCATGCGGCGTTCGGCGGTTACAAGAACTCCGGCATCGGCCGCGAGAACCAC
AAGATGATGCTGGACCACTACCAGCAGACGAAGAACCTATTGGTGTCGTACTCGCCGAAGAAGCTGGGGTTCTTCTAG

Protein sequence : 
MVYAQPGTEGSIVAFAPRYDNFIGGEWVAPVEGRYFDNPSPVNGKVFCEVARSSAADVELALDAAHAAADRWGRTSATER
ANILNRIANRLEEHLEKIAVAETWENGKPVRETLAADIPLAIDHFRYFAGVVRAQEGSIAEIDADTVAYHFHEPLGVVGQ
IIPWNFPILMATWKLAPALAAGNCVVIKPAEQTPASLLLVVELIADLLPPGVVNVVNGFGIEAGKPLASSSRVAKVAFTG
ETTTGRLIMQYASENIIPVTLELGGKSPNIFLPDVMAADDDFLDKAVEGLVMFALNSGEVCTSPSRALVHSSIYDEFMAR
CVERTRAIVSGDPLDPATMIGAQASNEQYEKILSYVDIGRKEGAEILTGGTPRTVAGLEDGFYIEPTVFRGTNDMRIFQE
EIFGPVLSVTTYDSVSEALKIANDTLYGLGAGVWSRDGNTAYRLGREIKAGRVWTNCYHAYPAHAAFGGYKNSGIGRENH
KMMLDHYQQTKNLLVSYSPKKLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aldA ACK75590.1 aldehyde dehydrogenase Not tested VPI Protein 6e-93 62
aldA ACK75596.1 aldehyde dehydrogenase Not tested VPI Protein 6e-93 62
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-135 62
aldA ACK75577.1 aldehyde dehydrogenase Not tested VPI Protein 4e-93 62
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 3e-144 62
aldA ACK75585.1 aldehyde dehydrogenase Not tested VPI Protein 2e-92 62
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 3e-144 62
aldA ACK75593.1 aldehyde dehydrogenase Not tested VPI Protein 2e-92 62
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 3e-144 62
aldA ACK75574.1 aldehyde dehydrogenase Not tested VPI Protein 6e-93 62
aldA ACK75582.1 aldehyde dehydrogenase Not tested VPI Protein 5e-93 62
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-143 62
aldA ACK75588.1 aldehyde dehydrogenase Not tested VPI Protein 3e-93 61
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 4e-65 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sfla_0494 YP_004921476.1 aldehyde dehydrogenase VFG0082 Protein 5e-136 62