Gene Information

Name : Sfla_4818 (Sfla_4818)
Accession : YP_004925736.1
Strain : Streptomyces flavogriseus ATCC 33331
Genome accession: NC_016114
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 5555630 - 5557063 bp
Length : 1434 bp
Strand : +
Note : TIGRFAM: pyruvate kinase; KEGG: sgr:SGR_5516 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta

DNA sequence :
ATGCGCCGAGCAAAAATCGTTTGTACCCTGGGACCCGCCACCGACTCGTACGAGCAGATCAAGGCACTCGTCGAAGCGGG
AATGGACATCGCCCGCCTCAACCTCAGCCACGGCACCTACGCCGAACACGAAGAGCGCTACCACCACGTGCGCAAAGCCT
CCGAGGAAACCGGCCGCAGCGTAGGAATCCTCGCCGACCTTCAAGGCCCGAAGATCCGCCTCGGCCGCTTCGCCGAAGGC
CCCGTACTCCTTGAACGCGGCGACGACTTCACCATCACCGTCGAACCCATGGAAGGCGACCGCCACACCTGCGGCACCAC
CTACGACGGACTCGCCGCCGACGTCACCACCGGCGAACGCATCCTCATCGACGACGGCCGCGTCACCCTCGAAGTCACCG
ACATCGACGGACCCCGCGTCCACACCACCGTCATCGAAGGCGGCATGGTCTCCGACCACAAGGGACTCAACCTCCCCGGC
GTCGCCGTCTCGGTCCCCGCGCTCTCCGAGAAGGACATCGAAGACCTCCGCTGGGCCGTGCGCACCGGCGCCGACGTCAT
CGCCCTCTCCTTCGTGCGCACCGGACGCGACATCGACGACGTCCACCGCGTCATGGACGAGGAGGAGCGCCGCCTCCCCG
TCATCGCCAAGGTCGAGAAGCCCCAGGCCGTCGACCACATCGACGACATCGTCGCCGCCTTCGACGGCATCATGGTCGCC
CGCGGCGACCTCGGTGTCGAAATGCCCCTGGAACAGGTCCCGATCGTCCAGAAGCGCGCCATCAAACTCGCCAAGCGCAA
CGCCAAGCCGGTCATCGTCGCCACCCAGATGCTCGACTCGATGATCGACAACTCCCGCCCCACCCGCGCCGAGGCCTCCG
ACGTCGCCAACGCCGTCATCGACGGCACGGACGCCGTGATGCTCTCCGGCGAGACCAGCGTCGGCAAGTACCCCGTCGAG
ACCGTCCGCACCATGGCCCGCATCGTCGAGGCGGCCGAGAAGGACATCCTCGCCAAGGGCCTCCCGCCCCTCACCGACCG
CAACAAGCCCCGCACCCAGGGCGGCGCGGTCGCCCGCGCGGCAGCCGAGATGGGCGACTTCCTCGGCGCGAAGGCCCTGG
TGGCCTTCACCCAGAGCGGCGACACGGTCAAGCGCCTCTCCCGTTACCGCTCCCCGATCCCGCTGCTGGCCTTCACCCCG
GACCAGGCCACCCGTGCGCAGCTGAACCTGACGTGGGGCGTCGAGACGTTCCTCGGGCCGCACGTGGACTCGACGGACGC
GATGGTGGCGCAGGTGGACGAGGAACTGCTGCGGATCGGCCGCTGTCAGAAGGGCGACATCGTGGTCATCACGGCCGGTT
CCCCGCCCGGGGTCGCCGGCTCCACGAACCTGGTACGGGTGCACCACATCGGCGAGGACGACAGCCCGAAGTAA

Protein sequence :
MRRAKIVCTLGPATDSYEQIKALVEAGMDIARLNLSHGTYAEHEERYHHVRKASEETGRSVGILADLQGPKIRLGRFAEG
PVLLERGDDFTITVEPMEGDRHTCGTTYDGLAADVTTGERILIDDGRVTLEVTDIDGPRVHTTVIEGGMVSDHKGLNLPG
VAVSVPALSEKDIEDLRWAVRTGADVIALSFVRTGRDIDDVHRVMDEEERRLPVIAKVEKPQAVDHIDDIVAAFDGIMVA
RGDLGVEMPLEQVPIVQKRAIKLAKRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGKYPVE
TVRTMARIVEAAEKDILAKGLPPLTDRNKPRTQGGAVARAAAEMGDFLGAKALVAFTQSGDTVKRLSRYRSPIPLLAFTP
DQATRAQLNLTWGVETFLGPHVDSTDAMVAQVDEELLRIGRCQKGDIVVITAGSPPGVAGSTNLVRVHHIGEDDSPK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-82 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-82 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-82 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-82 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Sfla_4818 YP_004925736.1 pyruvate kinase VFG0479 Protein 8e-83 42